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30 Cards in this Set

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  • Back
Define Virchow's triad.
= three major factors for thrombus formation

1. turbulent blood flow (ie bifurcations, aneurysms, venous stasis)
2. vessel wall damage
3. excess clotting
Differentiate these terms:
thrombocythemia, thromboembolus, embolus
thrombocythemia = excess platelets
thromboembolus (aka embolus) = when part of thrombus breaks off and travels
Vessel obstruction leads to ?
infact (tissue necrosis via insuffeicient arterial blood supply)

the process of an infarct = infarction
What happens when a thromboembolus occludes
- a vein?
- an artery?
- a heart vessel?
- a brain vessel?
vein -> usually pulmonary embolism
artery --> usually from heart to brain/intestines/lower extremities/ kidneys
heart --> MI
brain --> stroke
WHat is coarctation?
narrowing of a vessels

usually used to describe a congenital heart defect. (ie coarctation of the aiorta)
stenosis vs coarctation
stenosis = narrowing of valve
coarctation = narrowing of (great) vessels
What does a difribillator do?
it provides an electric shock to a heart with a conduction problem, in which the heart quivers instead of beating (fibrillation)

it is much like a slap in the face to a hysterical person
When cardiac conduction stops at the AV node, what happens?
ventricles and atria beat at their own rates.

the failure of conduction = heart block
Patient's calf is tender when foot is dorsiflexed. What might this be?
deep vein thrombosis (aka Homan's sign)
What three major body systems are affected by hypertension? How?
CNS - sudden inc in pressure (hypertensive crisis) causes vessel damage, and leakage

Cardiovascular - atherosclerosis, small vessels, heart strain

renal system - nephrosclerosis. snowball effect of aldosterone trying to increase pressure and blood flow to kidneys.
Shock is when blood pressure drops. T of F?
F. Shock is when circulation fails, and there is impaired perfusion to vital organs.

hypotension is a late stage of shock.
What are the different kinds of shock?
cardiogenic shock (MI)
hypovolemic shock
systemic shock
- septic shock
- anaphylactic shock
- neurogenic shock
What causes septic shock? How serious is it?
caused by massive inflammatory response (vasodilation for inc permeability)

very serious. 30-50% mortality rate
What is best position for a person undergoing shock? and why?
supine with legs elevated maximizes cerebral blood flow.
Heart failure is when the heart fails to contract. T or F.
F. Heart failure can result from ineffective contraction (systolic failure) or ineffective relaxation (diastolic failure)
Can valve stenosis cause heart failure?
Yes. increased workloads on heart cmay contribute to heart failure.
Left heart failure aka?
congestive heart failure
What is congestive heart failure
another name for left heart failure. results in pulmonary edema.
What is cor pulmonale?
right heart alteration as a result of a primary disorder of lung (ie hypertension, infection, inflammation, edema)

right heart failure may be caused by lung issues
How does left heart failure cause right heart failure?
left heart failure causes pulmonary edema, which causes right heart failure
how does the body compensate during heart failure?
ease congestion and improve cardiac pumping to continue oxygenation of tissues

1. improve venous return (which improves CO)
2. stimulate sympathetic nervous system (inc heart rate and vessel tone)
3. stimulate renen-angiotenisn
4. enlarge heart muscle - helps cardiac contractility
What is DIC?
disseminated intravascular coagulation

- widespread thrombi formation depletes clotting factors, allowing massive hemorrhage
This is the most common site for atherosclerosis.
bifurcation of the common carotid.
What is preload and afterload?
preload is the pressure that stretches the ventricles before ventricular systole
(end volumetric pressure)

afterload is the "load" (or pressure) that the ventricles must pump against
How can you calculate blood pressure?
BP = CO x R (periph resistance)
What is a myocardial infarction?
infaction = tissue necrosis due to ischemia
What are the kinds of MI's?
transmural infarct = full thickness infarct (endocardium to epicardium)

subendocardial infarct = partial wall necrosis
What causes an MI?
- blockage of coronary artery
- arterial spasm
- sudden increased mycardial O2 requirements (vigorous activities)
Cardiac arrest is? results from?
= heart stops pumping

- myocardial ischemia --> arrhythmia/ ventricular fibrillation
- Asystole - complete cessation of contractions
MI vs Cardiac arrest
MI = cardiac tissue necrosis due to ischemia

Cardiac arrest = electrical conduction dysfunction, resulting in cessation of contractions