Chlordane Case Study

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There is not enough evidence to support the correlation between Chlordane, a persistent organic pollutant chemical, and Kidney Cancer. Chlordane was used on U.S. farmland from 1948 to 1988 until it was banned due to the environmental and human harms that were caused by exposure. However, the use of chlordane is only allowed when treating homes for termites up until 1988. Chlordane has been shown to affect the human nervous system, digestive system, and the liver. Chlordane can enter the body through skin if it comes into contact with contaminated soil. It can also enter the body via the lungs if the clean air has been contaminated. Uptake can also occur at a faster rate into the digestive system and skin if chlordane is an oily mixture. There …show more content…
The fatal human dose is expected to be 6g and convulsive symptoms occur with an oral amount of 2.25g. In a human exposure case study by the Department of National Health and Welfare, there were no illness found among workers that were exposed to chlordane from one to three years. Examination of 22 workers showed no signs of symptoms that were found in animals that were exposed in labs. Some observable symptoms that should have been found in the workers that were seen in the exposed rats included but not limited to loss of weight, anorexia, nervous disorder, and disturbance of vision and respiration. However, none of these signs were seen in the workers over a long period of constant exposure. This study just talked about how little harm chlordane can cause when it is exposed to workers that were creating this chemical. This study was determining if the chemical can cause harmful effects in a short period of time and it concludes that little harm was seen in these workers. According to a epidemiology study by Cornell University, there was a study of 45 white children with brain cancer diagnosed between 1985 and 1989. Two groups of controls were …show more content…
The first case study explained the harms that came from workers making this organic chemical. However, in the third case study it shows the dangers of consuming chlordane and what they lethal dose is in humans. This case used mice to experiment with the danger of consuming chlordane. By consuming chlordane there was a high chance of cancer growth in the mice. The abnormal situation is that only 2 major types of cancer were found to be caused by chlordane; liver cancer and brain cancer. But with these case studies there are no real long term research that passed 4 years. Most of these case studies concluded on liver or brain cancer in an immediate exposure. There was a lack of studies on humans with only a large amount of research on animals. There is no correlation between kidney cancer and exposure to chlordane. Because if any human the ingested 6g or more of chlordane orally will have an immediate symptom of convulsion. If a human was exposed to chlordane through air the only symptoms are minor ones that can easily be treated with a long period of rest. However, if chlordane was exposed to the environment there will be a detrimental affect to other living organisms in the environment, which only require a small dose for it to be lethal. Humans need a larger dose for it to become dangerous. Since this chemical has since been banned in the U.S. for

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