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86 Cards in this Set
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True |
Pharmacognosy literally means the knowledge of drugs or pharmaceuticals. True or False? |
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Pharmacognosy |
It is also defined as an applied science that deals with the biologic, biochemical and economic features of natural drugs and their constituents originated from plants and animals. |
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Crude |
Pharmacognosy is the study of ______ drugs. |
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Dioscorides |
•Greek Physician •Wrote De Materia Medica in 78 A.D. |
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De Materia Medica |
This consists of about 600 plants described by Dioscorides that were known to have medicinal properties. |
78 A.D. |
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Galen |
•Greek Pharmacist-Physician •Lived in Rome •Described the method of preparing formulas known to have medicinal properties |
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False |
Crude drugs are fruits or animal drugs that consists of natural substances that have not undergone only the process of collection and drying. True or False? |
Vegetables; that have undergone |
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Crude Drugs |
These are any products that have not been advanced in value or improved in condition by shedding, grinding, chipping, crushing, distilling, evaporating, extracting, artificial mixing with other substances. |
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Natural Substances |
These are found in nature that comprise the whole plants and herbs and anatomic parts thereof. |
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C |
These are examples of natural substances, except: A. Sap B. Extracts C. Bark D. Secretions E. Whole Animals F. Animal Organs |
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ABCEF |
Process of preparing drugs for commercial market: A. Collection B. Harvesting C. Drying D. Extracting E. Garbling F. Packaging, storage, preservation |
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ABCDFG |
Effects of moisture associated with improper storage and preservation: (Choose all that apply) A. ⬆ weight of drug B. ⬇ percentage of act. const. C. Favors enzymatic activity D. Facilitates fungal growth E. ⬆percantage of act. const. F. Highly colored drugs G. Undesirable changes in const. |
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True |
Effects of air associated with improper storage and preservation increases oxidation of the const. of the drugs. True or False? |
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65 C |
For the protection of frugs against attacks by insects, expose the drug to a temperature of ______. |
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Methyl bromide |
For the fumigation of large lots of drugs, use ______. |
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Tight, light-resistant containers |
For small lots of drugs, store in : |
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Organoleptic, microscopic, biologic, chemical, physical |
Different methods of evaluating drugs (5) |
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Morphologic, Taxonomic, Therapeutic/Pharmacologic, Chemical |
Classification of drugs (4) |
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Inert/inactive constituents |
They have no definitive pharmacologic activity. Their presence sometimes prevent the absorbability or potency of the active constituents. |
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Active Constituents |
They are responsible for the therapeutic effect. |
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Pharmaceutically active |
These are constituents that may cause precipitation or other chemical changes in a medicinal preparation. |
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Pharmacologically active |
These are constituents that are responsible for the therapeutic activity of the drug, it's eaither single chemical substances or mixtures of principle. |
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C |
The ff statements about Carbohydrates are true, except: A. It is the major source of energy B. It is the most abundant biomolecule on earth C. It is the secondary source of energy for all living organism D. Serves as structural components E. They are aldehydes or ketones containing CHO F. First products formed in photosynthesis |
It is the MAIN source of energy |
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Sugars, polysaccharides |
Classification of carbohydrates (2) |
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Monosaccharides |
These are compounds that cannot be hydrolyzed to simple sugars. |
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Disaccharides |
Yields two monosaccharide molecules on hydrolysis. |
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Trisaccharides |
Yields three monosaccharide molecules on hydrolysis. |
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Tetrasaccharides |
Yields four monosaccharide molecules on hydrolysis. |
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Monosaccharide |
•simple sugars •smallest unit that make up carbohydrates •building blocks |
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Glucose, Galactose, Fructose |
Three main monosaccharides in the human diet. |
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C |
Other names of glucose, except: A. D-glucose B. Blood sugar C. Milk sugar D. Dextrose E. Corn sugar F. Grape sugar |
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False |
Glucose appears in the urine in gestational diabetes. True or false? |
Appears in Diabetes mellitus |
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Glucose |
It is an aldohexose obtained by controlled enzymatic hydrolysis of starch. |
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True |
Aka milk sugar, galactose is less sweet than glucose. True or false? |
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Galactose |
It is synthesized in the body where it is formed associated with glycolipids and glycoproteins. It is also a component of lactose and other oligosaccharides, cerebrosides and gangliosides, glycolipids and glycoproteins. |
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A |
Other names of Fructose, except: A. Blood sugar B. Fruit sugar C. Levulose D. Hexulose E. D-fructose F. D-arabino G. D-fructofuranose |
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Fructose |
•It is absorbed directly into the bloodstream during digestion •most water-soluble of all the sugars |
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Disaccharides |
It is a carbohydrate which is formed when 2 simple sugars undergo condensation rxn which involves the elimination of a small molecule such as water from the functional group. |
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Sucrose, Lactose, Maltose |
Most common disaccharides (3) |
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A |
Other name of sucrose: A. Table Sugar B. Milk Sugar C. Malt sugar |
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B |
Other name of lactose:A. Table SugarB. Milk SugarC. Malt sugar |
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C |
Other name of maltose:A. Table SugarB. Milk SugarC. Malt sugar |
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A |
Which of these are the monosaccharides that combine to make sucrose? A. Glucose+Fructose B. Glucose+Galactose C. Glucose+Glucose |
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B |
