There are many guidelines designed to help researchers to organize clinical trials, studies in general, tests and even to help the physicians to plan an experimental treatment strategy. The newest guidelines describe Alzheimer’s as a progressive disease classified into stages: 1) the asymptomatic, preclinical stage (research only), 2) mild cognitive impairment and 3) dementia (end stage disease) (Souslova, Tatiana et al).
One of the major challenges is to understand clearly the disease pathophysiology. There is still a lack of understanding but there is a dominance of amyloid hypothesis. But there are so many other challenges that include the anaylisis of in-vivo imaging in comparison with In-vitro diagnosis, the measurement of biomarker levels
One of the major challenges is to understand clearly the disease pathophysiology. There is still a lack of understanding but there is a dominance of amyloid hypothesis. But there are so many other challenges that include the anaylisis of in-vivo imaging in comparison with In-vitro diagnosis, the measurement of biomarker levels