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62 Cards in this Set

  • Front
  • Back

is an ecological relationship between two different species that live together in direct contact

symbiosis

is a symbiotic relationship where both organisms benefit, like endosymbiosis, or human gut microbes

Mutualism

is a symbiotic relationship where one organism benefits and the other is neither harmed nor helped

Commensalism

is the collection of bacteria, fungi, and archaea that lives on and in the skin, in the gastrointestinal tract, in the mouth, in saliva, and in the conjunctiva of the eye

The human microbiota

is a symbiotic relationship where one organism benefits at the expense of the other, like viruses, pathogenic bacteria, and worms

Parasitism

A parasite that lives on the host and feeds on cell components, tissues, or body fluids

(ectoparasite)

A parasite that lives inside the host and feeds on cell components, tissues, or body fluids or inside

endoparasite

is a disorder of the structure, function, or biochemistry of an organism or part of an organism

Disease

is the study of the causes of disease, while virulence is the degree of pathogenicity

Pathology

chronic diseases due to genetic factors, aging, behavior, exposure to chemicals like

Non-communicable diseases

The result of living agents developing and multiplying in body of host like bacteria, viruses, and fungi

Infectious diseases

is something that causes infectious disease

pathogen

is the potential for a pathogen to cause disease




(qualitative)

Pathogenicity

the degree of pathogenicity




(quantitative)

Virulence

how pathogens are transferred from host to host and can be vertical or horizontal

Transmission

Four criteria that were established to identify the causative agent of a particular disease, these include:


the microorganism or other pathogen must be present in all cases of the disease


the pathogen can be isolated from the diseased host and grown in pure culture


the pathogen from the pure culture must cause the disease when inoculated into a healthy, susceptible laboratory animal


the pathogen must be reisolated from the new host and shown to be the same as the originally inoculated pathogen

Kock's postulate

Horizontal transmission via GI tract

Fecal -Oral:

Horizontal transmission via respiratory tract: coughing, sneezing, touch

Respiratory:

Horizontal transmission via: wounds, insect bites, blood transfusions , placenta, IV drugs, sexual. Sexual: via genitourinary tract:

Blood-borne

Horizontal transmission : via fomites (inanimate objects) e.g. soil, rusty nails

Contact

is a person, animal, or microbe that carries and transmits an infectious pathogen

vector

: Arthropod carries pathogen on feet

Mechanical transmission

Pathogen reproduces in vector

Biological transmission

____Vectors are common such as fleas, ticks, and mosquitoes

Arthropod vectors

Disease occurs at rates higher than expected

Epidemic:

Disease exists at a low/expected rate

Endemic:

: More than one continent and rates higher than expected

Pandemic

are subjective like pain and malaise

Symptoms

are objective like fever, rash, and paralysis

Signs

The__________ is the time between exposure and the onset of symptoms

incubation period

The_________is the time between exposure and communicability

latent period

symptomatic; mild to severe

Clinical infection:

asymptomatic, may be a chronic or latent infection, incubation period

Subclinical infection:

: rapid onset, obvious signs & symptoms, body able to eliminate quickly

Acute infection

: may be without obvious signs & symptoms, body unable to eliminate quickly; may last years

Chronic infection

inactive for long periods, e.g. herpes simplex

Latent infection:

: healing time - may or may not be contagious

Convalescence

- source of infection for others; often asymptomatic e.g. prolonged shedding of virus in feces or saliva during convalescence

Carriers

contagious;

Communicable:

: not contagious

Non-communicable

pathogen spread throughout the body

Systemic infection:

: confined to a small part of the body

Local infection

: presence and multiplication of pathogens in blood

Septicemia

presence but not multiplication in blood

Viremia, bacteremia:

follows (result of) primary infectionE.g. Flu followed by bronchitis

Secondary infection:

: only small percentage infected develop symptoms, e.g. poliovirus

Iceberg Concept

_______is the study of all factors regarding occurrence of a disease such as:


Entry - explosive/mild; winter/summer; earthquake/floods


Appears - who is stricken; children/men/women/profession


How spread - vectors or animals


Fluctuations or cycles


How it recedes and disappears

Epidemiology

A ________ is a source of an infectious agent


Soil, water: tetanus, hepatitis A


Animals: rodents and fleas in bubonic plague


Humans: AIDS, gonorrhea, typhoid fever

reservoir of infection

is the sum of the factors that come together to cause non-communicable and infectious diseases. It’s the causes of disease

Etiology

First case of a disease to be identified and reported




Source of the infection for the community

Index case:

: conducted in the present, during outbreak


Number of cases, location and geographic distribution, segment of the population affected, serological surveys - antibodies to infection

Prospective studies

: conducted after the fact

Retrospective studies

A ______is an infectious disease of animals that can be naturally transmitted to humans.

zoonosis

(number of deaths)

Mortality rate

(number of illnesses)




Number of cases within a specified time period/population size in which cases occurred times 1000 or 100,000

Morbidity rate

one person to another

Horizontal transmission:

mother to unborn or nursing child

Vertical transmission:

: % immune to infection If high, # of new cases will be low If low, # new cases will be high

Herd immunity

hospital acquired infections

Nosocomial infections:

_____ is the joint evolution of two interacting species, each in response to selection imposed by the other




It can occur at the species level or the molecular level




It can occur in predator/prey, host/parasite, and mutualistic relationships

Co-evolution

Epithelial surfaces such as mouth, eyes, nose, respiratory tract, GI tract, anus, genitourinary tract: vagina, urethra

Portals of entry

are cell surface components that allow adherence to surfaces or other cells

Adhesins