Amphetamine Drug Discovery

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The process by which new medications are discovered is called drug discovery. Historically, there are some ways to discover drugs, like identifying the active ingredient from traditional remedies or by serendipitous discovery. The drug that my partner and I research for is amphetamine. By definition, amphetamine is a central nervous system stimulant that affects chemicals in the brain. Nowadays, amphetamine is a medicine used to treat attention deficit hyperactivity disorder, narcolepsy, and obesity. The history of amphetamine began in the 1800s, when a Romanian chemist who was named Lazar Edeleanu synthesized the drug from a chemical compound. But it has been unknown until 1927, when Gordon Alles and reported to have sympathomimetic …show more content…
Medically, amphetamine can be used to treat attention deficit hyperactivity disorder, narcolepsy, obesity and depression. For attention deficit hyperactivity disorder, long-term treatment of amphetamine-based medication in children in order to decrease abnormal brain structure and function. However, when ADHD persists into adulthood, amphetamine may be use efficient, because amphetamines are less useful for those individuals who are older. What is more, the side effects of it prompt adults to cease taking it. For narcolepsy, amphetamines have been used to treat it since 1930s, but they have been replaces by modafinil because the side effects of them. For obesity, amphetamines were first used to treat it in the 1930s, too. However, the treatment of it has fallen. So there is a recent small-scale trial using dexamphetamine, in which is a similar molecule to amphetamine. It improved cognitive control and reduction in compulsive behavior, and it attributed to the drug produced significant weight loss. However, the side effects and the potential addiction make medical professionals generally do not recommend use amphetamines to treat obesity. For depression, amphetamines may be used with standard antidepressant medication together to treat …show more content…
Therefore, amphetamines are not widely used and suggested in the medical field. However, there are still some medications available in the U.S. that contains amphetamines, such as Dextroamphetamine, Levoamphetamine, Lisdexamphetamine, Methamphetamine, Adderall, Adderall XR, and Dexedrine. These are amphetamines is inclusive of many of the amphetamines or amphetamine containing drugs that are marketed under various brand names throughout the U.S. amphetamines are legal if they are used by the user who is prescribed the drugs by a legitimate doctor and who knows how to use it correctly. To see it globally, amphetamine was a popular drug of abuse in the U.S. in the 1960s and 1970s, but it then fell from favor. Currently, amphetamines are a far more popular of abuse outside of U.S. In 2008, Europe had more than 80% of all the amphetamine production facilities, and still, far more tonnage of amphetamine was found in

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