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125 Cards in this Set

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1. skeletal


2. cardiac


3. smooth

3 types of muscle tissue

muscle fibers

elongated skeletal and smooth muscle cells are also known as...

skeletal muscle tissue

muscle tissue attached to and covering the bony skeleton, responsible for body motility; 40% of body mass

- voluntary


- striated


- multinucleate

Describe skeletal muscle (movement, appearance, nucleus):

cardiac muscle tissue

muscle tissue forming the walls of the heart, help pump blood through the cardiovascular system

- involuntary


- striated


- uninucleate or binucleate

Describe cardiac muscle (movement, appearance, nucleus):

smooth muscle tissue

muscle tissue found in the walls of hollow organs, propels substances and maintains blood pressure

- involuntary


- nonstriated, spindle-shaped


- uninucleate

Describe smooth muscle (movement, appearance, nucleus):

1. excitability


2. contractility


3. extensibility


4. elasticity

4 special characteristics of muscle tissue

excitability (responsiveness)

the ability to receive and respond to a stimulus

contractility

the ability to shorten forcibly when stimulated

extensibility

the ability to extend or stretch

elasticity

the ability of a muscle cell to recoil and resume its resting length after stretching

1. movement


2. posture


3. joint stability


4. body heat


5. protection

5 most important functions of muscle

fascia

connective tissue that binds separate muscles into functional groups

1. muscle


2. fascicle


3. muscle fiber


4. myofibril


5. myofilament

5 levels (of rods) forming a muscle

1. epimysium


2. perimysium


3. endomysium

3 connective tissue sheaths surrounding muscle fibers (superficial to deep)

epimysium

the layer of dense irregular connective tissue surrounding the whole muscle

fascicle

a group of muscle fibers within each skeletal muscle; resembles a bundle of sticks

perimysium

the layer of fibrous connective tissue surrounding each fascicle

endomysium

the layer of areolar connective tissue surrounding each muscle fiber

origin

where muscle is attached to an immovable or less movable bone

insertion

where muscle is attached to a movable bone

direct attachment (fleshy attachment)

muscle attachment in which the muscle itself is fused to bone or cartilage

indirect attachment

common muscle attachment in which muscle connective tissue extends as a tendon or aponeurosis that anchors it to the skeleton

tendon

flexible but inelastic tissue attaching a muscle to a bone

aponeurosis

a sheet of fibrous tissue that takes the place of a tendon in sheetlike muscles with a wide area of attachment

sarcolemma

a muscle fiber's plasma membrane

sarcoplasm

a muscle fiber's cytoplasm

1. glycosomes


2. myofibril

2 special inclusions in muscle fiber sarcoplasm

glycosomes

granules of stored glycogen that provide glucose during muscle cell activity

myoglobin

a red pigment that stores oxygen in the sarcoplasm

myofibrils

hundreds to thousands of parallel-running rods that make up a single muscle fiber; 80% of cell volume

A band

the dark area of a myofibril

H zone

the light area in the middle of an A band on a myofibril

M line

the dark line running through each H zone on a myofibril, holds thick filaments together

I band

the light area of a myofibril

Z disc

the dark, "zig-zag" line intersecting each I band on a myofibril

sarcomere

the region of a myofibril between two Z discs; the functional unit of skeletal muscle

myofilaments

filaments that create the banding pattern of myofibrils

thick filaments

myosin-containing filaments (red) that extend the entire length of the A band, connect at the M line

thin filaments

actin-containing filaments (blue) that extend across the I band and part of the A band

myosin

protein with two globular heads that form cross bridges during muscle contraction

cross bridges

the point where thick and thin filaments link together during muscle contraction

actin

protein forming intertwined strands that serve as an attachment site for myosin's globular heads

1. tropomyosin


2. troponin

2 regulatory proteins found on thin filaments

tropomyosin

polypeptide strands spiraling around actin filaments to help stiffen and stabilize them

troponin

globular complex located on thin filaments that binds to actin, tropomyosin, and calcium ions

elastic filament

filament holding the thick filaments in place, prevents excessive stretching; composed of the protein titin

1. sarcoplasmic reticulum


2. T tubules

2 types of intracellular tubules that help regulate muscle contraction

sarcoplasmic reticulum

interconnecting tubules surrounding each myofibril; regulate intracellular calcium levels

terminal cisternae

large, perpendicular cross channels of sarcoplasmic reticulum at each A band-I band junction

T tubules

tubules from the sarcolemma that protrude deep in to the muscle fiber, increasing surface area; relay nerve impulses to all cells

triad

each terminal cistern-T tubule-terminal cistern pairing

contraction

the activation of myosin's cross bridges; muscle "shortening"

sliding filament model

states that during contraction the thin filaments slide past the thick ones so that their myosin and actin overlap to a greater degree

action potential

an electrical current generated by the sarcolemma

neuromuscular junction (end plate)

junction between a single muscle fiber and an axon's branches, connecting the brain and muscle

synaptic cleft

space separating an axon terminal and a muscle fiber; filled with glycoproteins and collagen fibers

synaptic vesicles

small membranous sacs in the axon terminal that deliver ACh (acetylcholine) to the synaptic cleft

acetylcholine (ACh)

neurotransmitter delivered by axons to muscle fibers; opens Na+ channels on the sarcolemma

junctional folds (motor end plate)

trough-like folds full of ACh receptors, increase surface area on the sarcolemma

acetylcholinesterase

the enzyme that breaks down ACh to its building blocks after it binds to ACh receptors; ends muscle contraction

myasthenia gravis

disease involving a shortage of ACh receptors, resulting in muscle weakness (such as droopy eyelids, difficulty swallowing)

excitation-contraction coupling

the sequence of events leading to muscle contraction, starting with the propagation of an action potential along the sarcolemma until the myofilaments slide

rigor mortis

muscle stiffening after death, due to lack of ATP (that ordinarily end contractions)

muscle tension

the force exerted by a contracting muscle on an object

load

the opposing force exerted on the muscle by the weight of an object

motor unit

one motor neuron and all the muscle fibers it innervates

myogram

a recording of contractile activity

muscle twitch

a motor unit's response to a single action potential of its motor neuron

1. latent period


2. contraction


3. relaxation

3 distinct phases of a twitch myogram

graded muscle responses

the varying degrees of muscle contractions, depend on the demands placed on the muscle

