The Use Of Neuropsychologists Used A Functional Magnetic Resonance Imaging ( Fmri ) On Depressed Patients

1395 Words Sep 24th, 2015 6 Pages
Neuropsychologists used a functional magnetic resonance imaging (fMRI) on depressed patients to see how differences in the brain activity when compared to normal people and the result showed that depressed patients have a decreased activity in dorso lateral pre-frontal cortex (DLPFC) but the activity of the amygdala, where is responsible to our emotional reactions such as sadness and happiness, was relatively increased (2007). It would then explain why patients who suffered from depression tend to have an emotional flooding.

The monoamine hypothesis was first introduced during the 1950s and researchers found that the level of serotonin in the brain might be related to the etiology of mood disorders (Hirschfeld, 2000). Over more than three decades, lots of research tried to focus on how the change of the number of monoamine neurotransmitters in our brain might contribute to one of the well-known disorders – depression (Delgado, 2000; ).

The main idea of the monoamine hypothesis is that depression is caused by a deficiency in the levels of monoamine neurotransmitters which are serotonin, norepinephrine and/or dopamine (Delgado, 2000; Hirschfeld, 2000). The idea was supported by the use of antidepressants. Reports, conducted by (Delgado, 2000; 1955,etc) showed that there is an improvement for patients to alleviate their depression symptoms after taking the antidepressants. In order to help patients who suffered from depression, scientists developed many different types of…

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