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15 Cards in this Set

  • Front
  • Back

Neosporin (bacitracin, neomycin, and polymyxin B)

Inhibits and kills staph or strep organism (+)


Treatment and prevention of minor skin wounds

Mupirocin (bactroban)

Indication: impetigo, infected skin lesions, inhibits protein synthesis.


Silver sufadiazine (silvadene)

Prevention and treatment of infection in partial and full thickness burns.


Increases potential for drug absorption due to impairment of the skin

Antifungal agents

Meds: clotrimazole (lotrimin)


Minconazole (monistat)


Nystatin (mycostatin)


Affects synthesis of fungal cell wall.

Ectoparasiticidal drugs (scabies and lice)

OTC: pyrethrins with piperonyl bitoxide (RID)


Permethrin 1% (Nix)



RX:


Permethrin cream 5% (elimite)


Crotamiton (eurax)


Malathion (ovide)

Skin prep

Isopropyl alcohol


Povidone-iodine (betadine)


Chlorhexidine (hibiclens)

Sulfonamides

MOA: bacteriostatic and focus acid inhibitors.


Indication: broad spectrum organisms, UTI, pneumocystis jirovecii.

Beta-lactate antibiotics (penicillin, cephalosporins, and carbapenems

MOA: PCN binding protein sites inside bac. Wall. Inhibit bac. Wall cell synthesis.


Indication: gram (+) organism



Macrolides: azithromycin (zithromax), clarithromycin (biaxin), and erythromycin

MOA: protein synthesis inhibitor.


Indication: group A beta-hemolytic strep., Lyme's disease. Gastric ulcers, STI.


Interactions: carbamazepines, digoxin, warfarin

Tetracycline and doxycycline

MOA: protein synthesis inhibitors


Indication: gram (+) and (-) , STIs, acne.


Contraindicated: pregnancy, breast feed, children <8


Interactions: antacids, dairy, enthral feedings, iron products

Aminoglycosides: gentamycin and neomycin

MOA: protein synthesis inhibitor


Indication: serious gram (-) infection, bacterial endocarditis gram (+)


Contraindicated: pregnancy and breast feeding.


Interactions: nephrotoxic drugs,loop diuretics

Quinolones: ciprofloxacin and levofloxacin

MOA: alters DNA by interfering with gyrase and topoisomerase enzymes.


Indication: gram (-), cystic fibrosis resp. Infection.


ADE: ruptured tendons (black box warning), thrush.

Clindamycin (cleocin)

MOA: protein synthesis inhibitors


Indication: gram (+) bacteria, pseudomembranous colitis

Metronidazole (flagyl)


MOA: inhibits DNA synthesis


Indication: anaerobic ABD and GYN infections.


Interactions: alcohol

Vancomycin

MOA: adheres to bacterial cell wall producing death.


-trough levels


ADE : red man syndrome