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43 Cards in this Set
- Front
- Back
System of glands that secrete hormones |
Endocrine system |
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What’re the 3 types of hormones |
Peptide, steroids, and amino acids |
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Made from large, precursor polypeptides from post-translational modifications |
Peptide hormones |
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Peptides work by utilizing what kind of messenger system? |
Second messenger |
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Function of peptide hormone? |
Bind to a receptor (1st messenger) to trigger the release of another hormone (2nd messenger) |
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T/F: one hormone can bind many receptors before degradation? |
True |
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Common 2nd nessengers |
cAMP, IP3, Ca2+ |
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Peptides hormones are great in short doses, but why? |
They take effect very rapidly and are easy to control, however, they degrade extremely fast. |
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Are peptide hormones lipid soluble or water soluble? |
Water soluble; they can freely travel through blood without carriers |
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What are steroids hormones derived from? |
Cholesterol |
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Cholesterol is a |
Non polar molecule that can cross the plasma membrane |
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Steroid hormones need a _______ black to carry them due to their __________. |
Protein; hydrophobicity |
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Where are steroid hormones? |
Intracellular |
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Which hormones can directly increase or decrease the transcription of certain genes? |
Steroid |
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List the amino acid derived hormones |
Epinephrine Norepinephrine Thyroxine |
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What receptors do catecholamines bind to? |
GPCR |
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Where do thyroids hormones bind? |
Intracellularly |
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Hormones that are secreted and act directly on target tissue |
Direct hormones |
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Hormones that are secreted and act directly on target tissue |
Direct hormones |
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Hormones that require an intermediate or other source to activate the hormone to be released |
Tropic hormone |
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Example of tropic hormone |
GnRH—-> LH/FSH—-> estrogen/testosterone |
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Organ in the brain that connects the nervous system and endocrine system |
Hypothalamus |
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What organ does the hypothalamus control and how? |
The pituitary through paracrine release |
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What organ does the hypothalamus control and how? |
The pituitary through paracrine release |
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How are the hormones of the pituitary regulated? |
Negative feedback |
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What organs hormones are rarely, if ever, found in the bloodstream? |
Hypothalamus |
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What organs hormones are rarely, if ever, found in the bloodstream? |
Hypothalamus |
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The anterior pituitary secretes components from the hypothalamus into |
The hypophyseal portal system |
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Which hormone is dopamine an antagonist of? |
Prolactin |
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Mnemonic for hormones secreted by the anterior pituitary |
FLAT PEG Tropic vs Direct |
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What hormones are secreted by the posterior pituitary? |
Oxytocin and ADH |
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ADH is secreted in response to |
Higher solutes in the blood or low blood volume |
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Growth factor grows bone and muscle. Which hormone works in a positive feed back loop to aid this |
Oxytocin |
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Growth factor grows bone and muscle. Which hormone works in a positive feed back loop to aid this |
Oxytocin |
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Thyroid secretes |
Thyroxine (T4) and triiodothyronine (T3) |
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Thyroid secretes which mineral? |
Increase calcium storage in bone; increase calcium excretion by the kidney; decrease calcium absorption by the gut |
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Hypothyroidism is caused by |
Iodine deficiency |
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Hypothyroidism is caused by |
Iodine deficiency |
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Hyperthyroidism is caused by |
Excess iodine |
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PTH is the antagonist of _________. PTH serves to decrease bone calcium and activate ___________, a derivative of vitamin D. |
Calcitonin; calcitriol |
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Where is the adrenal glands found? |
Top of kidneys |
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Aldosterone functions to |
Increase sodium reabsorption in the distal convoluted tubules and collecting duct |
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Tyrosine derivatives are |
Thyroid (steroids that aren’t derived from cholesterol) Catecholamines (peptides) |