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7 Cards in this Set

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Gottesman, 1991

Family study Outline

Is SZ more common among closer relatives?

Yes, more common among biological relatives of SZ person.

Children with 2 SZ parents = 46% concordance

Children with 1 SZ parent = 13% conconrdance

children with 1 sibling = 9% concordance

Joseph, 2004

Twin Study Outline

Review of all twin studies prior to 2001

concordance rate for MZ twins = 40.4%

concordance rate for DZ twins = 7.4%

Tienari et al, 2000

Adoption study outline

Rate of SZ development among adoptees of SZ parents.

164 SZ mothers --> 6.7% children got SZ

197 control group --> 2% children got SZ

Joseph, 2004 argument

Twin study Evaluation -

MZ twins are treated more similarly

They share more experiences+identity confusion

Therefore, concordance rate reflects environmental factors

Joseph, 2004 claim

Adoption Study evaluation -

SZ children = selectively placed

Parents informed of condition, therefore more prepared

Haracz, 1982

Dopamine Hypothesis evaluation -

Post-mortem studies review

Antipsychotics b4 death = high dopamine lvls

No antipsychotics = normal dopamine lvls

Therefore, antipsychotics may not be suitable for SZ

Copolov and Crook, 2000

Dopamine Hypothesis Evaluation -

Recent, advanced PET scans show no solid evidence of unusual dopamine lvls in SZ patients

Therefore, undermines Dopemine Hypothesis