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84 Cards in this Set

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Nabothian Cyst

benign, simple cyst found in cervical region of uterus

Symptoms of Nabothian Cyst

asymptomatic unless very large

Nabothian Cysts are more common in....

women who have been pregnant

Measurement of Nabothian Cyst

< 2cm

Sonographic Appearance of Nabothian Cyst

-simple
-discrete
-round
-anechoic

-simple


-discrete


-round


-anechoic

What is the most common finding on pelvic ultrasound?

Nabothian Cyst

Adenomyosis

inner lining of uterus (endometrium) breaks through muscle wall of the uterus (myometrium)




AKA endo migrates into myometrium

Adenomyosis is seen in what percent of hysterectomies?

70%




(2/3)

In Adenomyosis, the ectopic glands are typically seen how far below the endo-myometrium junction?




(mmt)

2-3mm

2 Causes of Adenomyosis

1. defect/absence of basement membrane at junction


2. endo migration by lymph of vascular channels

Risk Factor of Adenomyosis

uterine trauma




(more common in mature reproductive age patients)

Signs & Symptoms of Adenomyosis

- uterine tenderness (dull, achy pain)


- dysmenorrhea


- dysfunctional menstrual bleeding (irregular)


- menorrhagia (heavy bleeding for several days)


- uterine enlargement

Differential Diagnosis for Adenomyosis

-fibroids


-pelvic congestion syndrome


-endometriosis


-endometrial polyps


-endometrial carcinoma

Treatment for Adenomyosis




(if patient doesn't want Hysterectomy)

-GnRH inhibitors


-Birth control pills


-nSAIDS (steroids)


-Endometrial Ablation


-Uterine Artery Embolization

The only sure Treatment of Adenomyosis is..

Hysterectomy

Fibroids co-exist with Adenomyosis in what percent of cases?

>60%

Sonographic Appearance of Adenomyosis

-rounded enlargement of uterus WITHOUT focal mass
-abnormal heterogenous myometrium
-poor definition of endomyometrial junction


-Doppler: hypervascularity throughout uterus

-rounded enlargement of uterus WITHOUT focal mass


-abnormal heterogenous myometrium


-poor definition of endomyometrial junction




-Doppler: hypervascularity throughout uterus

*Key Sonographic Finding of Adenomyosis

Enlargement of uterus will be greater posterior to endometrium

Sonographically, how can we differentiate Adenomyosis from Fibroids ?

fibroids- will have focal, defined mass &


peripheral vascularity




adenomyosis- no focal mass & diffuse hypervascularity

Which imaging modality is most sensitive to Adenomyosis? What are the disadvantages?

MRI




-cost


-scheduling


-insurance (pre-cert)

Hystersalpingogram (HSG) & disadvantages

radiology procedure that inserts contrast to look at uterus, fallopian tubes & surrounding area


- not very specific


- very uncomfortable for patients


- does not always provide diagnosis

Appearance of Focal Adenomyosis

-poorly delineated margins


-may appear as intracavitary polyp

Diffuse Adenomyosis




*most common form

- entire uterus involved




- often associated with endometrial hyperplasia & carcinoma

Fibroids

benign growth of uterus

Fibroids AKA...

leiomyomas


myomas


leiomas


fibromyoma

What is the most common tumor of the uterus & female pelvis?

Fibroid

What is a Fibroid composed of?

-smooth muscle


-connective tissue

Incidence of Fibroids

20-30% women over 30


more common in African Americans

Cause of Fibroids

idiopathic




(unknown)

What does Estrogen do to Fibroids?

increases!

Why do Fibroids tend to shrink after menopause?

lack of Estrogen

Do we typically see 1 Fibroid, or multiple?

multiple

What do Fibroids cause in the Uterus?

- enlargement


- surface lobularity (bumpy)

What feature do Fibroids have that allow them to be removed with little disruption to surrounding myometrium?

they are encapsulated

Signs / Symptoms of Fibroids

- palpable pelvic mass


- uterine enlargement


- pelvic pain


- dysfunctional uterine bleeding (DUB)

How do Fibroids in the Endometrium affect pregnancy?

