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22 Cards in this Set

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  • Back
Vitamins for PMS (4)
1.) Calcium
2.) Magnesium
3.) Vitamin E
4.) Multivitamin
Calcium
a.) dosing
b.) effect on PMS
c.) caution
a.) 1200mg/day or 600mg twice daily
b.) decreases DEPRESSION, bloating, pain, fatigue, insomnia, food cravings
c.) can cause constipation, so avoid people with kidney stones
Magnesium
a.) dosing
b.) effect on PMS
c.) ADR
a.) 200-400 mg daily
b.) decreased bloating, breast tenderness
c.) DIARRHEA
Vitamin E
a.) dosing
b.) effect on PMS
a.) 400 IU during luteal phase
b.) mood, breast tenderness
Naproxen
220-250mg q6-8 hours
Ibuprofen
200-400mg q4-6 hours
Acetaminophen dosing
500-1000mg q4-6 hours
First line for bloating
Sodium restriction
2nd line for bloating
Pamabrom, a diuretic. Seen in pamprin, midol, etc
3rd line for bloating
Spironolactone diuretic
Oral contraceptives: Which is preferred?
Those that have drospirenone (Yaz, Yasmin, Beyaz, Safyral) bc it helps with mood (ant-androgen) and bloating (diuretic). Use biphasic or triphasic for 3-6 cycles
Danazol
Restrict use to SEVERE pms only. This causes amenorrhea
Leuprolide acetate
a.) class
b.) indication
a.) This is a GnRH agonist
b.) severe PMS (can worsen mood. dont use >6months). endometriosis
PMDD
a.) defining characteristic
b.) duration before defining
c.) when does it occur
a.) severe decreased mood that interferes with daily activity
b.) need to have symptoms (5+) for a year or more
c.) before your period (last week luteal)
1st line PMDD
SSRI's (PFS: Paroxetine, Fluoxetine, Sertraline), taken as needed (before period) or continuously
2nd line options (2) for PMDD
1.) SNRI (venlafaxine) or TCA (chlomipramine/anafranil)

2.) Birth control: Yaz & Beyaz. Other birth controls in general won't work for PMDD because birth control can worsen mood
Primary dysmenorrhea
a.) when does it occur?
b.) MOA
c.) risk factors
a.) this is painful period, so occurs DURING menstruation day 1
b.) too much prostaglandin release, resulting in stronger contractions, ischemia, sensitive nerves
c.) started early, heavy periods, long periods, smoking/alcohol, obesity
Primary dysmenorrhea- 1st line (2)
1.) NSAIDS: Ibuprofen 200-400mg q4-6h; Naproxen 225-250mg q8-12h
2.) Birth control
Secondary dysmenorrhea
a.) what
b.) symptoms
a.) This is dysmenorrhea due to an underlying disease (endometriosis, tumors, etc)
b.) very heavy bleeding than normal and lasts longer, no response to NSAIDs. refer to doctor
Endometriosis
a.) what
b.) risk factors
a.) When the endometrium grows outside of the uterus. Very painful periods or obstruction of periods, infertility
b.) never had kids, genetics, early start
Treatment for endometriosis - Nonpharm
SURGERY. Depends if patient wants to get pregnant or not. If she does want to get pregnant some day, do a conservative surgery, where they laproscopically remove the lesions. If she does not want to get pregnant, do a definitive surgery and take out the uterus or ovaries
Treatment for endometriosis - Pharm
NSAIDS or oral contraceptives (just like dysmenorrhea)