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399 Cards in this Set
- Front
- Back
First thing you look at in checking for Preggers
|
Last menstrual period
|
|
Chadwicks Sign
|
blue discoloration of cervix
|
|
Hegars sign
|
softening of the isthmus of the uterus
|
|
Goodells sign
|
Softening of the cervix
|
|
when can you begin to hear fetal heart
|
8 weeks
|
|
Naegeles Rule
|
add 9 mo and 7 days to LMP for due date
|
|
What can you see 5-6 weeks on US
|
gestational sac
|
|
What can you see 6-7 weeks on US
|
Fetal Pole
|
|
What can you see 7-8 weeks on US
|
Cardiac activity
|
|
what is the definition of Labor
|
Expulsion of products of conception resulting from regular uterine contractions and cervical changes
|
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False labor
|
contractions with no cervical change
|
|
Lightening
|
presenting part descends into pelvis
|
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4 stages of labor
|
"Onset of contractions to complete dilation of cervix
|
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what is pelvic station
|
presenting part in relation (cm) to the ischial spine (at level is 0, above is -, below is +)
|
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Effacement
|
obliteration of the cervical canal
|
|
Steps of delivery
|
"Internal Rotation
|
|
Pre eclampsia triad
|
"HTN
|
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Indication for C section
|
"preeclampsia
|
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placenta previa
|
placenta covers the cervix
|
|
tx of overactive bladder
|
detrol
|
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how does atrophic vagina cause incontinence
|
estrogen falls, vagina atrophies, pH goes up, UTI sets in
|
|
Definition of vaginitis
|
inflammation irritation or infection of the vagina
|
|
Etiology of vaginitis
|
"Infection
|
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3 most common infectious causes of vaginitis
|
"Bacterial vaginitis
|
|
Normal vagina
|
"pH 4-4.5
|
|
How do yeast and trichomoniasis infections relate to menstrual cycle
|
"Yeast is before menses
|
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what are you observing during the pelvic exam
|
Squamo-columnar junction- cancer, cervicitis, cervical motion tenderness
|
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If your pt has cervical motion tenderness what are you thinking she has
|
STDs- chlamydia and gonorrhea
|
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Tx for vaginitis
|
"Metronidazole- gel
|
|
Pt with normal vaginal pH and vaginitis
|
Candida
|
|
Tx of candida vulvovaginitis
|
"Diflucan- 1 time pill
|
|
Strawberry cervix"
|
Trichomoniasis
|
|
Tx for trichomoniasis
|
Metronidazole
|
|
5 things to think about in relation to pelvic mass
|
Age, Symptoms, organ of origin, location
|
|
Most common pelvic mass
|
"Myoma
|
|
Tests to perform for pelvic mass
|
HCG, CA125 (<35), MRI, CT, Laparoscopy
|
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What can infect skenes gland
|
chlamydida, gonnorhea
|
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Tx for fibroids
|
"childbearing age- remove fibroid
|
|
Where does most uterine enlargement occur during pregnancy
|
Fundus
|
|
Your patient wants advice on high impact exercise during pregnancy what do you tell her
|
up until 12 weeks the uterus is completely hidden in the pelvis and shouldnt be affected by impact
|
|
skin changes during preggers
|
Linea nigra, melasma gravidarum, angiomas and palmar erythema
|
|
where does most weight gain come from in preggers
|
uterus and its contents, breasts, 3rd space fluid
|
|
What are maternal reserves
|
increases in fat, protein and extracellular water
|
|
