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3 Cards in this Set
- Front
- Back
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What virulence factors are produced by Streptococcus pyogenes? |
- streptolysins: lyse RBCs and toxic to neutrophils - M proteins: external to cell wall, allow adherance and immune system avoidance. Promotes pathogenesis. - hyaluronidase: dissolves connective tissue (hyaluronic acid) - streptokinases: dissolve blood clots |
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How do M proteins help Streptococcus pyogenes colonize/infect the host? |
- prevents activation of complement - evades phagocytosis - helps adhere to mucosal membranes |
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What 2 things can Streptococcus pyogenes cause? |
- necrotizing fasciitis: flesh eating disease, destroys tissue rapidly - streptococcal toxic shock syndrome: similar to staphylococcal TSS but much worse. |