Which of these are the monosaccharides that combine to make lactose?A. Glucose+FructoseB. Glucose+GalactoseC. Glucose+Glucose |
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C |
Which of these are the monosaccharides that combine to make maltose?A. Glucose+FructoseB. Glucose+GalactoseC. Glucose+Glucose |
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A |
Which of the ff is the link of sucrose and its sources? A. a 1-2; green plants B. a 1-4; milk of mammals C. a 1-4; breakdown of starches |
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B |
Which of the ff is the link of lactose and its sources?A. a 1-2; green plantsB. a 1-4; milk of mammalsC. a 1-4; breakdown of starches |
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C |
Which of the ff is the link of maltose and its sources?A. a 1-2; green plantsB. a 1-4; milk of mammalsC. a 1-4; breakdown of starches |
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Saccharum officinarum; graminae, Beta vulgaris; Chenopodiaceae, Acer saccharum; Aceraceae |
Sources of sucrose (give scientific name; family) |
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C |
Uses of sucrose, except: A. Pharmaceutical necessity B. Demulcent C. Vitamin D. Nutrient E. Bacteriostatic F. Preservatives G. Masks disagreeable tastes in troches and tablets H. Retards oxidation in certain preparations |
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Bos taurus; Bovidae |
Sources of Lactose(give scientific name; family) |
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Malted milk |
It is prepared by evaporating milk, an extract of malt. |
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Odorless, Faintly sweet |
Lactose has an ______, _________ taste. |
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D |
Uses of Lactose, except: A. Nutrient B. Pharmaceutic necessity C. Tablet diluent D. Emollient |
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Lactase |
Lactose is hydrolyzed by the specific enzyme called _______. |
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Maltose |
Aka maltobiose or malt sugar, this disaccharide is produced when amylase breaks down starch. |
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False |
Maltose is found in nongerminating seeds such as barley as they breakdown their starch stores to use for food. True or False? |
Germinating |
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Maltose |
This disaccharide can also be produced when glucose is caramelized and can be obtained by hydrolysis of glycogen or starch. |
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Oligosaccharides |
It is a carbohydrate polymer comprised of 3-10 monosaccharides or simple sugars. |
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O-glycosidic bond, N-glycosidic link |
Oligosaccharides are linked together by: |
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Galactooligosaccharides |
These are synthesized through enzymatic connection of lactose. |
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Human milk oligosaccharides |
They are complex glycans that can be found in breastmilk. The backbone of this is the disaccharide lactose which is formedby the linkage between galactose and glucose sugars. |
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Chicory root Jerusalem artichokes Onions Legumes Wheat Asparagus Jicama |
Plants with large amount of oligosaccharides (7) |
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Polysaccharides |
These are polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic bond and on hydrolysis give the constituent monosaccharides or oligosaccharides. |
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Linear to highly branched |
Polysaccharides range in structure from ___________. |
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Homopolysaccharide, Heteropolysaccharide |
Starch may be classified as: |
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Homopolysaccharide |
Contains only a single type of monosaccharide; may be branched or unbranched. |
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Heteropolysaccharide |
Contains 2 or more monosaccharides; may be branched or unbranched. |
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False |
Starch serves as the permanent storage form of photosynthetic products. True or false? |
Temporary storage form |
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Starch |
It serves as the permanent reserve food material for the plants and the chief storage form of carbohydrates in plants. |
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B |
Uses of starch, except: A. Ingredient in dusting powders B. Buffering agent C. Pharmaceutic aid D. Paper sizing E. Cloth sizing F. Laundry starching G. Starting material from which liquid glucose, dextrose,bhigh fructose sweeteners are made |
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Inulin |
It is obtained from the subterranean organs of the members of the Compositae family (Taraxacum, inula, lappa, echinacea & chicory). |
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True |
Inulin is used in culture media as fermentative identifying agent for certain bacteria and for the evaluation of renal function. True or False? |
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Dextran |
It is a water soluble polysaccharide of glucose produced by the action of transglucosylase enzyme system present in Leuconostoc mesenteroides. |
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True |
Dextran is used as plasma expanders in cases of shocj caused by hemorrhage and employed to reduce blood viscosity and to improve microcirculation at low flow states. True or False? |
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Cellulose |
A rigid, colorless, unbranched, insoluble, long chain polysaccharide, consisting of 3000 to 5000 glucose residues and forming the structure of most plant and of plant cells. |
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Gums |
These are natural plant hydrocolloids that that may be classified as anionic or non-ionic polysaccharide or salts of polydaccharides |
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C |
Uses of gums, except: A. Ingredients in dental and other adhesives and in bulk laxatives B. Pharmaceutic aid C. Nutrient D. Tablet binders, emulsifiers, gelating agents, suspending agents, stabilizers and thickeners |
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Glycogen |
Storage form of carbohydrates in animals and fungi; multibranched polysaccharide of glucose. |
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True |
Glycogen is a multibranched polysaccharide of glucose. True or false? |
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Astragalus gummifer |
Scientific name of the origin of tragacanth. |
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AB |
Coming from the legumunosae family, tragacanth consists of what act. ingredient? A. Bassorin B. Tragacanthin C. Astragalusin D. NOTA |
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Acacia senegal |
Scientific name of the origin of Acacia. |
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AB |
Coming from the leguminosae family, acacia consists of what act. ingredient? A. Arabin B. Enzymes C. Bassorin |
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F |
Uses of tragacanth, except: A. Suspening agent B. Emulsifying agent C. Adhesive D. Demulcent E. Emollient F. Binder |
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G |
Uses of acacia, except: A. Suspening agent B. Emulsifying agent C. Adhesive D. Demulcent E. Emollient F. Binder G. NOTA |
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