Normal pregnancy glucose status
|
Fasting hypoglycemia, post-prandial hyperglycemia, and hyperinsulinema
|
|
What is an important mineral to watch in pregnant women
|
"iron- Fe def anemia common
|
|
3 functions of pregnancy induced hypervolumemia
|
"Protect agains orthostatic BP changes
|
|
CBC changes in preg
|
"Dec hem and hct
|
|
CV changes
|
"HR increases by about 10
|
|
Increases in progesterone will affect
|
"respiratory effort will increase
|
|
kidney changes in preg
|
"BUN and Creat fall
|
|
most common location of ectopic preg
|
ampulla
|
|
Salpingectomy
|
removal of the fallopian tube
|
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Salpingostomy
|
Incision in the tube and remove the pregnancy
|
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High risk for ectopic preg
|
"TUbal surgery
|
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Ectopic triad
|
"Amenorrhea
|
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Dx ectopic
|
Presence of any non cystic extraovarian adnexal mass in the absence of intrauterin pregnancy (98% spec)
|
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Medical intervention of ectopic
|
Methotrexate
|
|
preferred tx for ectopic
|
"surgery
|
|
How do ovaries make estrogen
|
convert male hormones into estrogen
|
|
Commander of the hormones
|
GnRH
|
|
Kallman's Syndrome
|
"No sense of smell, no periods
|
|
what kills GnRH
|
Dopamine
|
|
Mechanism of turning on and off GnRH
|
adding/subtracting OH from dopamine (converting it to epi)
|
|
how do mitochondria factor into the menstrual cycle
|
needed to convert cholesterol into prenenolone (mother hormone)
|
|
what happens to pregnenolone
|
immediately converts into either progesterone or 17 hydroxypregnenolone
|
|
the 5 androgens
|
"testosterone
|
|
What hormone is a common stop in all steroids
|
Androstenedione
|
|
What 2 androgens have receptors
|
"Testosterone
|
|
Consequences of giving estrogen to post menepausal women
|
"Activates undetected breast cancer
|
|
What do granulosa cells do
|
"convert male hormones
|
|
What do inhibins do
|
"decreases FSH
|
|
Can thyroid hormone cross placenta
|
no
|
|
Thyroid Binding Globule levels in pregnancy
|
increase
|
|
What thyroid function test do you order in pregnant women
|
Free T4
|
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how does HcG relate to TSH
|
hCG acts like TSH in the weeks 10-12 and controls fetal thyroid
|
|
Importance of iodine in pregnancy
|
fetus needs to make own thyroid hormones, if mother is deficient, it cannot make them
|
|
Risks of a hypothyroid pregnant woman
|
preeclampsia, HTN, abruption of placenta, anemia, post partum hemorrhage and small gestational age of newborn
|
|
Risks to fetus in hypothyroid state
|
"impaired neural and somatic growth
|
|
Causes of maternal hypothyroid
|
"hashimoto
|
|
Dx maternal hypothyroid
|
"Free T4
|
|
TSH goal in pregnancy
|
2.5-4 mu/L
|
|
Tx for maternal hyperthyroid
|
"PTU- stops synthesis
|
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What is ectopic breast tissue
|
breast tissue that forms along the primative milk line, can develop into breast cancers
|
|
lots of plasma cells in GU tract"
|
"chancre from syphillis
|
|
Endarteritis
|
"inlammation of small blood vessels with plasma cell infiltration
|
|
scattered small abscess"
|
granuloma inguinale
|
|
Donovan bodies
|
"small rounded encapsulated bodies in histiocytes
|
|
bx: stellate abscess w pale epitheloid cells"
|
"Lymphogranuloma venereum
|
|
Behcet's
|
autoimmune, vasculitis in vulva
|
|
Vulvar Vestibulitis
|
"Chronic inflammation w lymphocyte infiltration
|
|
Bartholin cyst
|
"infection of bartholin gland (gonnorhea)
|
|
Vulvar Vestibularis
|
"Small glands in the vestibule become inflamed
|
|
