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28 Cards in this Set

  • Front
  • Back

Psychpharmacology

The use of medications to treat mental illness.

Efficacy

Refers to the maximal therapeutic affect that a drug can achieve.

Potency

Describe the amount of the drug needed to achieve that maximum effect; low potency drugs require higher dosages to achieve efficacy, while high potency drugs achieve efficacy at lower dosages.

Half-life

The time it takes for half of the drug to be removed from the bloodstream.

Off-label Use

A drug will prove effective for a disease that differs from the one involved in original testing and FDA approval.


And example is some anti-convulsant drugs (approved to prevent seizures) that are prescribed for the effects and stabilizing the moods of patience with bipolar disorder.

Black Box Warning

When I drug is found to have serious or life-threatening side effects; the package inserts must have a highlighted box, separate from the text, which contains a warning about the serious or life-threatening side effects.

Rebound

Temporary return of symptoms.

Recurrence

Recurrence of original symptoms.

Withdrawal

New symptoms resulting from discontinuation of the drug.

Antipsychotic Drugs

A.K.A. Neuroleptics


Used to treat the symptoms of psychosis, such as delusions and hallucinations seen in schizophrenia, schizoaffective disorder, and the manic phase of bipolar disorder.

Conventional or first generation antipsychotics

Phenothiazines


Chlorpromazine (Thorazine)


Perphenazine (Trilafon)


Fluphenazine (Prolixin)


Thioridazine (Mellaril)


Mesoridazine (Serentil)


Trifluoperazine (Stelazine)


Thioxanthene


Thiothixene (Navane)


Butyrophenones


Haloperidol (Haldol)


Droperidol (Inapsine)


Dibenzazepine


Loxapine (Loxitane)


Dihydroindolone


Molindone (Moban)

Atypical or second generation antipsychotics

Clozapine (Clozaril)


Fazaclo (clozapine)


Risperidone (Risperdal)


Olanzapine (Zyprexa)


Quetiapine (Seroquel)


Ziprasidone (Geodon)


Paliperidone (Invega)


Iloperidone (Fanapt)


Asenapine (Saphris)


Lurasidone (Latuda)

Third generation antipsychotics

Aripiprazole (Abilify)


Cariprazine (Vraylar)


Brexpiprazole (Rexulti)

Extrapyramidal Side Effects

Serious neurological symptoms. Major side effects of antipsychotic drugs.


These include:


Acute dystonia (acute muscular rigidity and cramping)


Pseudoparkinsonism (drug induced Parkinsonism)


Akathisia (intense need to move about)

Drugs used to treat Extrapyramidal side effects

Amantadine (Symmetrel)


Benztropine (Cogentin)


Biperiden (Akineton)


Diazepam (Valium)


Diphenhydramine (Benadryl)


Lorazepam (Ativan)


Procyclidine (Kemadrin)


Propranolol (Inderal)


Trihexyphenidyl (Artane)

Neuroleptic Malignant Syndrome (NMS)

A potentially fatal idiosyncratic reaction to an antipsychotic drug.


S/S: Rigidity, high fever, unstable BP, diaphoresis, pallor, and delirium.

Stimulant Drugs

Primary use is for ADHD in children and adolescents, residual attention deficit disorder in adults, and narcolepsy.

Stimulants

Methylphenidate (Ritalin)


Sustained release (Ritalin-SR)


Transdermal patch (Daytrana)


Dextroamphetamine (Dexedrine)


Sustained release (Dexedrine SR)


Amphetamine (Adderall)


Sustained Release (Adderall SR)


Permoline (Cylert)


Selective norepinephrine reuptake inhibitor:


Atomoxetine (Strattera)

Disulfiram (Antabuse)

Never give to a client instead of alcohol intoxication or without the clients full knowledge. Instruct the clients relatives accordingly.

Tardive Dyskinesia

A syndrome of permanent involuntary movements.


Most commonly caused by the long term use of conventional antipsychotic drugs.

Antidepressant Drugs

Primarily used in the treatment of major depressive illness, anxiety disorders, the depressed phase of bipolar disorder, and psychotic depression.

Selective serotonin reuptake inhibitors

Fluoxetine (Prozac)


Fluvoxamine (Luvox)


Paroxetine (Paxil)


Sertraline (Zoloft)


Citalopram (Celexa)


Escitalopram (Lexapro)

Cyclic Compounds

Imipramine (Tofranil)


Desipramine (Norpramin)


Amitriptyline (Elavil)


Nortriptyline (Pamelor)


Doxepin (Sinequan)


Trimipramine (Surmontil)


Protriptyline (Vivactil)


Maprotiline (Ludiomil)


Mirtazapine (Remeron)


Amoxapine (Asendin)


Clomipramine (Anafranil)

Monoamine Oxidase Inhibitors

Phenelizine (Nardil)


Tranylcypromine (Parnate)


Isocarboxazid (Marplan)

Other Antidepressant Drugs

Bupropion (Wellbutrin)


Venlafaxine (Effexor)


Desvenlafaxine (Pristiq)


Trazodone (Desyrel)


Nefazodone (Serzone)


Duloxetine (Cymbalta)


Vilazodone (Viibryd)

Mood Stabilizing Drugs

Used to treat bipolar disorder by stabilizing the clients mood, preventing or minimizing the highs and lows that characterize bipolar illness, and treating acute episodes of mania.


Lithium

Anxiolytic Drugs

Treat anxiety and anxiety disorders, insomnia, OCD, depression, PTSD, and alcohol withdrawal.

Anti-anxiety (Anxiolytics) Drugs

Benzodiazepines


Alprazolam (Xanax)


Chlordiazepoxide (Librium)


Clonazepam (Klonopin)


Clorazepate (Tranxene)


Diazepam (Valium)


Flurazepam (Dalmane)


Lorazepam (Ativan)


Oxazepam (Serax)


Temazepam (Restoril)


Triazolam (Halcoin)


Nonbenzodiazepines


Buspirone (BuSpar)