TREPPE

the staircase effect of muscle warm-up; increased calcium and heat makes enzymes more effective

temporal (wave) summation

successive twitches get stronger, and appear to ride on the shoulders of the previous twitch

incomplete (unfused) tetanus

a sustained but quivering muscle contraction

complete (fused) tetanus

a smooth, sustained muscle contraction; appears as a plateau on a myogram

subthreshold stimuli

stimuli that produce no observable contractions

threshold stimulus

the stimulus at which the first observable contraction occurs

maximal stimulus

the strongest stimulus that increases contractile force

1. isotonic


2. isometric

2 main categories of contractions

isotonic contractions

muscle length changes and moves a load, and tension remains relatively constant

1. concentric


2. eccentric

2 types of isotonic contractions

concentric contractions

contractions in which the muscle shortens and does work; ex. picking up a book, kicking a ball

eccentric contractions

contractions in which the muscle generates force as it lengthens; ex. walking up a steep hill

isometric contractions

contractions that occur when a muscle attempts to move a load that is greater than the force the muscle can develop; muscle neither shortens nor lengthens

muscle tone

the slightly contracted state of a relaxed muscle; helps with joint stability and posture

1. direct phosphorylation


2. anaerobic pathway


3. aerobic pathway

3 pathways of regenerating ATP during muscle activity

direct phosphorylation

regenerates ATP using creatine phosphate and ADP; creatine phosphate + ADP ---> creatine + ATP; 15 seconds worth

creatine phosphate

a unique high-energy molecule stored in muscle that helps regenerate ATP (by direct phosphorylation)

anaerobic pathway

relies on glycolysis to create ATP; 30-40 seconds

glycolysis

the breakdown of glucose by enzymes, releasing ATP and pyruvic acid

lactic acid

accumulates under anaerobic conditions; comes from pyruvic acid

aerobic pathway

relies on cellular respiration to create ATP; glucose + oxygen ---> carbon dioxide + water + ATP; hours

aerobic endurance

the length of time a muscle can continue to contract using aerobic pathways

anaerobic threshold

the point at which muscle metabolism converts to anaerobic glycolysis

muscle fatigue

the inability of a muscle to contract, even though it's still receiving stimuli

excess postexercise oxygen consumption (EPOC)

the extra amount of oxygen that the body must take in to restore its reserves after exercise

1. number of muscle fibers


2. size of muscle fibers


3. frequency of stimulation


4. degree of muscle stretch

4 factors affecting the force of muscle contraction (the number of cross bridges that attach)

internal tension

the force generated by cross bridges

external tension

the force transferred from cross bridges to the load

1. muscle fiber type


2. load


3. recruitment

3 factors affecting the velocity and duration of muscle contraction

1. slow


2. fast

2 types of muscle fibers (based on speed)

1. oxidative


2. glycolytic

2 types of muscle fibers (based on method of forming ATP)

oxidative fibers

muscle fibers that rely mostly on oxygen-using aerobic pathways for ATP

glycolytic fibers

muscle fibers that rely mostly on glycolysis for ATP

1. slow oxidative


2. fast oxidative


3. fast glyolytic

3 classes of muscle fibers

endurance exercise

exercises such as swimming, jogging, or biking; stamina, no hypertrophy, aerobic

resistance exercise

exercises such as weightlifting that pit muscles against high-resistance forces; strength, leads to hypertrophy, anaerobic

cross training

use of both aerobic and anaerobic exercises

disuse atrophy

degeneration and loss of muscle mass due to inactivity

1. longitudinal layer


2. circular layer

2 layers of smooth muscle

peristalsis

the propulsive action of smooth muscle, created by alternating contraction and relaxation of its layers

variscosities

bulbous nerve fiber ends that release neurotransmitter in to smooth muscle cells

diffuse junctions

the junctions between smooth muscle cells and variscosities

caveolae

pouchlike infoldings of the smooth muscle sarcolemma that intake extracellular fluid with high Ca2+ concentration; replace T tubules

dense bodies

act as anchoring points for thin filaments in smooth muscle; replace Z discs

calmodulin

the calcium-binding protein in smooth muscle; replaces troponin

1. slow contraction


2. contraction in unison


3. anaerobic glycolysis


4. regulation


5. stretch


6. hyperplasia

6 special characteristics of smooth muscle

1. neural stimulation


2. hormones


3. local chemicals

3 regulators of smooth muscle contraction

1. unitary


2. multi unit

2 main types of smooth muscle

unitary smooth muscle (visceral muscle)

type of smooth muscle forming the walls of all hollow organs except the heart

multi unit smooth muscle

type of smooth muscle in large airways and arteries, arrector pili, and internal eye

myoblasts

embryonic mesoderm cells from which all three types of muscle tissue derive

muscular dystrophy

a group of inherited muscle-destroying diseases that generally appear during childhood