Lichen Sclerosis
|
"Most common in elderly pop, if in children suspect abuse
|
|
Histology of lichen sclerosis
|
"atrophy of epidermis
|
|
Gross appearence of lichen sclerosis
|
white dry parchment like patches
|
|
Lichen simplex chronicus
|
"rubbing caused by puritits
|
|
Hidradenoma papilliferum
|
"can arise from ectopic breast tissue
|
|
Condyloma acuminata
|
"benign, branch like projections, fibrous stroma
|
|
VIN"
|
"premalignant
|
|
VIN- differentiated variant
|
"not hpv associated
|
|
Risks for vulvar cancer
|
"lots of sexual partners
|
|
Verrucous carcinoma
|
warty, large, exophytic lesion
|
|
extramammary pagets disease
|
"pruritic crust lesion with sharply demarcated lestion on labia majora
|
|
Aggressive angiomyxoma
|
"young women
|
|
VAIN"
|
"Squamous Cell
|
|
Clear Cell adenocarcinoma
|
"uncommon
|
|
histology of HSV cervicitis
|
multinucleated giant cells and intranuclear inclusions
|
|
Tunnel cluster
|
"proliferation of endocervical glands with side channels growing out
|
|
Microglandular hyperplasia
|
no atypia (diff from tunnel clusters)
|
|
Diffuse Laminar endocervical glandular hyperplasia
|
proliferation of medium sized evenly spaced well differentiated glands separated from the stroma
|
|
HPV infection
|
"infect immature basal cells or immature metaplastic squamous cells
|
|
oncogenesis with HPV
|
E6 and E7 proteins bind to Rb and upregulate cyclin E and interfere with p53
|
|
LSIL
|
"Low grade intrapithelial lesion
|
|
HSIL
|
"high grade intraeptithelial lesion
|
|
identifying CIN
|
staining KI-67 can identify HPV, lead you to SIL dx
|
|
most common malignant carcinoma of the cervix
|
invasive squamous cell carcinoma
|
|
sx of invasive squamous cell carcinoma of cervix
|
"at first asx
|
|
adenocarcinoma of cervix
|
"grossly similar to squamous
|
|
minimal diviation adenocarcinoma"
|
"not differentialed
|
|
adenosquamous carcinoma
|
"adenocarcinoma with well defined squamous component
|
|
Pearl Index
|
"how effective contraception is
|
|
Synthetic progestin OC
|
"induce endometrial atrophy
|
|
Ethinyl estradiol OC
|
suppress FSH, stabilized endometrium
|
|
higher risk of blood clots, OC or pregnancy
|
pregnancy
|
|
low dose OC
|
"no lower risk of DVT compared to 30/35 ug dose
|
|
benefit of 24 on 4 off compared to 21 on 7 off OC
|
24/4 is more effective, less risk of follicle recruit
|
|
Plan B
|
"Levonorgestrel
|
|
Gold standard for evidence collection for assault victims
|
DNA
|
|
Sources of evidence
|
Hair, Nail clippings, swabs, fibers, glass, clothing, all trauma
|
|
Signs of strangulation
|
contusions, fingernail marks, abrasions, ligature marks, hyoid fracture, petechiae, dusky brain
|
|
Dusky brain
|
cortical ribbon has dusky salmon color
|
|
amount of time to go unconcious from strangulation
|
10 sec
|
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key feature in court regarding strangulation
|
10 sec will knock out, trying to hurt person would be longer result in ptechiae and death (3 min)
|
|
Person dies from strangulation, no ptechiae
|
vagal stimulation resulting in disrhythmia
|
|
purpose of oxytocic agents
|
promote labor and delivery
|
|
Use of oxytocin
|
"Labor disorder
|
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Ergonovine and Methylergovine
|
increase rate and force of contractions
|
|
Prostaglandin Agents
|
"Stimulate uterine smooth muscle contractions
|
|
Dinoprostone
|
used for cervical ripening
|
|
use of tocolytics
|
uterine relaxants used for premature labor
|
|
Ritodrene
|
tocolytic, only IV, Beta2 and some beta1
|
|
What causes false negatives on PAP tests
|
Samping, screening, interpretation errors
|
|
When do you start screening for HPV
|
3 years after onset of vaginal intercourse or at age 21
|
|
Protocal for screening
