Differences Between Mesalazine And Rifaximin
Mesalamine is a salicylate, its therapeutic effect does not appear to be related to cyclooxygenase inhibition; indeed, traditional non-steroidal …show more content…
2 Chemical Structure of Rifaximin
The review of literature regarding quantitative analysis of Mesalazine and Rifaximin revealed that no Simultaneous Equation method attempt was made to develop analytical methods for Mesalazine and Rifaximin. Some spectrometric methods and chromatographic methods have been reported for the estimation of the individual and combination of drugs.The focus of the present study was to develop and validate a rapid, stable, specific, and economic Spectroscopic method for the estimation of Mesalazine and Rifaximin in Synthetic Mixture.
2. MATERIALS AND METHODS
Chemicals and Reagents
Mesalazine raw material was received as gift sample from CTX Life science, Surat. Rifaximin raw material was received as gift sample from Lupin Ltd, Ankleshwar.
Methanol HPLC Grade (Finar), HPLC Grade Water, Acetonitrile HPLC Grade (Finar), Potassium Dihydrogen Phosphate (Merck), Formic Acid, Ortho Phosphoric Acid AR Grade (Merck), was used for development