Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
What is Gout?
|
Inflammatory disease of peripheral joints caused by monosodium urate crystal deposits
|
|
|
What is the difference between primary and secondary gout?
|
Primary gout is d/t inborn error in production or excretion of uric acid
Secondary gout can develop d/t another disease (leukemia, MDS, renal insufficiency) or as a result from certain drugs (salicylates, diuretics, nicotinic acid, alcohol) Secondary can also be induce from a diet high in purines (anchovies, organ meats, liver, spinach, mushrooms, asparagus, oatmeal, cocoa, sweetbreads) |
|
|
Which joint is typically affected with an acute attack of gout?
|
MP joint of the big toe (Podagra)
|
|
|
S&S of an acute gout attack
|
Sudden onset of joint inflammation and excruciating pain
Signs include warm, tender, erythematous joint and possibly fever |
|
|
What is Tophi?
|
chalky deposits of sodium urate
Tophi seldom become visible until 10 years after the onset of gout |
|
|
What lab value is usually sufficient to establish a dx of gout?
|
hyperuricemia
|
|
|
TX of acute gout
|
NSAIDS
Steriods colchinine |
|
|
TX of chronic gout
|
urate lowering agents
|
|
|
When would you start a urate lowering medication after an acute attack and why
|
2-4 weeks becaused it may worsen sx
|
