The Origin Of The Crispr / Cas9 System Essay

1490 Words May 1st, 2016 null Page
The CRISPR/Cas9 system is a system currently being studied for use as a genetic modification method. It was discovered by scientists working with bacterial cells. It was discovered that bacterial cells utilize a defense system in which they identify viruses that are invading and “chop up” their DNA. This defense mechanism is composed of clustered regularly interspaced short palindromic repeats found within the genome of bacteria. This is the origin of the CRISRP acronym. These CRISPR sequences are specific patterns of DNA sequences that are capable of being edited out of genes. Using the CRISPR system, bacteria are able to destroy the genome of invading viruses and thus prevent the virus from being able to replicate and survive in its host. Scientists began to develop the CRISPR/Cas9 system using this bacterial defense mechanism as a model. This biotechnology has a wide array of possible applications. With ongoing research, CRISPR/Cas9 system could treat many diseases and could be used to avoid certain genetic disorders at birth. It was originally thought that the immune system of bacteria was generic, and would attack anything unfamiliar that invaded it. With research, the CRISPR system in bacteria was discovered. The CRSPR system is considered to be similar to a human immune system. The CRISPR sequences have short sequences in between them called spacers. These spacers are composed of sequences that are composed of the viral DNA that is attacking. In this way, spacers…

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