Essay on Plasmodium Falciparum

1120 Words Apr 13th, 2015 5 Pages
Plasmodium falciparum is a protozoan parasite. It is unique of the class of Plasmodium that is the foundation and cause malaria in individuals. There are other Plasmodium species that can cause malaria in humans. Nevertheless P. falciparum is the most common, virulent, and deadly. P. falciparum communicable by the female Anopheles mosquito.
P. falciparum life cycle is comprised of two hosts. A P. falciparum carrier female Anopheles mosquito injects sporozoites into the human, infecting their liver cells. Once there infection and damage to red blood cells is critical to the parasites survival. Because red blood cells transport oxygen all over the body, their destruction by P. falciparum causes basic functional devastation to the host.
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Some parasites separate and go into sexual erythrocytic stages. In the blood phase, the parasites form clinical indicators of the disease.
P. falciparum reproductive cycle creates more permeability to the cell, thus allowing a plethora of molecules into the cell, causing the cell to potentially rupture. However once the cell is infected with Plasmodium falciparum the parasite annihilates the inside red blood cell, but full cell remains together for the extent of the parasites' 48 hour reproductive cycle.
A gametocyte male is termed a microgametocytes, and a female is termed a macrogametocytes. They both are acquired during a blood meal by an Anopheles mosquito. The parasites' reproduction and replication cycle in the mosquito is termed the sporogonic cycle.
The microgametes enter the macrogametes producing zygotes in the stomach of the mosquito. The zygotes develop and become ookinetes. They then attack the midgut wall of the mosquito and mature into oocysts. The oocysts lyse and discharge sporozoites, which migrates toward the mosquito's salivary glands. A human is then inoculated with the sporozoites and the malaria life cycle begins.

Details on the major disease(s) caused by this organism. Malaria caused by this species (also called malignant[1] or falciparum[2] malaria) is the most dangerous form of malaria,[3] with the highest rates of complications and mortality. As of 2006, there were an

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