Reflux Laryngitis Case Study

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Pribuisiene, R., Uloza, V., Kupcinskas, L., & Jonaitis, L. (2006). Perceptual and Acoustic Characteristics of Voice Changes in Reflux Laryngitis Patients. Journal of Voice, 20(1), 128-136.
In 2006, Pribuisiene, Uloza, Kupicinskas, and Jonaitis examined vocal differences in individuals with reflux laryngitis using perceptual, subjective, and instrumental measures. There were 108 participants with reflux laryngitis and 90 individuals in the control group. Acoustic analysis of reflux laryngitis patients included increased amounts of “jitter, shimmer, normalized noise energy, voice handicap index (VHI), and decreased parameters of phonetogram”, while also displaying a decreased length in maximum phonation time” (Pribuisiene, Uloza, Kupicinskas,
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F., Hicks, D. M., Abelson, T. I., & Richter, J. E. (2003, September). Laryngeal Signs and Symptoms and Gastroesophageal Reflux Disease (GERD): A Critical Assessment of Cause and Effect Association. Clinical Gastroenterology and Hepatology, 1(5), 333-344.
Vaezi, Hicks, Abelson, and Richter (2003) sought to investigate the controversy between the diagnosis of gastroesophageal reflux disease (GERD) and laryngeal signs associated with it. One study reviewed that those diagnosed with GERD based solely on laryngeal signs did not respond to natural reflux treatments nor did they have “abnormal esophageal acid exposure” (Vaezi, Hicks, Abelson, Richter, 2003, p. 333). Another study explained the benefit of the expansion of symptomatic characteristics because this has contributed to better sensitivity of diagnosis. In contrast, some professionals in another article believe these increased signs could be a result of other entities such as smoking, alcohol, allergies, asthma, viral illness, or vocal abuse. Those in the study without a diagnosis of reflux occasionally were identified as having laryngeal symptoms accredited to reflux, thus possibly leading to an over identification of GERD. Overall, there are laryngeal signs identified through visualization closely related to symptoms of GERD, however these laryngeal signs can be related to other means as
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Department of Otolaryngology, 1240, 843-851.
Khair and colleagues (2003) sought out to investigate the effects omeprazole has on treating reflux laryngitis, while also examining the difficulties that arise from diagnosing laryngeal complications using signs and symptoms alone as a dependable means of measurement. Fifty-three participants previously diagnosed with reflux laryngitis were involved in the study in which all participants presented with hoarseness, excessive phlegm, throat clearing, throat pain, lump in throat, or chronic cough. Results indicated that the “omeprazole group showed significant improvement in hoarseness and in throat clearing”, while “throat pain decreased significantly with both omeprazole and placebo groups” (Khair et al., 2003, p. 845). Further discussion revealed that that laryngeal signs and symptoms presented within the study could be associated with other diagnoses of laryngeal structures. To conclude, more information is needed on the effectiveness of perceptual and objective measurements with regard to laryngeal signs and symptoms in order to form consistent criteria for future diagnosis of reflux

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