Acquired Immunodeficiency Syndrome ( Aids ), Caused By Human Immunodeficiency Virus

704 Words Apr 19th, 2015 3 Pages
Acquired immunodeficiency syndrome (AIDS), caused by human immunodeficiency virus (HIV) infection, is still one of the most important challenges, and it has been known that over 370,000 infants pick up HIV infections globally each year [1-3]. More than 10% of all new HIV infections by vertical transmission of HIV from an HIV-positive mother to her baby that can occur at three stages: during pregnancy, during childbirth, and through breastfeeding [5-7]. HIV-infected infants and young children have augmented risk of death due to rapid progression of disease [5]. 30% of untreated HIV-infected children die before 12 months and more than 50% die before 2 years of age [6], suggesting the urgent need for identifying and providing of life-saving medicine. The risk of transmission can be notice remarkably reduced from 20 to 45% to less than 2% with that include a life-saving package of services consisting of ARV prophylaxis and treatment, delivery by Caesarean section, and counseling on breastfeeding [7]. Moreover, only 28% of children born to HIV-positive mothers received a HIV test within the first two months of life [8]. Moreover, the challenge in resource-limited settings is identifying HIV-infected infants and providing early access to this life-saving medicine [8].
Current point-of-care (POC) rapid diagnostic tests (RDT) for HIV are immuneaffinity tests [9-13]. However, they cannot apply for infants and young children, because they are difficult to interpret in infants and…

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