Central Dogma Of Molecular Biology

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Possible Modifications of Central Dogma of molecular Biology

The central dogma of molecular biology is describes the transfer of genetic information within a biological system and was first stated by Francis Crick in 1956. The central dogma is the flow of genetic information as ‘’DNA makes the RNA and RNA makes the protein.’’All biological cells with few exceptions in some follow this rule. This flow takes place through three fundamental processes: replication, transcription and translation. Central Dogma theory was modified when it was found that in some cases RNA carry the genetic information for DNA. The dogma is basically the transfer of sequenced information between information carrying biopolymers. There are three main classes of such biopolymers: DNA, RNA and protein. This transfer is of three types: general transfers (normally occurs in all cells), special transfers (in viruses), and unknown transfers (never takes place). The general transfers is the normal transfer of biological information catagories in three types: DNA can be copied to DNA (DNA replication), DNA information transcribed into mRNA (transcription), and proteins can be synthesized from mRNA as a template (translation). There are some modifications in central dogma of molecular biology. This review discusses the possible modifications of central dogma of molecular biology.
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each monomer is connected to at most two other monomers). Their sequence encodes information. The sequence of one biopolymer is used as a template for the construction of another biopolymer with a sequence that is totally dependent on the original biopolymer's

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