Nephrotic syndrome is caused by the filtration system becoming more permeable and an increase of proteins being able to cross the epithelial boundary. Nephrotic syndrome is not a disease of the glomerulus, but an issue with the how large proteins are filtered. Due to the loss of the protein plasma, the patient begins to retain fluid and experience edema. The high levels of cholesterol in the blood and urine are thought to occur because the liver produces to compensate for the high albumin production.
Nephritic syndrome occurs when the glomerulus becomes inflamed and the capillary wall is damaged, impairing the filtration of toxins from the blood into the urine. This disorder may occur due to an infection and be a primary disorder or it may be a secondary disorder from a systemic disease. The impaired filtration will manifest as blood in the urine since it was not filtered out. The patient may experience low urine production as well from poor filtration. This may lead to an overload of fluid causing shortness of breath and high blood pressure. The substandard filtration also leads to azotemia, which is abnormal high laboratory values such as BUN, creatinine. …show more content…
The kidneys create and process approximately a liter and a half of urine every day (Port, 2015, p. 599). Inside the kidney, there are more than a million cells that make urine called nephrons. Contained in each nephron is a glomerulus and the job of the glomerulus is to filter the blood. When the glomerulus are attacked the disease that occurs is called glomerulonephritis. The attacks on the glomerulus may come from an infection, the body’s own immune system, a drug, something in the environment, or through a genetic
Nephritic syndrome occurs when the glomerulus becomes inflamed and the capillary wall is damaged, impairing the filtration of toxins from the blood into the urine. This disorder may occur due to an infection and be a primary disorder or it may be a secondary disorder from a systemic disease. The impaired filtration will manifest as blood in the urine since it was not filtered out. The patient may experience low urine production as well from poor filtration. This may lead to an overload of fluid causing shortness of breath and high blood pressure. The substandard filtration also leads to azotemia, which is abnormal high laboratory values such as BUN, creatinine. …show more content…
The kidneys create and process approximately a liter and a half of urine every day (Port, 2015, p. 599). Inside the kidney, there are more than a million cells that make urine called nephrons. Contained in each nephron is a glomerulus and the job of the glomerulus is to filter the blood. When the glomerulus are attacked the disease that occurs is called glomerulonephritis. The attacks on the glomerulus may come from an infection, the body’s own immune system, a drug, something in the environment, or through a genetic