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18 Cards in this Set

  • Front
  • Back
"Pill Cervix"
microglandular hyperplasia (Progesterone effect)
What 2 bugs may cause acute cervicitiis?
gonococcus or chlamydia
High risk types of HPV that is found in precacnerous cervical mucosa
HPV virus in condyloma accuminatum and warts reamain ____
___ oncoprotein product of HPV binds with and degrades p53; _____ oncoprotein binds hypophosphorylated pRb,
frees E2F transcription factor to drive cell cycle
E6; E7
HPV infected cells; nuclear size, N/C, irregular nuclear contours, hyperchromasia and perinuclear clearing
CIN III also called what?
Carcinoma in situ
Where do cervical lesions begin?
Transformatino zone (squamo-columnar jxn)
iodine (Schiller’s) test—stains glycogen in normal cells for dx
Cervical cancer (Done before we had a good colposcopy:use acetic acid and bx technique)
Stage 0 of Invasive cervical cancer
Stage 1 of Invasive Cervical Carcioma
limited to cervix
Stage 2 of Invasive Cervical Carcioma
Beyond cervix upper 1/3 vagina, does not reach pelvic wall
Stage 3 of Invasive Cervical Carcioma
lower 1/2 vagina & reaches pelvic wall
Stage 4 of Invasive Cervical Carcioma
beyond pelvis or invaded bladder or colon; distant metastases
Where is cervical cancer likely to met?
uterers, colon and bladder
Nabothian cysts
squamous metaplasia of endocervical mucosa (Chronic cervicitis)
MC Types of HPV found in high grade cervical lesions
16 and 18 (31,33,35 too, but not as often)
Types of HPV MC in condylomas
6 and 11