Age Is An Important Factor On The Response Of Brain Tumors From Chemotherapy, Radiation, And Surgery

951 Words Oct 20th, 2014 4 Pages
Age is an important factor in determining the response of brain tumors to chemotherapy, radiation, and surgery. Patients over sixty years old have a lower response rate and shorter duration of response than younger patients. Tumor cells from younger patients were sensitive to BCNU, but cells from older patients barely responded to the BCNU. Only a few studies evaluate age as a parameter of response. Older patients may have to take medicine due to chronic illnesses, and this means that there should be special attention to those patients because the drugs could mess up the treatments. Also, older patients have a decreased creatinine clearance that must be considered when calculating the dose of the chemotherapeutic drug (Medscape).
Headaches are the most common symptom, but just because there is a headache does not mean that a brain tumor is present. Location of the brain tumors can vary the different placements of headaches. Some of the headache symptoms include a headache that appears in the morning after waking up and clears hours later, a headache that occurs during the nighttime and may cause vomiting, throbbing of the head, weakness or numbness or double vision, and a headache that can become worse by just coughing or exercising. Approximately half of the patients with brain tumors will experience a seizure within the time of having the tumor. It is the most common symptom in older patients. Some tumors are more likely to affect only one area of the brain and in that…

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