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33 Cards in this Set

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  • Back

Percent of body weight for blood?

8%

Amount of blood for males and females?

Males 5-6 L


Females 4-5 L

Temperature of blood?

100.4 F

Hematorcrit % for Males and Females?

Males- 45%-52% Females-37%-48%

RBC count for males and females?

Males- 4.6-6.2 million/uL


Females 4.2-5.4 million/uL

Platelet count?

130,000-360,000/uL

WBC count?

5,000-10,000/uL

Components of blood and percentages?

55% Plasma,


1% Buffycoat: leukocytes and platelets


45% Erythrocytes

Type of connective tissue in blood and 2 components?

Only fluid connective tissue


Hematocrit—packed cell volume


Plasma—fluid portion of blood

Plasma components?

90%Water, also includes; Protein-Enzymes-Nutrients-Waste-Hormones-Gases

Where are plasma proteins made and what are their functions?

most plasma proteins are made in the liver, functions include; defense,clotting & transport

What are three types of plasma proteins?

Albumins, Globulins and Fibrinogen

What are the subcategories of Globulins and what do they do?

Alpha (α)


Prothrombin—blood clotting


Lipoproteins


Beta (β)


Transferrin—iron transport


Complement proteins


Lipoproteins


Gamma (γ)


antibodies(secretedby B-cells)



What is Fibrinogen and what does it do?

Fibrin(sticky protein for blood clotting)

What is nitrogenous waste and name 3 examples?

by products of cellular metabolism including; Urea, creatinine and uric acid

What are the nutrient components of plasma?

Amino acids, glucose (70-110 mg/100mL), fats & cholesterol (↓ 200 mg/100mL), phospholipids, vitamins and minerals

Gas components of plasma?

O2, CO2 and dissolved Nitrogen

Electrolyte component of plasma?

Na+90% (150mEq/L) (important to osmolarity to osmolarity and movement of solutesand water within the body);K+(4mEq/L),Ca+2,Mg+,Cl-,HCO

Hormone component of plasma?

Serum-Plasma W/O clotting proteins

What are the 7 characteristics of Erythocytes?

-Transports CO2 and O2


-Disc shaped for greater surface area


-Plasma membrane has antigens (glycocalyx)


-Life-span of 3-4months


-Devoid of most organelles-no mitochondria (can’t use up the O2)


-Carbonic anhydrase (CAH) CO2 + H2O ↔ H2 CO3 ↔ HCO3- + H+


-Hemoglobin (15g/100mL) carriers O2 (in cytoplasm)



What are 4 characteristics of Erythocyte hemoglobin?

- 4 protein chains


- Heme molecule with iron→ binds O2


- HbA- adult


- HbF- fetal binds O2 more tightly

Type of Leukocyte: What is a Granulocyte?

a white blood cell with secretory granules in its cytoplasm, e.g., an eosinophil or a basophil.

5 Characteristics of Neutrophils?

- 50-70% of WBCs


- 3-5 lobes, cytoplasm stains a pale lilac color with fine granules


- Bacterial infections


- Phagocytosis-release antimicrobial chemicals (lysosomes, defensins)-respiratory burst.


- Sometimes referred to as stab cells-band cells or polymorphonuclear cells (PMN).

3 Characteristics of Eosinophil?

- 2-4%, 2 large lobes-cytoplasm stains a red-orange color with large granules


- Parasitic infections (worms)-allergic reactions


- Phagocytosis-release enzymes to digest the pathogen-destroy antigen-antibody complex and inhibit the effects of inflammation usually associated with allergic reactions.

4 Characteristics of Basophil?

- .5-1%
- Cytoplasmstains a deep bluish-purple color with abundant granules
- Chicken pox-diabetes-polycythemia
- Secrete histamine & heparin → increase blood flow & mobility of WBCs to the infected area.

What are Agranulocyte?

Also known as mononuclear leukocytes, are white blood cells with a one-lobed nucleus. They are characterized by the absence of granules in their cytoplasm, which distinguishes them from granulocytes

What are 2 types of Agranulocytes?

Lymphocytes & Monocytes

3 Characteristics of Lymphocytes?

- 20-30%,


- Spherical nucleus that stains a deep blue-purple


- Diverse infections → destroy cancer cells-activate other immune cells-secrete antibodies

3 types of Lymphocyte antibodies and their characteristics?

- B-cells → become plasma cells → secrete antibodies


- T-cells → attack invading virus-cancer-transplanted tissue


- Killer cells → attack a wide variety foreign substances (non-specific immune response)

4 characteristics of Monocytes?

- 2-8%


- Kidney shaped nucleus that stains blue


- viral infections


- Become macrophages → phagocytosis-activate other cells of immune system (APC)

What is differential WBC count?

Count of each type of WBC → help determine cause of infection-effects of chemotherapy-monitor progress

What is Complete Blood Count

Count of all the formed elements

Function of Platelets?

Form clots and secrete chemicals