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28 Cards in this Set
- Front
- Back
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What alpha 1 agonist is used for nasal decongestant |
Phenylephrine |
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What alpha 1 agonists are used for prolong local anaesthetic action |
Adrenaline and phenylephrine |
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What alpha 1 are used for anaphylactic shock |
Adrenaline and phenylephrine |
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What alpha 2 agonists are used for antihypertensives |
Clonidine Methyldopa |
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What alpha 1 antagonists are used for hypertension resistant to other drug classes |
Tamsulosin Doxazosin Prazosin Labetalol Indoramin Terazosin |
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What is blood pressure |
Cardiac output x total peripheral resistance |
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What is cardiac output |
Heart rate x stroke volume |
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What is the homeostatic mechanism when there is a decrease in blood pressure |
Baroreceptor reflex Increase in sympathetic reflex Increase in HR and TPR Increase win blood pressure |
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What is BPH |
Benign prostatic hyperplasia |
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Where is the prostate |
Lies below the bladder and surrounds the urethra |
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How does the prostate enlarge |
Due to growth of strongly cells |
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How is urination made difficult by BPH |
Difficult due to obstruction |
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Why does BPH not cause cancer |
Benign |
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What drugs are used for BPH |
Tamsulosin, Doxazosin, Prazosin, labetalol, indoramin, terazosin |
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What do alpha 1 antagonists do to BPH |
Decrease in obstruction of urethra Decrease restriction of i time flow |
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Examples of beta 1 antagonist |
Atenolol, metoprolol, bisprolol, labetalol |
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What are examples of beta 2 antagonists |
Butoxamine |
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Examples of non ale river beta antagonists |
Pindolol Carvedilol Propranolol Sotalol Timolol |
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What effect do beta antagonists have on anti hypertension |
Decrease in cardiac output Beta 1 antagonist Beta 1 antagonism in heart Decrease HR & CO Reflex vasoconstriction results in increase in TPR |
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What effect do beta antagonists do to sympathetic nerve discharge |
Decrease in nerve discharge from cns Decrease baroreceptor sensitivity results in Decrease in baroreceptor reflex which results in Decrease stimulation of NTS |
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What happens when beta antagonists don’t have enough O2 |
B1 block in heart Decrease of HR and FOC resulting in Decrease in work Which leads to decrease in O2 demand |
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What happens to class 2 a todya rhythmic when beta agonists are used |
B1 block in the heart Regular newer beat restores |
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What is glaucoma |
Over production of aqueous humour |
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What is used to treat glaucoma |
B1 antagonist which decreases aqueous humour and intraoccular pressure |
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How are migraines treated |
Beta 1 blocker |
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What is used to treat anxiety |
Beta 1 blocker which decreases effects mediated by sympathetic nerves she decrease in heart rate |
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What are the side effects of beta blockers |
Fatigue and depression High conc of beta 1 antagonist may result in beta 2 blockage |
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What are examples of beta 3 adrenoceptors |
Amibegron Solabegron Mirabegron |
