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67 Cards in this Set
- Front
- Back
The human nervous system is compromised of? |
Neurons and Glia |
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The human brain contains approx. ___ _______ individual neurons. |
100 Billion |
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The cerebral cortex and associated area contains about _______ neurons. |
12 to 15 billion |
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The cerebellum contains about _______ neurons. |
70 billion |
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The spinal cord contains about ______ neurons. |
1 billion |
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- In the late 1800's, what did Spaniard Santiago Ramon y Cajal demonstrate? - What did he show? |
- First to demonstrate that the individual cells compromising the nervous system remained separate. - Showed that they did not grow into each-other as previously believed. |
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What do neurons contain? |
Membrane, Nucleus, Mitochondria, Ribosomes, Endoplasmic reticulum |
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What are the parts of a cell? |
Cell membrane, Nucleus, Mitochondria, Ribosomes, Endoplasmic reticulum. |
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What does the cell membrane do? |
separates the inside of the cell from the outside environment. |
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What does the nucleus do? |
contains the chromosomes |
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What does the mitochondria do? |
structure that performs metabolic activities and provides energy for the cells. |
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Define ribosomes |
sites at which the cell synthesizes new protein molecules. |
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Define Endoplasmic reticulum |
network of thin tubes that transport newly synthesized proteins to their location |
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What are the three types of Neurons that we will discuss? |
Motor Neurons, Sensory Neurons, and Intrinsic Neurons |
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Define Motor Neurons |
- Take information from the brain and send it to the muscles. - Receive information from the brain, run through the spinal cord, and have a long axons that extend to, and synapse with, a muscle. |
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Define Sensory Neurons |
- Take information from our senses and send it to the brain. - Are connected to our sense organs and extend to our spinal cord, and then to the brain. |
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Which parts of the sensory neurons don't go through the spinal cord? |
our ears and eyes, because they are so close to our brain. |
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Define Intrinsic Neurons |
- Neurons that are entirely in the spinal cord or brain. - Often, once a sensory or motor neuron reaches the spinal cord, it synapses with an intrinsic Neuron which passes the information along by synapsing with other motor or sensory neurons. |
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What are all of the major components of neurons? |
Dendrites, Soma/Cell Body, Axon, Presynaptic terminals (axon terminals) |
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Define Dendrites |
Are branching fibers with a surface lined with synaptic receptors responsible for bringing information into the neuron. |
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What do some dendrites also contain? |
Also contain dendrite spines. |
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What do Dendrite spines do? |
They further branch out and increase the surface area of the dendrite. |
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The greater the surface area of the dendrite, the more __________ __ ____ ________. |
information it can receive. |
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What does the cell body/soma contain? |
contains the nucleus, mitochondria, ribosomes, and other cell structures. |
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Define Axon |
Thin fiber of a neuron responsible for transmitting nerve impulses toward other neurons, organs or muscles. |
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Define myelin |
Insulating materials that cover some neurons |
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Define Presynaptic terminals |
the end points of an axon where chemicals are released to communicate with other neurons |
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What are the two terms that describe the neuron. |
Afferent axon and efferent axon |
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Define Afferent Axon |
Bringing information into a structure |
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Define Efferent Axon |
Carrying information away from a structure |
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What does the shape of a neuron determine? |
It's connection with other neurons and contribution to the nervous system. |
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What is the Glia? |
The other major components of the nervous system |
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What are some of the functions of Glia? |
- Help synchronize the activity of the axon by wrapping around the presynaptic terminal and taking up chemicals released by the axon. - Remove waste material and other microorganisms that could prove harmful to the neuron. - Build the myelin sheath that surrounds and insulates certain vertebrate axons. - Guide the migration of neurons and the growth of their axons and dendrites during embryonic development. |
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Define the Blood-Brain Barrier |
- Is a mechanism that surrounds the brain and blocks most chemicals from entering it - Made of cells that are very tightly packed together |
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What does the blood brain barrier block? |
Incoming viruses, bacteria, or other harmful material from getting into the brain. |
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What molecules pass freely through the Barrier? |
Oxygen and carbon Dioxide |
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What particles need help to pass through the barrier? |
Glucose and amino acids |
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Define Active Transport |
is the protein-mediated process that expends energy to pump certain chemicals from the bloodstream into the brain. |
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What uses active transport to get to the brain? |
Glucose, certain hormones, amino acids, and a few vitamins. |
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What are all results from BBB Breakdown? |
Meningitis, Multiple Sclerosis, and perhaps Alzheimer's Disease |
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What do neurons rely on for energy? |
Glucose |
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What do neurons also need a steady supply of? |
Oxygen, 20% of all oxygen consumed by the body is used by the brain |
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What does the body need to use glucose? |
Thiamine (Vitamin A) |
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At rest, what does a neuron maintain? |
It maintains an electrical polarization or a difference in the electrical charge of the two locations |
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Define resting potential |
the state of the neuron prior to the sending of a nerve impulse |
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Define selectively permeable |
Allowing some chemicals to pass more freely than others |
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What passes through channels in the membrane? |
Sodium, Potassium, Calcium, and chloride |
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Define the sodium-potassium pump |
Is a protein complex that continually pumps 3 sodium ions out of the cells while drawing 2 potassium ions into the cell which maintains the negative charge |
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Define the electrical gradient |
The difference in charge between the inside and outside of the cell |
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Define the concentration gradient |
Means the cell tries to maintain a balance of potassium and sodium inside and outside the cell |
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What pulls potassium ions into the cell? |
Electrical gradient |
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Define action potential |
is a rapid depolarization of the neuron |
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define threshold of excitation |
A level above which any stimulation produces an action potential |
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The resting potential remains stable until the neuron is _________. |
stimulated |
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Define Hyperpolarization |
Increasing the polarization or the difference between the electrical charge of two places |
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Define Depolarization |
Decreasing the polarization towards zero |
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In an action potential what happens to Sodium ions and its channels? |
Sodium channels are opened, positively charged sodium ions rush in and a subsequent nerve impulse occurs. |
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After an action potential occurs, what happens to the sodium channels? |
Quickly close |
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Why do potassium ions flow out? |
Due to the concentration gradient |
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What do local anesthetic drugs do? |
They block sodium channels and therefore prevent action potentials rom occuring |
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Define the all-or-none law |
States that the amplitude and velocity of an action potential are independent of the intensity of the stimulus that initiated it. |
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After an action potential what period does a neuron enter? |
Refractory Period |
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Define the refractory period |
The neuron resists the production of another action potential |
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Define the absolute refractory period |
is the first part of the period in which the membrane cannot produce an action potential |
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Define the relative refractory period |
is the second part of the period which it takes a stronger than usual stimulus to trigger an action potential |
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What are the myelin sheath of axons interrupted by? |
Nodes of Ranvier |
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What happens at each node of Ranvier? |
the action potential is regenerated by a chain of positively charged ion pushed along by the pervious segment. |