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7 Cards in this Set
- Front
- Back
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What is the significance of IgM ab in the diagnosis of congenital virus infection?
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It means current infection. Exposure has been 1-2 weeks.
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Is the presence of IgG antibody in an infant significant in diagnosis of a congenital infection?
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It means that the infection has been going on longer or it could be maternal ab. You need IgM from neonatal blood to prove that it is a congenital disease
At 2 weeks this is the predominant type of ab. |
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What is the primary route of infection of an infant with rubella? hepatitis B? Herpes type 2, Cytomegalovirus, HIV?
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Rubella- resp. droplets
CMV- type of herpes virus- transmit by infected saliva, breast milk, sexually and through infected blood. Transmission to the fetus is after primary or recurrent infection. HSV 1/2 are transmit perinatally during passage through birth canal. Parvovirus- resp. route. Very infectious. HIV is transmit mainly during birth. It is only rarely passed in breast milk. Hep B is mainly transmit during birth. |
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What are the reasons to be concerned about hepatitis B infection in the newborn? How is it treated?
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Affected kids will become carriers and have congenital disease.
They can get cirrhosis or hepatocellular carcinoma. Treated with HBIG- hep B immunoglobulin. |
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When during pregnancy is an infection with rubella of most concern? Why?
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0-12 weeks 100%
it crosses the placenta in monocytes. After 16 weeks there is normal development with slight risk of abnormalities |
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What is the causative agent of fifth disease?
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Erythema infectiosum caused by Parvovirus
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What test would you order if your patient was exposed to a child with slap cheek disease during her first trimester?
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Slap cheek is parvovirus
Check to see if mom has antibody because it they don’t it may lead to spont. abortion. |
