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14 Cards in this Set
- Front
- Back
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What is the action of interferon family |
Antiviral proteins |
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What is the action of chemokine family |
Direct cell migration adhension and activation |
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What is the action of TNF |
Regulate inflammatory and immune responses |
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What is the action of interleukin family |
Variety of actions dependent upon interleukin and cell type |
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What is the action of haematopoietins |
Promote cell proliferation and differentiation |
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What is the action of transforming growth factor beta family |
Regulation of immune cells |
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What length of Intracellular tail do cytokines receptors have |
Often have a short Intracellular tail |
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What do different cytokine receptors use difference combinations of |
JAK/STATS |
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What does JAK link the IL-6 receptors to |
ERK and PI3kinase pathways |
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What is the name of cytokine linked to cell death, inflammation, immunity and sepsis |
TNF |
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What is a target for auto immune diseases |
TNF |
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What is a good model for cytokine signal transduction |
TNF |
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What is the first use of antibodies as therapeutic agents |
TNF |
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What do antibodies generated in rabbits and mice make tools for |
Study in vitro and Vivo but also therapies |
