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5 Cards in this Set
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A-92. What is the pathology behind proteinurea associated with Minimal Chg Dz, Membranous GNF, and Focal Segmental GNF? (nephrotic)
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Min. Chg Dz: decreased charge selectivity
Mem GNF: decreased size selectivity Focal Seg. GFN: increased permiability due to factors released from lymphocytes |
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A-92. I am analyzing a slide from a patients kidney and there is a "spike-dome" apearence and markedly thickened capillary walls. What dz does this person have?
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Menbranous Glomerularnephritis
Cause: HBV/C, syphilis, malaria, RA drugs |
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A-92. What's the difference between secondary and tertiary hyperparathyroidism associated with renal failure?
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Secondary: RF prevents excretion of phosphorus --> incr serum phos = inc PTH sec
Tertiary: chronic PT stim from above case causes glandular hypertrophy leading to hypersec of PTH --> with secrete PTH w/ correc of calcium phos levels |
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A-92. What is the clinical dyad associated with Renal Artery Stenosis?
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Sudden HTN with decreased K+ --> due to decreased blood flow to the juctoglomerular apparatus
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A-92. What sort of urinary casts would you see in nephrotic syndrome, nephritic syndrome, and chronic dz?
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Nephrotic Syn: fatty casts
Nephritic: RBC casts, granular casts CD: broad waxy casts, pigmented granular casts |
