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9 Cards in this Set

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  • Back

bismuth subsalicylate (Pepto-Bismal)

Class: antidiarrheal, adsorbant


Indications: diarrhea


Dose: 30 mL or 2 tabs q 30-60 minutes (max 8 doses)


Adverse effects: aspirin based adverse effects, temporary darkening of tongue and stool


Contraindications: children or teens recovering from the flu or chicken pox, may cause Reye’s syndrome


Interactions: warfarin, aspirin, confusion in elderly


Administration: available OTC

diphenoxylate with atropine (Lomotil)

Class: antidiarrheal, opiate


Indications: diarrhea


Dose: 5 mg 3-4 times/day tapered to 25 mg 3-4 times/day


Adverse effects: abuse/dependence, extreme anticholinergic effects


Contraindications: diarrhea associated with pseudomembranous colitis or toxigenic bacteria


Interactions: other anticholinergic


Administration: oral use only

loperamide (Imodium A-D)

Class: antidiarrheal, opiate


Indications: diarrhea


Dose: 4 mg followed by 2 mg after a BM (max 16 mg)


Adverse effects: respiratory depression, urinary retention, constipation


Contraindications: severe ulcerative colitis, pseudomembranous colitis, acute diarrhea associated with e. Coli


Interactions: CNS depressants, opioids, sedative hypnotics, antipsychotics, skeletal muscle relaxants


Administration: OTC

glycerin

Class: hyperosmotic laxative


Indications: constipation


Dose: 1 suppository daily


Adverse effects: abdominal bloating, rectal irritation, electrolyte imbalances


Contraindications: allergy


Interactions: barbiturates, general anesthetics, opioids, antipsychotics


Administration: for children’s and adults

methylcellulose

Class: bulk forming laxative


Indications: constipation, irritable bowel syndrome, diverticulosis


Dose: 1 heaping tbsp in 8 ounces cold water daily-tid


Adverse effects: impaction above strictures, fluid disturbances, electrolyte imbalances, gas formation esophageal blockage, allergic reaction


Contraindications: GI obstruction, hepatitis


Interactions: antibiotics, digoxin, salicylates, tetracycline, warfarin


Administration: comes in powdered form

lactulose

Class: hyperosmotic laxative


Indications: constipation


Dose: 15-30 ml daily or bid


Adverse effects: abdominal bloating, rectal irritation, electrolyte imbalances


Contraindications: low lactose diets


Interactions: barbiturates, general anesthetics, opioids, antipsychotics


Administration: for oral or rectal use

docusate sodium (Colace)

Class: emollient laxative


Indications: constipation, anorectal conditions requiring facilitation of bowel movements


Dose: 50-300 mcg/day


Adverse effects: skin rashes, decreased absorption of vitamins, lipid pneumonia, electrolyte imbalances


Contraindications: intestinal obstruction, decal impaction, nausea, vomiting


Interactions: ?


Administration: simply softens stool

polyethylene glycol

Class: hyperosmotic laxative


Indications: GI lovage, total cleansing of bowel


Dose: 4L


Adverse effects: bloating, rectal irritation electrolyte imbalances


Contraindications: GI obstruction gastric retention, bowel perforation, toxic colitis, toxic mega colon, ileus


Interactions: barbiturates, general anesthetics, opioids, antipsychotics


Administration: patient must fast for 4 hours before drinking

senna (Senokot)

Class: stimulant laxative


Indications: acute constipation, bowel preparation for surgery or examination


Dose: max 4 tabs or 30 ml


Adverse effects: abdominal pain


Contraindications: appendicitis, obstructions


Interactions: antibiotics, digoxin, nitrofurantoin, salicylates, tetracyclines, anticoagulants


Administration: can produce BM in 6-12 hours