|
"annual cytology or paps every 2-3
|
|
ASCUS
|
atypical squamous cells of undertermined significance
|
|
Managment of ASCUS
|
"can repeat pap or do colposcopy
|
|
Management of CIN
|
"repeat pap in 6 mo
|
|
ASCH
|
atypical squamous cells high risk
|
|
Management of ASCH
|
"repeat pap at 6 and 12 mo
|
|
Managment of HSIL
|
"LEEP
|
|
AGC
|
"atypical glandular cells
|
|
Management of AGC
|
"colposcopy
|
|
where do you find the squamo-columnar junction
|
moves around into the os and out varying with estrogen levels, post-menopause it retreats to the cervical canal, pregnant- found on ectocervix
|
|
How can you make cervical lesions appear more clearly
|
acetic acid
|
|
Lugol's solution
|
iodine solution, normal cells turn brown, abnormal cells lack glycogen and dont stain
|
|
What is mosaicism indicitive of in cervical lesions
|
vascularized lesion with capillaries
|
|
where are most lesions of the cervix
|
anterior lip
|
|
Peau d'orange
|
orange peel appearing cervix, abnormal blood vessels in the lesion
|
|
Most common ovarian cancer
|
"epithelial
|
|
most common GYN malignancy
|
"uterine
|
|
most lethal Gyn malignancy
|
ovarian cancer
|
|
Ovarian cancer risks
|
"BRCA
|
|
Pathogenesis of ovarian cancer
|
"Don't know
|
|
screening for ovarian cancer
|
"no good screen
|
|
managing ovarian cancer
|
surgery or chemo
|
|
chemo for ovarian cancer
|
carrboplatin, paclitaxel
|
|
Gram neg diplos
|
gonnorhea
|
|
where does gonnorhea infect in the female GU tract
|
endocervix and the fallopian tubes
|
|
one is a 8 yo boy one is a 8 yo girl, both have gram neg diplos on grm stain. what do you do"
|
"call social services for boy
|
|
How do you culture for gonnorhea
|
"thayer martin or chocolate media
|
|
gonorrheal syndromes
|
"urethritis
|
|
Tx for gonorhea
|
"ceftriaxone- DOC 125 mg IM
|
|
Dx syphilis
|
"dark field
|
|
tabes dorsalis
|
"widestance gait- neurosyphilis
|
|
#1 reason for false positive RPR
|
"pregnancy
|
|
Tx for syphilis
|
"2.4 MU PCN IM
|
|
Lymphogranuloma venereum
|
"chlamydia disease
|
|
Pediculosis Pubis
|
"crabs
|
|
Molluscum Contagiosum
|
"DNA virus
|
|
Endometrial hyperplasia
|
"premalignant
|
|
how do you determine type of hyperplasia (endometrium)
|
D and C
|
|
Simple hyperplasia without hyperplasia
|
"best one
|
|
simple hyperplasia with atypis
|
"loss of polarity
|
|
Complex hyperplasia without atypia
|
"crowded bizzare glands, branching, lots of mitosis, epithelium is actually normal
|
|
Complex hyperplasia with atypia
|
"overlaps with well differentiated adenocarcinoma
|
|
how does the endometrium progress to carcinoma
|
always step wise, simple hyperplasia- complex hyperplasia-complex atypical- CA
|
|
most common type of endometrial cancer
|
"carcinoma of the endometrium type 1
|
|
Endometroid Cancer
|
"PTEN, PIK3CA
|
|
How does the grading system of endometroid cancer work
|
"<5% solid mass G1
|
|
Carcinoma of the ENdometrium Type 2
|
"older population
|
|
Malignant Mixed Mullerian Tumor
|
"carcinoma and sarcoma
|
|
Most common benign tumor in females
|
leiomyoma aka fibroid
|
|
Morphology of leiomyoma
|
"well circumscribed grey white masses
|
|
when do leiomyoma progress to leiomyosarcoma
|
NEVER
|
|
Leiomyosarcoma
|
"Solitary, infiltrating, polyploid
|
|
TORCH
|
"toxoplasmosis
|
|
Placental infection
|
"ascending- more common
|
|
Chronic Villitis
|
"intrauterine growth retardation and stillbirth association
|
|
acute funisitis
|
"acute umbilical cord inflammation
|
|
placental infarct
|
"villous necrosis due to obstruction
|
|
gestational trophoblastic disease
|
Moles
|
|
Complete mole
|
"all paternal DNA
|
|
partial mole
|
"can see embryo (cant in complete)
|
|
invasive mole
|
"usually complete, villi go deep into myometrium
|
|
choriocarcinoma
