In a sarcastic tone, Antony repeatedly referred to these "honourable men". Repeating "Honourable men" is also seen to be ironic, he's ridiculing Brutus and the conspirators saying his idea of Caesar being so ambitious, he's a threat, is something to laugh about.
Every time Antony cleverly pauses in his speech to let the plebeians comment, the plebeians are more spiteful toward the conspirators. As the crowd begins to favour Antony the citizens make comments like "Methinks there is much reason in his saying" which shows there change in opinion.
Antony said his speech, after Brutus so Antony could adapt to what Brutus has already said and even prove it wrong. He convinces the crowd that Caesar was great. The crowd would feel guilty about trusting Brutus, after Antony persuaded them he was almost pathetic, this makes the crowd angry and they rebel.
Antony also says "Here was Caesar! When comes such another?" which makes the citizens feel guilty and like they'll never get another Caesar, so they have missed there chance to let Caesar