- increased risk of miscarriage

How do Fibroids in the Cervix or Lower Uterine Segment affect pregnancy?

can interfere with delivery


-should be closely monitored

3 Types of Fibroids




& their locations in myometrium

1. Submucosal - innermost
2. Intramural - center
3. Subserosal - outer

1. Submucosal - innermost


2. Intramural - center


3. Subserosal - outer

2 Types of Subserosal Fibroids

1. pedunculated


2. exophytic

Submucosal Fibroid

- innermost
- will affect endometrium

- innermost


- will affect endometrium

Which Fibroid is most likely to cause symptoms? What are they?

Submucosal




- irregular / heavy menses

Intramural Fibroid

- center
- do not effect endo unless large
- usually will not have defined borders 
- usually multiple found = enlargement of uterus

- center


- do not effect endo unless large


- usually will not have defined borders


- usually multiple found = enlargement of uterus



What are Intramural Fibroids sometimes defined as?

"Heterogenous Echotexture"


"Fibroid Uterus"


"Diffuse Enlargement of Uterus"

What is the most common type of Fibroid?

Intramural

Subserosal Fibroids

- outer
- distorts outer contour of uterus (lumpy uterus - ecophytic fibroids)
- can become pedunculated

- outer


- distorts outer contour of uterus (lumpy uterus - ecophytic fibroids)


- can become pedunculated

Pedunculated Fibroid

- grows outside of uterus with a stalk
- can twist and undergo torsion

- grows outside of uterus with a stalk


- can twist and undergo torsion

Parasitic Leiomyoma

exophytic fibroid in close contact with another adjacent pelvic structure and acts as a parasite on the structures blood supply




- can become detached fromuterus completely

What will happen if a parasitic fibroid outgrows their blood supply? And what are the 4 types?

Degenerate


-Hyaline


-Cystic


-Calcific


-Red Degeneration

Hyaline

(Degeneration of fibroid)


-fibrous tissue replaces smooth muscle cells

Cystic

(Degeneration of fibroid)


-hyaline tissue degenerates leads to liquefaction necrosis

Calcific

(Degeneration of fibroid)


-most often occurs after menopause

Red Degeneration

(Degeneration of fibroid)


-acute form; results from muscle infarction


(most common during pregnancy)

What do parasitic leiomyomas look like as degeneration, calcification or growth occur?

-heterogenous


-appear hypoechoic in comparison to myometrium

What are the two differential diagnosis of parasitic leiomyoma?

-adnexal mass (fibroids will have shadowing that varies)


-endometrial polyp (vascularity around periphery in fibroid, one single vessel in polyp)

Sonographic appearance of parasitic leiomyoma

-may appear as focal, hypoechoic mass


-subtile changes in myometrial echotexture


-focal masses: hypoechoic rim

Complications of Parasitic Leiomyoma

-hydronephrosis: large pelvic mass could obstruct ureters


-increased incidence of miscarriages


-can obstruct delivery


-infertility

Treatment of a parasitic leiomyoma

-most commonly no treatment at all


If it's causing symptoms:


-hysterectomy


-myomectomy (taking fibroid out)


-lupron (shrinks fibroids)


-uterine artery embolization (don't want hysterectomy or don't plan to get pregnant)

What is a endometrial polys

-localized overgrowths of endo tissue


-may be peculated, broad-based or thin stalk


-may see 'feeder vessel'

Endometrial Polyps stem from?

ENDOMETRIUM

Leiomyomas stem from?

MYOMETRIUM

Signs and symptoms of Endometrial Polyps

-asymptomatic


-infertility (multiple polyps)


-postmenopausal bleeding (PMB)


-abdominal uterine bleeding (AUB)


-incidental finding on dilation curettage (D&C)

What does Endometrial Polyp look like on ultrasound?