|
"most aggressive gestational trophoblastic disease
|
|
placental site trophoblastic tumor
|
"rare
|
|
First thing you do when ob pt comes into office first time
|
verify pregnancy
|
|
how to calculate EDD
|
First day of LMP, minus 3 mo + 1 week
|
|
where should the fundus be at 20 weeks
|
umbilicus
|
|
When using US to determine due date what kind of freedom exists in believing pt hx or US
|
"1st trimester- 1 week
|
|
how do you determine gestational age using US
|
CRL
|
|
what additional nutrional requirements do pregnant women have
|
"only about 300-500 kcals more a day
|
|
what physical activities should be avoided during pregnancy
|
scuba diving, anything with lots of weight shifting (aerobics, change in center of gravity creates fall risk)
|
|
Prenatal labs
|
Pap, Gonorrhea, chlamydia, pelvic shape, Type (Rh), cbc, rubella, vdrl/rpr, hepatitis B, HIV, sickle cell, urine CS
|
|
1st trimester sequential screen
|
"11-14 weeks
|
|
Nuchal Translucency
|
"on saggital section US, the area behind the neck, fetus must be in neutral positioning
|
|
2nd trimester quad screen
|
risk for down, edwards, NT defects, AFP, HCG, Estriol and dimeric inhibin A
|
|
what does an abnormal AFP mean
|
"twins? then shes fine
|
|
labs showing neural tube defects
|
only AFP elevated
|
|
labs showing down syndrome
|
"dec AFP
|
|
Labs showing trisomy 18
|
"dec AFP
|
|
when is the best time to look at fetal anatomy via US
|
18-22 weeks
|
|
what defines IUGR
|
below 10th percentile in fetal weight
|
|
Fundal Height vs Gestational time
|
1 cm per week after 20 (umbilicus)
|
|
good fetal heart tones
|
"110-160 with accelerations
|
|
At what point does Rh factor start to become important
|
24-28 weeeks
|
|
when do you give a Rh- mother rhogam
|
24-28 weeks
|
|
When does the mom get a second dose of rhogam
|
postpartum if the baby is Rh+
|
|
Tests at Week 36
|
"Repeat all previous labs
|
|
What should labor be like in order to go to the hospital
|
1 every five minutes lasting about a minute each
|
|
Amniocentesis
|
"done at 16 weeks or neer term
|
|
Chorionic Villous Sampling
|
Done if discrepancy between size and gestational age, sign of placental insuffiency. deliver baby and keep in NICU
|
|
Method for kick counts
|
"lie on side for one hr. need 4+ kicks
|
|
Non Stress test
|
Should have 2 accelerations in FHR in 20 min period
|
|
What counts as an acceleration
|
"if 32+ weeks: 15 beats faster for 15 sec period
|
|
AFI
|
"amniotic fluid index
|
|
How does AFI factor into deciding whether to keep mother pregnant
|
if AFI is in range, can stay pregnant, if low and past or near due date should induce labor
|
|
Biophysical Profile
|
"if have non reative NST
|
|
when can you discharge post partum
|
"everything stable= 24-48 hrs
|
|
how long do post partum blues last
|
"2 weeks
|
|
Imitators of gyn pelvic pain
|
"intestine
|
|
Posture in pelvic pain
|
"anterior pelvic tilt
|
|
Normal N/V of pregnancy starts
|
"1st trimester
|
|
Definition of hyperemesis gravidarum
|
"persistant vomiting not related to other causes
|
|
What sx will HG NOT have
|
"Abd Pain
|
|
DDx for HG
|
"GI issue (almost any)
|
|
Hormone theories on HG
|
"hCG rises and falls along with N/V so possible link
|
|
Tx for N/V in pregnancy
|
"Multivitamin
|
|
Aging of the female reproductive tract
|
"starts at birth
|
|
Average age of natural menopause
|
"51
|
|
What defines a menopausal woman
|
12 consectutive mo of amenorrhea
|
|
How can menopause be induced
|
"surgical
|
|
what is early menopause
|
under 40, premature ovarian insufficiency
|
|
What can cause premature ovarian insufficiency
|
"idiopathic
|
|
how to dx premature ovarian insufficiency
|
age, 2 serial FSH levels a month apart are above 40 mIU/mL
|
|
What is perimenopause
|
