Musculoskeletal conditions have been identified as the third of nine major national health issues ranked by their overall contribution to the burden of disease in Australia 1. Low back pain (LBP) is the most prevalent form of persistent musculoskeletal pain and has an economic burden second only to cancer 2-5. Despite the fact that LBP is a leading cause of suffering and disability 2-4, existing therapies target generic symptoms, achieving limited success, with the Australian National Pain Summit concluding that the ‘management of pain in Australia is shockingly inadequate’ 6. Physical activity, defined as any skeletal muscle contraction resulting in energy expenditure, is thought to be a key factor influencing the development of persistent
