A Brief Note On The Immune Deficiency Foundation Essay
Phagocytes are white blood cells that can surround and ingest microorganisms into tiny compartments in the cell. These compartments, called phagosomes, are filled with chemicals that help kill bacteria and fungi. These compounds include hydrogen peroxide and bleach, which are made in these compartments. (IDF, 2013)
NORD described the defect as a result of mutations in any one of five different genes caused by a mistake in an enzyme called phagocyte NADPH oxidase (2015). NORD stated that particular white blood cells use this enzyme, phagocyte NADPH oxidase, to produce hydrogen peroxide, which cells need to kill certain bacteria and fungi (2015). The lack of the enzyme causes the patient to have a deficit in their immune system, lacking defenses against certain bacteria and fungi.
Boys affected with the disease go through many life-threatening infections. The sources classified the bacteria and fungi that affected patients as Staphylococcus aureus, Burkholderia cepacia complex, Serratia marcescens, Nocardia, and Aspergillus. The Immune Deficiency Foundation stated that the infections can involve any organ or tissue, but the most commonly affected areas are the skin, lungs, lymph nodes, liver and bones (2013). Many sources included these sites as familiar places of infection, but the Immune Deficiency Foundation also described the location of infection of lymph nodes as being under the arm, in the groin, or in the neck (2013).…