Pseudomonas Aeruginosa Essay

761 Words 4 Pages
Based on the laboratory tests provided, it can be determined that the unknown organism can be identified as Pseudomonas aeruginosa (P. aeruginosa). This organism is an opportunistic pathogen that can infect non-mammalian, plants, and humans. P. aeruginosa belongs to the bacterial family Pseudomonadaceae, and is a gram-negative rod that approximately measures 0.5 to 0.8 µm by 1.5 to 3.0 µm. It can normally be found in water and soil. Its single polar flagellum makes it motile, and it is known to be one of the fastest swimming bacteria found in hay infusion and pond water (Crittenden, Trussell, Hand, and Howe 2012).
Due the extensive size of the genome, 6.3 million base pairs, P. aeruginosa is capable of adapting to a wide variety of environments
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aeruginosa is a serious threat to immune-compromised patients. It accounts for 35-40% of urinary tract infections in the hospital (Black 2012). In respiratory infections, such as pneumonia it causes hemorrhages and damages the respiratory airways that can be fatal as it causes an inflammatory response (Descamps et al. 2012). This pathogen is known to be the leading cause of respiratory infection in the world (Descamps et al. 2012), which can be ventilator-associated or hospital-acquired pneumonia. In chronic pneumonia, such as in cystic fibrosis, P. aeruginosa is the most frequent cause of mortality (Descamps et al. 2012). The inability to clear trapped bacteria in the mucous promotes microbial colonization and damages the lungs causing poor pulmonary function.
Pseudomonas aeruginosa is also known to be a common causative agent of wound infections. These wound infections are more common in people with weaker immune systems, such as those with diabetes mellitus, as it causes wounds to heal at a slower rate which makes them prone to infections. P. aeruginosa wound infections occur most often in the hospital from surgical wound treatment and are known to be the leading cause of burn infections (Nedeljković, Tiodorović, Kocić, Cirić, Milojković, and Waisi
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Some of the antibiotics for humans include carbapenems (Nedeljković et al. 2015), cephalosporins, and aminoglycosides. Despite the treatment options, this pathogen is highly resistant to the antibiotics. A contributing factor to this resistance is the biofilm the pathogen produces under physiological conditions. The biofilm protects the bacteria from antimicrobial peptides and prolongs the antibiotic treatment. The production of β-lactamases is also an important the mechanisms of resistance (Nedeljković et al. 2015). This highly versatile pathogen is getting more difficult to treat each year and is becoming a crucial problem for public health. Its ability to adapt to various environmental conditions and to acquire new resistance strategies makes it an extremely effective human, plant and non-mammalian

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