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67 Cards in this Set

  • Front
  • Back

The human nervous system is compromised of?

Neurons and Glia

The human brain contains approx. ___ _______ individual neurons.

100 Billion

The cerebral cortex and associated area contains about _______ neurons.

12 to 15 billion

The cerebellum contains about _______ neurons.

70 billion

The spinal cord contains about ______ neurons.

1 billion

- In the late 1800's, what did Spaniard Santiago Ramon y Cajal demonstrate?


- What did he show?

- First to demonstrate that the individual cells compromising the nervous system remained separate.


- Showed that they did not grow into each-other as previously believed.

What do neurons contain?

Membrane, Nucleus, Mitochondria, Ribosomes, Endoplasmic reticulum

What are the parts of a cell?

Cell membrane, Nucleus, Mitochondria, Ribosomes, Endoplasmic reticulum.

What does the cell membrane do?

separates the inside of the cell from the outside environment.

What does the nucleus do?

contains the chromosomes

What does the mitochondria do?

structure that performs metabolic activities and provides energy for the cells.

Define ribosomes

sites at which the cell synthesizes new protein molecules.

Define Endoplasmic reticulum

network of thin tubes that transport newly synthesized proteins to their location

What are the three types of Neurons that we will discuss?

Motor Neurons, Sensory Neurons, and Intrinsic Neurons

Define Motor Neurons

- Take information from the brain and send it to the muscles.


- Receive information from the brain, run through the spinal cord, and have a long axons that extend to, and synapse with, a muscle.

Define Sensory Neurons

- Take information from our senses and send it to the brain.


- Are connected to our sense organs and extend to our spinal cord, and then to the brain.

Which parts of the sensory neurons don't go through the spinal cord?

our ears and eyes, because they are so close to our brain.

Define Intrinsic Neurons

- Neurons that are entirely in the spinal cord or brain.


- Often, once a sensory or motor neuron reaches the spinal cord, it synapses with an intrinsic Neuron which passes the information along by synapsing with other motor or sensory neurons.

What are all of the major components of neurons?

Dendrites, Soma/Cell Body, Axon, Presynaptic terminals (axon terminals)

Define Dendrites

Are branching fibers with a surface lined with synaptic receptors responsible for bringing information into the neuron.

What do some dendrites also contain?

Also contain dendrite spines.

What do Dendrite spines do?

They further branch out and increase the surface area of the dendrite.

The greater the surface area of the dendrite, the more __________ __ ____ ________.

information it can receive.

What does the cell body/soma contain?

contains the nucleus, mitochondria, ribosomes, and other cell structures.

Define Axon

Thin fiber of a neuron responsible for transmitting nerve impulses toward other neurons, organs or muscles.

Define myelin

Insulating materials that cover some neurons

Define Presynaptic terminals

the end points of an axon where chemicals are released to communicate with other neurons

What are the two terms that describe the neuron.

Afferent axon and efferent axon

Define Afferent Axon

Bringing information into a structure

Define Efferent Axon

Carrying information away from a structure

What does the shape of a neuron determine?

It's connection with other neurons and contribution to the nervous system.

What is the Glia?

The other major components of the nervous system

What are some of the functions of Glia?

- Help synchronize the activity of the axon by wrapping around the presynaptic terminal and taking up chemicals released by the axon.


- Remove waste material and other microorganisms that could prove harmful to the neuron.


- Build the myelin sheath that surrounds and insulates certain vertebrate axons.


- Guide the migration of neurons and the growth of their axons and dendrites during embryonic development.

Define the Blood-Brain Barrier

- Is a mechanism that surrounds the brain and blocks most chemicals from entering it


- Made of cells that are very tightly packed together

What does the blood brain barrier block?

Incoming viruses, bacteria, or other harmful material from getting into the brain.

What molecules pass freely through the Barrier?

Oxygen and carbon Dioxide

What particles need help to pass through the barrier?

Glucose and amino acids

Define Active Transport

is the protein-mediated process that expends energy to pump certain chemicals from the bloodstream into the brain.

What uses active transport to get to the brain?

Glucose, certain hormones, amino acids, and a few vitamins.

What are all results from BBB Breakdown?

Meningitis, Multiple Sclerosis, and perhaps Alzheimer's Disease

What do neurons rely on for energy?

Glucose

What do neurons also need a steady supply of?

Oxygen, 20% of all oxygen consumed by the body is used by the brain

What does the body need to use glucose?

Thiamine (Vitamin A)

At rest, what does a neuron maintain?

It maintains an electrical polarization or a difference in the electrical charge of the two locations

Define resting potential

the state of the neuron prior to the sending of a nerve impulse

Define selectively permeable

Allowing some chemicals to pass more freely than others

What passes through channels in the membrane?

Sodium, Potassium, Calcium, and chloride

Define the sodium-potassium pump

Is a protein complex that continually pumps 3 sodium ions out of the cells while drawing 2 potassium ions into the cell which maintains the negative charge

Define the electrical gradient

The difference in charge between the inside and outside of the cell

Define the concentration gradient

Means the cell tries to maintain a balance of potassium and sodium inside and outside the cell

What pulls potassium ions into the cell?

Electrical gradient

Define action potential

is a rapid depolarization of the neuron

define threshold of excitation

A level above which any stimulation produces an action potential

The resting potential remains stable until the neuron is _________.

stimulated

Define Hyperpolarization

Increasing the polarization or the difference between the electrical charge of two places

Define Depolarization

Decreasing the polarization towards zero

In an action potential what happens to Sodium ions and its channels?

Sodium channels are opened, positively charged sodium ions rush in and a subsequent nerve impulse occurs.

After an action potential occurs, what happens to the sodium channels?

Quickly close

Why do potassium ions flow out?

Due to the concentration gradient

What do local anesthetic drugs do?

They block sodium channels and therefore prevent action potentials rom occuring

Define the all-or-none law

States that the amplitude and velocity of an action potential are independent of the intensity of the stimulus that initiated it.

After an action potential what period does a neuron enter?

Refractory Period

Define the refractory period

The neuron resists the production of another action potential

Define the absolute refractory period

is the first part of the period in which the membrane cannot produce an action potential

Define the relative refractory period

is the second part of the period which it takes a stronger than usual stimulus to trigger an action potential

What are the myelin sheath of axons interrupted by?

Nodes of Ranvier

What happens at each node of Ranvier?

the action potential is regenerated by a chain of positively charged ion pushed along by the pervious segment.