-focal thickening of endo
-discrete mass: focal, round, more hyperechoic
-possible feeder vessel in stalk
-heterogenous as increases in size
-***do not shadow
-sonohysterography (SIS) determine size & location

-focal thickening of endo


-discrete mass: focal, round, more hyperechoic


-possible feeder vessel in stalk


-heterogenous as increases in size


-***do not shadow


-sonohysterography (SIS) determine size & location

Endometrail Hyperplasia

-proliferation of endometrial glandular tissue


-diffuse or may not involve entire endo tissue

What percent of endometrial hyperplasias progress into endo carcinoma?

approx 25%

What are some causes of endometrial hyperplasia?

-unopposed HRT


-persistent and anovulatory cycles


-polycistic ovarian disease (PCOD)


-obesity


-estrogen producing tumors of ovary


(granolas cell tumors, thecomas)

Differential Diagnosis of endometrial hyperplasia?

-u/s should be performed immediately after menses


-D&C with thorough pathology examinations

What does endometrial hyperplasia look like on ultrasound?

-smooth, homogenous, echogenic


-possible cystic changes


Premeno: Echo complex (EC) > 14mm


Postmeno on estrogen only: EC 5mm


Postmeno on cycling in estrogen: 8mm


in porgesterone: EC decreases

Asherman's syndrome

-adhesions of endometrium that develop as a result of trauma

What is asherman's syndrome typically a result of?

-C-section (C/S)


-Dilation Curettage (D&C)


-Elective abortion/Therapeutic abortion


-Miscarriage (at any point)

Asherman's syndrome can result in what?

-infertility or recurrent pregnancy loss

Asherman's Syndrome requires what to diagnose?

-Sonohysterography (SIS)
-HSG still gold standard at this point (x-ray)

-Sonohysterography (SIS)


-HSG still gold standard at this point (x-ray)

What is the treatment for Asherman's Syndrome?

-remove adhesions under hysteroscope

Uterine Sarcoma

(MALIGNANT)


-aggressive with poor prognosis


-early detection increases odds of survival


-difficult to differentiate from degenerating fibroid

Why is it difficult to differentiate a sarcoma from a fibroid?

-local invasion and distant metastasis are clues


-if increases in size from baseline study

What is the most common gynecological malignancy?

Endometrial Carcinoma

What are the risk factors of endometrial carcinoma?

-obesity (50 pds over weight 2 to 3x more likely)


-nulliparous (2 to 3x more likely


-late menopausal (after 52 years)


-pt w hx of polyps


-family hx of EC


-unopposed estrogen (25% develop EC)


-hx of tamoxifen (if there are abnormalities prior, then 18 fold increase of EC)

What causes decreased risks of endometrial carcinoma?

Women on BCP for period of 12 months (safe for 10 years)


-most noticeable in nulliparous pts


Smoking


-decreased obesity


-menopause 1 to 2 years earlier

What are some statistics of endometrial carcinoma

-usually diagnosed in 6-7th decade (50-60 yrs)


-higher in white women


-higher rate of mortality in black women

What are signs and symptoms of endometrial carcinoma

Uterine bleeding


-currently all symptomatic puts should be biopsied

What are the treatments for endometrial carcinoma?

-total hysterectomy


-bilateral salpingo-oophorectomy


-peritoneal fluid aspiration and washing


-possible lymphadenectomy

Whats the sonographic appearance of endometrial carcinoma

-heterogenous echotexture irregular or poorly defined margins
-cystic changes within endo
-may see hydrometra or hematometra
-enlargement of ut w lobular contour
-pelvic fluid or ascites

-heterogenous echotexture irregular or poorly defined margins


-cystic changes within endo


-may see hydrometra or hematometra


-enlargement of ut w lobular contour


-pelvic fluid or ascites

What will the subendometrail halo look like on ultrasound with endometrial carcinoma is present?

If distinct- carcinoma may be localized
Not distinct- nice halo but broken in one spot (greater incidence of metastatic spread)

If distinct- carcinoma may be localized


Not distinct- nice halo but broken in one spot (greater incidence of metastatic spread)

Ascites is an indication of what?

-cancer somewhere in the body

Why is a TV ultrasound most helpful in identifying endometrial carcinoma?

-showing myometrial invasion is clear evidence


-shown as thickening and irregularity of endo interface