3 years before FMP and 1 year after
|
|
sx of perimenopause
|
Vasomotor and vulvovaginal
|
|
Vasomotor sx of menopause
|
hot flashes night sweats
|
|
What is the cause of hot flashes
|
unknown
|
|
what are the vulvovaginal sx of menopause
|
"vaginal dryness
|
|
how do you tx mild VMS of menopause
|
"lifestyle mods
|
|
when should HT be started
|
"as close to actual menopause as possible
|
|
what is the difference between SGA and IUGR
|
"SGA is BIRTH weight under 10th percentile
|
|
Etiology of IUGR
|
"anything that disrupts flow of blood from mom to placenta to baby
|
|
Maternal causes of IUGR
|
anything that clamps down on vasculature
|
|
placental causes of IUGR
|
"1ary mosaicism
|
|
Fetal causes of IUGR
|
"inadequate or altered substrates
|
|
how does head/abd ratio change
|
head is larger than abd up til week 34, then should be 1, after that abd gets bigger
|
|
Management of IUGR
|
"lifestyle mods, diet, drugs, heparin
|
|
what do myometrial cysts imply
|
diffuse adenomyosis
|
|
endometrial CA on MRI
|
thick endometrial stripe
|
|
why does fetal heart rate slow down after 6-8 weeks
|
nervous system is forming an parasympathetics start regulating the heart rate
|
|
what is variable deceleration
|
"look like W and are a result of barometric receptors, increase in rate increase in pressure, slows down as reaction then goes back up w a slight overshoot
|
|
when are variable decels bad
|
last longer than 2 min and less than 10, keep your eye on it and maybe take resusitative measures
|
|
Early deceleration
|
nadir matches with contraction peak, usually head compression (vagal stime) and is benign
|
|
late decel
|
"concerning, onset to nadir is 30 sec with gradual return to baseline, occurs after contraction
|
|
variability
|
"a good thing, want a very jagged strip, shows baby is making adjustments in rate
|
|
when does cognition change during menstrual cycle
|
late luteal phase
|
|
progress of baby blues
|
5 days and tapering off over 2 weeks
|
|
the 3 parts of preconception care
|
protection, managing conditions, and avoiding exposures
|
|
how long should a woman wait between pregnancies
|
18-59 months
|
|
definition of infertility
|
"under 35 failure to concieve after a year
|
|
most common female factor in infertility
|
ovulatory dysfunction
|
|
Initial testing for infertility
|
"ovulation eval
|
|
menstrual cycle and infertility tests
|
"day 3- FSH test
|
|
indications for IVF
|
"tubal disease
|
|
after fertilization how long before you implant the eggs
|
3-5 days
|
|
benign breast masses
|
"cysts
|
|
what do cysts look like on US
|
Clear (fluid filled) single density well circumscribed
|
|
fibroadenoma
|
must be biopsied, well circumscribed and not fixed, clear with accoustic shadow
|
|
BI RADS system
|
"0- inconclusive
|
|
when is preterm birth
|
"20-37 weeks
|
|
PROM
|
"premature rupture of membrane
|
|
gold standard for endometrial cancer testing
|
DnC hysteroscopy or endometrial biopsy
|
|
Work up for endometrial cancer
|
biopsy, hysteroscopy, transvag US
|
|
tx for endometrial cancer
|
Surgery surgery surgery
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T score
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Bone dense compared to 35 yo
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z score
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bone density compared to same age
|
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where is bone density measured
|
hips and spine
|
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antiresorption meds for osteoporosis
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bisphosphonates, SERM
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Bone formation stimulant
