Iga Nephropathy Or Berger's Disease

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IgA nephropathy or Berger’s Disease, is a kidney disorder that arises when IgA settles in the kidneys. More specifically, when the IgA protein accumulates or clumps in the small blood vessels of the kidney, triggering inflammation which damages the glomeruli tissue (Mayo Clinic). Your kidneys are two bean-shaped organs located on the posterior abdominal wall. One of the kidneys main functions is to filter toxic waste from the blood; the glomeruli play an important role in this process. The more IgA that damages the glomeruli, the more it forces the kidneys to lose its ability to clear waste.

IgA is an immunoglobulin or antibody developed by the immune system that helps fight infections within our body. It is produced in the mucous, saliva,
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When this disease reaches an advanced stage, dangerous fluid levels can occur, with electrolytes and waste build up in the body. Inhibiting the kidneys from their ability to filter and remove toxins causes complications like high blood pressure and diabetes. Diabetes occurs with extremely high blood sugar levels that can cause many complications in the body. Some complications include; blindness, heart disease and kidney failure.
High blood pressure (hypertension) is due to increased pressure against the walls of capillaries. If not controlled properly this high blood pressure can result in a heart attack, stroke or chronic kidney failure (CKF). Glomerulonephritis (IgA nephropathy), Malformation, Lupus, and urinary infections are all other conditions that affect our kidneys and can build up to chronic kidney disease over time. Many individuals don’t have severe symptoms until the disease advances. Such symptoms include; trouble concentrating, fatigue, loss of appetite, swollen feet and ankles, itchy skin, muscle cramping at night and frequently urinating at night. These symptoms are associated with the Glomerular Filtration Rate (GFR) which is a measurement of your level of kidney function and determines your stage of kidney
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Stage one consists of very mild signs with either a normal or better GFR, and the kidney’s functional capacity is higher than ninety percent. Stage two has mild signs of kidney disease with a reduced GFR, indicating that the kidneys are only functioning sixty to eighty-nine percent. In stage three moderate signs begin to show that chronic renal insufficiency is occurring where the GFR shows the kidneys functioning at forty to fifty-nine percent. Stage four has severe chronic renal insufficiency and the function of the kidneys resides at about fifteen to twenty-nine percent. The last and final stage of Chronic Kidney Disease is stage five, otherwise known as End-Stage Renal Failure. The GFR indicates that the kidneys are functioning under fifteen percent (NKC). Our kidneys are vital organs that contribute to our health and if they function below fifteen percent they are not effectively removing waste and toxins from the

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