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86 Cards in this Set

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True

Pharmacognosy literally means the knowledge of drugs or pharmaceuticals. True or False?

Pharmacognosy

It is also defined as an applied science that deals with the biologic, biochemical and economic features of natural drugs and their constituents originated from plants and animals.

Crude

Pharmacognosy is the study of ______ drugs.

Dioscorides

•Greek Physician


•Wrote De Materia Medica in 78 A.D.

De Materia Medica

This consists of about 600 plants described by Dioscorides that were known to have medicinal properties.

78 A.D.

Galen

Greek Pharmacist-Physician


•Lived in Rome


•Described the method of preparing formulas known to have medicinal properties

False

Crude drugs are fruits or animal drugs that consists of natural substances that have not undergone only the process of collection and drying. True or False?

Vegetables; that have undergone

Crude Drugs

These are any products that have not been advanced in value or improved in condition by shedding, grinding, chipping, crushing, distilling, evaporating, extracting, artificial mixing with other substances.

Natural Substances

These are found in nature that comprise the whole plants and herbs and anatomic parts thereof.

C

These are examples of natural substances, except:


A. Sap


B. Extracts


C. Bark


D. Secretions


E. Whole Animals


F. Animal Organs

ABCEF

Process of preparing drugs for commercial market:


A. Collection


B. Harvesting


C. Drying


D. Extracting


E. Garbling


F. Packaging, storage, preservation

ABCDFG

Effects of moisture associated with improper storage and preservation: (Choose all that apply)


A. ⬆ weight of drug


B. ⬇ percentage of act. const.


C. Favors enzymatic activity


D. Facilitates fungal growth


E. ⬆percantage of act. const.


F. Highly colored drugs


G. Undesirable changes in const.

True

Effects of air associated with improper storage and preservation increases oxidation of the const. of the drugs. True or False?

65 C

For the protection of frugs against attacks by insects, expose the drug to a temperature of ______.

Methyl bromide

For the fumigation of large lots of drugs, use ______.

Tight, light-resistant containers

For small lots of drugs, store in :

Organoleptic, microscopic, biologic, chemical, physical

Different methods of evaluating drugs (5)

Morphologic, Taxonomic, Therapeutic/Pharmacologic, Chemical

Classification of drugs (4)

Inert/inactive constituents

They have no definitive pharmacologic activity.


Their presence sometimes prevent the absorbability or potency of the active constituents.

Active Constituents

They are responsible for the therapeutic effect.

Pharmaceutically active

These are constituents that may cause precipitation or other chemical changes in a medicinal preparation.

Pharmacologically active

These are constituents that are responsible for the therapeutic activity of the drug, it's eaither single chemical substances or mixtures of principle.

C

The ff statements about Carbohydrates are true, except:


A. It is the major source of energy


B. It is the most abundant biomolecule on earth


C. It is the secondary source of energy for all living organism


D. Serves as structural components


E. They are aldehydes or ketones containing CHO


F. First products formed in photosynthesis

It is the MAIN source of energy

Sugars, polysaccharides

Classification of carbohydrates (2)

Monosaccharides

These are compounds that cannot be hydrolyzed to simple sugars.

Disaccharides

Yields two monosaccharide molecules on hydrolysis.

Trisaccharides

Yields three monosaccharide molecules on hydrolysis.

Tetrasaccharides

Yields four monosaccharide molecules on hydrolysis.

Monosaccharide

•simple sugars


•smallest unit that make up carbohydrates


•building blocks

Glucose, Galactose, Fructose

Three main monosaccharides in the human diet.

C

Other names of glucose, except:


A. D-glucose


B. Blood sugar


C. Milk sugar


D. Dextrose


E. Corn sugar


F. Grape sugar

False

Glucose appears in the urine in gestational diabetes. True or false?

Appears in Diabetes mellitus

Glucose

It is an aldohexose obtained by controlled enzymatic hydrolysis of starch.

True

Aka milk sugar, galactose is less sweet than glucose. True or false?

Galactose

It is synthesized in the body where it is formed associated with glycolipids and glycoproteins. It is also a component of lactose and other oligosaccharides, cerebrosides and gangliosides, glycolipids and glycoproteins.

A

Other names of Fructose, except:


A. Blood sugar


B. Fruit sugar


C. Levulose


D. Hexulose


E. D-fructose


F. D-arabino


G. D-fructofuranose

Fructose

•It is absorbed directly into the bloodstream during digestion


most water-soluble of all the sugars

Disaccharides

It is a carbohydrate which is formed when 2 simple sugars undergo condensation rxn which involves the elimination of a small molecule such as water from the functional group.

Sucrose, Lactose, Maltose

Most common disaccharides (3)

A

Other name of sucrose:


A. Table Sugar


B. Milk Sugar


C. Malt sugar

B

Other name of lactose:A. Table SugarB. Milk SugarC. Malt sugar

C

Other name of maltose:A. Table SugarB. Milk SugarC. Malt sugar

A

Which of these are the monosaccharides that combine to make sucrose?


A. Glucose+Fructose


B. Glucose+Galactose


C. Glucose+Glucose

B

Which of these are the monosaccharides that combine to make lactose?A. Glucose+FructoseB. Glucose+GalactoseC. Glucose+Glucose

C

Which of these are the monosaccharides that combine to make maltose?A. Glucose+FructoseB. Glucose+GalactoseC. Glucose+Glucose

A

Which of the ff is the link of sucrose and its sources?


