Propionibacterium Acne Case Study

1314 Words 6 Pages

Written by
Ebru Erdogan
Alper Buberci
Helin Alagoz


The purpose of this paper is to explain propionibacterium acne’s structural properties, to make its microbiological analysis, to mention where it can be found, especially on human body, its photosensitivity and to describe the diseases and some infections it can lead to under specific conditions.


Propionibacterium acnes (P. acnes) is a bacteria that grows deep inside of pores, which is relatively slow-growing, typically aerotolerant anaerobic and gram positive type, It feeds on the sebum that is made by the sebaceous glands which surround the base of hair shaft. One of the most prominent properties of these bacterias is that it’s partially
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acnes are members of the “gram-positive” classification of bacteria, that have thick cell walls that are rich in peptidoglycans and lipopolysaccharides (sugar molecules attached to proteins and fatty acids), which includes many other species of infectious bacteria.

It is a common contaminant of cultures and interpretation is difficult when it is isolated from a single specimen. P. acnes is a fastidious organism, when growing on culture it requires at least 6-7 days and the conditions should be also anaerobic. It has been identified at various sites, particularly in the presence of foreign bodies, such as in cases of endocarditis, or bone infection.

The objective of this paper is to go through with following topics on propionibacterium acnes; structural properties and metabolism, photosensitivity, ecology and habitat of the named bacteria, its pathology and the treatments that can be practiced.

Structural Properties and Metabolism

Propionibacteria are slow-growing, non spore forming, gram-positive, anaerobic bacteria. They are generally shaped as bacillus and also they can be rod-shaped or branched and can be observed as singularly, in pairs, or in groups. They generally produce lactic acid, propionic acid, and acetic acid from
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JS614. The entire genome sequence of P. acnes includes 2333 putative genes and reveals numerous gene products involved in degrading host molecules, including sialidases, neuraminidases, endo glycosidases, lipases, and pore-forming factors. [1] One species of Propionibacterium, P. freudenreichii which is used in Swiss cheese manufacturing, is observed to be dependent on free amino acids and peptides made in the cheese by casein degradation of Lactobacillus proteolytic enzymes. It produces carbon dioxide, which is the substance that makes the holes in swiss cheese. The propionic acid produced from breaking down glucose is what gives Swiss cheese its characteristic

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