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teripartide
|
|
placenta invades deep
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accreta
|
|
placenta goes into muscle
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increta
|
|
placenta goes thru the uterus
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percreta
|
|
what is the origin of innervation for the pelvic floor
|
anterior horn of the spinal cord called the onus nucleus
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T11- L1
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"sympathetics to kidneys
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T10- L1
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Upper ureter
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L1-L2
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Lower portion of ureter
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Innervation to the reproductive tract
|
"Sensory T12-S3
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3 steps in BLT
|
"Disengage- put in position of injury
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|
Turner Syndrome
|
"45x
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ovarian torsion
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"pedunculated ovaries
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follicular cysts
|
"unruptured graafian follicles
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Luteal cysts
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"physiologic
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Stein Leventhal Syndrome
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Polycystic Ovary Disease
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PCOD
|
"multiple cysts
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Pt with anovulation, obesity, hirsutism
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PCOD
|
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2nd sx of PCOD
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inc LH, inc Est, inc androgen, masculinization
|
|
Stromal hyperthecosis
|
"postmenopause
|
|
Most common type of ovarian tumors
|
surface epithelial
|
|
what age group are malignant ovarian tumors more common in
|
40-65
|
|
Risk factors for ovarian cancer
|
"nulliparity
|
|
Most common ovarian tumor
|
"serous surface epithelial tumor
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what is a borderline tumor
|
technically malignant, but hasnt invaded yet
|
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besides Ovarian cancer what can elevate CA125 levels
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any peritoneal irritation
|
|
Papillary formations filled with clear straw colored fluid
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serous ovarian tumor
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|
Most common malignant ovarian tumor
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serous adenocarcinoma
|
|
mucinous ovarian tumor
|
"cystic, bilateral, middle adults, mostly benign or borderline
|
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Endometrioid tumor of the ovary
|
"good prognosis
|
|
Clear cell carcinoma of the ovary
|
"premenopausal- 40-50
|
|
hobnail cytoplasm
|
clear cell carcinoma of the ovary
|
|
cystadenofibroma
|
"cyst, glandular, and fibrotic component
|
|
Coffee bean like nuclei
|
brenner tumor
|
|
Brenner tumor
|
"cells look like transitional cells
|
|
Acute Mastitis
|
"only associated with lactation
|
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Duct ectasia
|
"older F, lots of pregnancy
|
|
Granulomatous Mastitis
|
"rare, dx of exclusion
|
|
Benign non proliferative dz
|
"Fibrocystic
|
|
Fibrocystic Change
|
"25-45 whites
|
|