A. a 1-2; green plants


B. a 1-4; milk of mammals


C. a 1-4; breakdown of starches

B

Which of the ff is the link of lactose and its sources?A. a 1-2; green plantsB. a 1-4; milk of mammalsC. a 1-4; breakdown of starches

C

Which of the ff is the link of maltose and its sources?A. a 1-2; green plantsB. a 1-4; milk of mammalsC. a 1-4; breakdown of starches

Saccharum officinarum; graminae, Beta vulgaris; Chenopodiaceae, Acer saccharum; Aceraceae

Sources of sucrose


(give scientific name; family)

C

Uses of sucrose, except:


A. Pharmaceutical necessity


B. Demulcent


C. Vitamin


D. Nutrient


E. Bacteriostatic


F. Preservatives


G. Masks disagreeable tastes in troches and tablets


H. Retards oxidation in certain preparations

Bos taurus; Bovidae

Sources of Lactose(give scientific name; family)

Malted milk

It is prepared by evaporating milk, an extract of malt.

Odorless, Faintly sweet

Lactose has an ______, _________ taste.

D

Uses of Lactose, except:


A. Nutrient


B. Pharmaceutic necessity


C. Tablet diluent


D. Emollient

Lactase

Lactose is hydrolyzed by the specific enzyme called _______.

Maltose

Aka maltobiose or malt sugar, this disaccharide is produced when amylase breaks down starch.

False

Maltose is found in nongerminating seeds such as barley as they breakdown their starch stores to use for food. True or False?

Germinating

Maltose

This disaccharide can also be produced when glucose is caramelized and can be obtained by hydrolysis of glycogen or starch.

Oligosaccharides

It is a carbohydrate polymer comprised of 3-10 monosaccharides or simple sugars.

O-glycosidic bond, N-glycosidic link

Oligosaccharides are linked together by:

Galactooligosaccharides

These are synthesized through enzymatic connection of lactose.

Human milk oligosaccharides

They are complex glycans that can be found in breastmilk. The backbone of this is the disaccharide lactose which is formedby the linkage between galactose and glucose sugars.

Chicory root


Jerusalem artichokes


Onions


Legumes


Wheat


Asparagus


Jicama

Plants with large amount of oligosaccharides (7)

Polysaccharides

These are polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic bond and on hydrolysis give the constituent monosaccharides or oligosaccharides.

Linear to highly branched

Polysaccharides range in structure from ___________.

Homopolysaccharide, Heteropolysaccharide

Starch may be classified as:

Homopolysaccharide

Contains only a single type of monosaccharide; may be branched or unbranched.

Heteropolysaccharide

Contains 2 or more monosaccharides; may be branched or unbranched.

False

Starch serves as the permanent storage form of photosynthetic products. True or false?

Temporary storage form

Starch

It serves as the permanent reserve food material for the plants and the chief storage form of carbohydrates in plants.

B

Uses of starch, except:


A. Ingredient in dusting powders


B. Buffering agent


C. Pharmaceutic aid


D. Paper sizing


E. Cloth sizing


F. Laundry starching


G. Starting material from which liquid glucose, dextrose,bhigh fructose sweeteners are made

Inulin

It is obtained from the subterranean organs of the members of the Compositae family (Taraxacum, inula, lappa, echinacea & chicory).

True

Inulin is used in culture media as fermentative identifying agent for certain bacteria and for the evaluation of renal function. True or False?

Dextran

It is a water soluble polysaccharide of glucose produced by the action of transglucosylase enzyme system present in Leuconostoc mesenteroides.

True

Dextran is used as plasma expanders in cases of shocj caused by hemorrhage and employed to reduce blood viscosity and to improve microcirculation at low flow states. True or False?

Cellulose

A rigid, colorless, unbranched, insoluble, long chain polysaccharide, consisting of 3000 to 5000 glucose residues and forming the structure of most plant and of plant cells.

Gums

These are natural plant hydrocolloids that that may be classified as anionic or non-ionic polysaccharide or salts of polydaccharides

C

Uses of gums, except:


A. Ingredients in dental and other adhesives and in bulk laxatives


B. Pharmaceutic aid


C. Nutrient


D. Tablet binders, emulsifiers, gelating agents, suspending agents, stabilizers and thickeners

Glycogen

Storage form of carbohydrates in animals and fungi; multibranched polysaccharide of glucose.

True

Glycogen is a multibranched polysaccharide of glucose. True or false?

Astragalus gummifer

Scientific name of the origin of tragacanth.

AB

Coming from the legumunosae family, tragacanth consists of what act. ingredient?


A. Bassorin


B. Tragacanthin


C. Astragalusin


D. NOTA

Acacia senegal

Scientific name of the origin of Acacia.

AB

Coming from the leguminosae family, acacia consists of what act. ingredient?


A. Arabin


B. Enzymes


C. Bassorin

F

Uses of tragacanth, except:


A. Suspening agent


B. Emulsifying agent


C. Adhesive


D. Demulcent


E. Emollient


F. Binder

G

Uses of acacia, except:


A. Suspening agent


B. Emulsifying agent


C. Adhesive


D. Demulcent


E. Emollient


F. Binder


G. NOTA