Type 2 Diabetes And Obesity

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In this article, the author looks at factors like social, genetic, and environmental factors that may impact type 2 diabetes and obesity. When looking at what might cause 10% of the population to have type 2 diabetes and 40% of the population that is overweight the first thing to know is that type 2 diabetes is when the body does not process insulin from the pancreas correctly. Because of the reduction of insulin, there is more lipid deposition in the liver and muscle.
When looking at how diet plays a part in type 2 diabetes, obesity plays a role in developing diabetes 2. Most people who are overweight have diabetes 2 as well as those who have normal weight. Those who are averaged weight that has type 2 diabetes have more issues processing
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There have been studies on rats and microbiome in which the researchers manipulated the microorganisms in the rat’s gut which resulted in weight loss and diabetes release. However, when this study is translated to humans, it is only a little effective. Even if the data of microbiome is limited on humans, it has shown that diet and exercise do anticipate metabolic feedback to food and it tells the individual what they should eat in their diets. Other studies have shown that people’s metabolism effects microbiome in different ways and impacts things like short-chain fatty acid production, bile acid metabolism, and inflammation. However, these studies do not look at how these microorganisms are involved with diabetes 2 and …show more content…
The explanation for this phenomenon is called the fetal programming hypothesis which looks at the effects of maternal diets on the risks of metabolic diseases years later. Studies have found that environmental exposures can affect the fetus’s growth. For example, certain environmental exposures can influence the birth weight of a baby. If the nutrition leads to poor growth and fetal programming than this could result in low birth weight which is connected to diabetes 2. However, children who have high birth weight is not only at an increased risk for type 2 diabetes, but it shows that the mother of the child has high blood sugar. Because the mother has hyperglycemia and the child has a high birth weight, then the child can develop diabetes 2 later in life. Children with high birth weight usually carry diabetes 2 alleles such as MTNR1B and GCK genes while children with a low birth weight will carry diabetes 2 alleles such as ADCY5 and CDKAL1. Because of these findings such as genetics, diet, energy expenditure and early life environment, it gives researchers a better understanding of what may cause diabetes 2 and

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