Nonproliferative vs proliferative fibrocystic change
|
"Nonprolif- apocrine snouting, single layer
|
|
school of fish appearence of epithelial cells
|
Florid duct hyperplasia
|
|
Looks like a glomerulus
|
florid duct hyperplasia
|
|
atypical duct hyperplasia
|
"lose streaming appearance
|
|
DCIS
|
Precursor to breast cancer
|
|
Roman bridges
|
DCIS
|
|
How do you tell when DCIS has progressed to ductal carcinoma
|
loses myoepithelial layer
|
|
Atypical lobular hyperplasia
|
"raises cancer risk
|
|
Intraductal Papilloma
|
"bloody nipple discharge
|
|
Lactating adenoma
|
"reprod age
|
|
Stromal tumor
|
"found in preggers (gets bigger)
|
|
who do you test for BRCA
|
"ashkenazis
|
|
most common location for breast cancer
|
upper lateral quadrant
|
|
most common invasive breast cancer
|
Ductal Carcinoma
|
|
puckering of breast tissue
|
Ductal Carcinoma
|
|
Appearence of ductal carcinoma in pleural fluid
|
"cannonball, Ecadherin makes them stick together
|
|
LCIS
|
does not have ecadherin and has bridging lesions
|
|
Lobar Carcinoma
|
"high rate of bilateral
|
|
Tubular Carcinoma
|
"well differentiated
|
|
Mucinous carcinoma
|
"well circum
|
|
medullary carcinoma
|
"very common
|
|
Invasive papillary carcinoma
|
"papillary projections
|
|
Inflammatory Breast cancer
|
"peau de orange
|
|
Paget's disease
|
"inflammatory appearence
|
|
malignant phylloides tumor
|
"very aggressive
|
|
angiosarcoma of the breast
|
post radiation for breast cancer
|
|
Breast cancers with favorable prognosis
|
"tubular
|
|
Breast cancers with poor prognosis
|
"signet ring
|
|
Distinguish DCIS from atypical ductal hyperplasia
|
DCIS has necrosis
|
|
Mature teratoma
|
"most common teratoma
|
|
monodermal teratoma
|
one predominant tissue type, can have sx related to that tissue
|
|
struma ovarrii
|
thyroid tissue, might have hyperthyroidism
|
|
immature teratoma
|
"seen in young population
|
|
dysgerminoma
|
"bulky soft fleshy yellow
|
|
endodermal sinus tumor
|
"aka yolk sac
|
|
choriocarcinoma
|
placental origin, aggressive to LLB,
|
|
granulosa theca tumor
|
"postmenapause
|
|
Call exner bodies
|
"neoplastic cells producing gland like structure
|
|
Paraneoplastic effects of granulosa theca cell tumors
|
produce lots of estrogen, inhibin
|
|
Fibroma-Thecoma
|
"unilateral solid mass, hard, grey white, has intact serosa
|
|
Meige Syndrome
|
"Ascites, Hydrothorax, Rt sided pleural effusion, increased abd girth
|
|
Sertoli-Leydig Cell tumor
|
"20-30s
|
|
Krukenberg Tumor
|
"most common met to ovary
|
|
How does blood volume increase in pregnancy
|
chorionic blahblahblah stims renin, renin stims angio1->angio2->aldosterone increase Na... increase
|
|
how does BP stay the same as CO rises to compensate for decrease hct
|
SVR drops because blood is shunted to the placenta and baby, a low resistance system
|
|
why does bp rise towards the end of pregnancy
|
baby and placenta begin to have resistance to be ready for birth
|
|
trend of CO during pregnancy
|
increases all the way
|
|
trend for BP during preg
|
lowers then rises
|
|
3 catagories for all troublesome heart conditions during pregnancy
|
"Left ventricular function
|
|
How can you quickly test a pts left heart function
|
PMI, should be the size of a finger pad
|
|
Sound of the heart with stenosis
|
no S2
|
|
Real heart problems during preg
|
"aortic stenosis
|
|
Drugs to manage heart in preg
|
"NONE
|
|
definition of preeclampsia
|
"HTN after 20 weeks
|
|
Severe preeclampsia
|
"5 grams on 24 hr urine
|
|
HELLP syndrome
|
"hemolysis
|
|
higher incidence of preeclamp in
|
"twins
|
|
widely used tx for preeclamp
|
mag so4
|
|
what diuretic used in preeclamp
|
"nooooone dont do it
|
|
best drug for preeclamp
|
"labetolol... only if you really really need it tho
|