The cerebral cortex is a highly folded structure. Therefore, it is hard for visualization as well as computational purposes. The most widely used method to analyze functional brain imaging data is to project the original folded cortical surface onto the surface of a standardized anatomical 3-D space. Most of the procedures are based on Talairach and Tournoux which have significant drawbacks.
Dale and Sereno developed a 3-step procedure to display and analyze functional properties of the cerebral cortex starting with a previously reconstructed cortex. First, the cortical surface will be ‘inflated’ to visualize the activities inside sulci. Second, the hemisphere will be flattened to make it accessible for computational procedures