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13 Cards in this Set
- Front
- Back
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What is the action of direct thrombin inhibitors |
They stop the coagulation cascade by binding to thrombin that will form w fibrin and any other free thrombin that's in the blood |
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What are direct thrombin inhibitors used for |
deep vein thrombosis (DVTS) pulmonary embolism (PE) clotting from a fibb |
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Expected side effects of direct thrombin inhibitors |
Bleeding of the gums, bruising, bleeding |
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Adverse effects of direct thrombin inhibitors |
excessive bleeding, thrombocytopenia |
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How do you know when direct thrombin inhibitors are building up toxicity |
blood oozing excessive bleeding, epistaxis, |
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Name the drugs that increases the activity/concentration of direct thrombin inhibitors |
azithromycin, diltiazem, atorvastatin, carvedilol, clarithromycin, cyclosporin, and St John's worth |
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What is the reversal agent direct thrombin inhibitors |
idarocizumab |
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how are direct thrombin inhibitors stored |
in the original bottle and away from moisture or light |
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What allergy reaction can obtain from taking direct thrombin inhibitors |
Wheezing Shortness of Breath rash itching chest tightedness |
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What is the drug ending for direct thrombin inhibitors |
xaban |
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Name the drugs that decrease the effect of direct thrombin inhibitors |
Antacids, Phenytoin, Phenobarbital, Carbamazepine, Dexamethozone |
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If you miss a dose of the drug, when should you take the scheduled drug |
As soon as possible on the same day, but if there is a 6 hour time between you taking and the next one, don't take it |
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Which of the following should you be concerned about and need to educate the patient about DTIs (All that apply) a. "I will take my drugs on time, but if there is 6 hrs before the next, I will not take the missed doze" b."I will store my drugs in my pill container" c. "I will chew or break the capsule before swallowing." d. "I will avoid aspirin and NSAIDs." e. "I'll take the drug with my applesauce." |
B, C, E |
