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52 Cards in this Set
- Front
- Back
Titrimetric Analysis |
Is a traditional or classical method of quantitative chemical analysis based on determining the quantity of a reagent of known concentration that is required to react completely with the amount of active constituent is sample being analyzed |
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Titrant |
The solution being delivered from the buret |
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Titrand |
Substance being titrated |
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Titration |
Process in which a standard reagent is added to a solution of analyte until the reaction is judged to be complete |
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Indicator |
Often added to the analyte solution to produce an observable physical change |
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Beaker |
Used for mixing, stirring, and heating chemicals |
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Erlenmeyer flask |
Allows easy mixing and swirling of the flask without too much risk of spilling |
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Graduated cylinder |
To measure volume of liquids |
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Volumetric flask |
Used to measure an exact large volume of liquid |
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Cork |
stopper of volumetric flask |
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Pipette |
Measuring an exact small volume of liquid and placing it into another container |
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Burette |
A glass tube that is open at the top and comes to a narrow pointed opening at the bottom |
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Stopcock |
Right above the bottom opening of a burette is a _________ that can be turned to control the amount of liquid being released |
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Burette |
Used for extremely accurate addition of liquid, especially during titration |
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Aspirator |
A common source of contamination |
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True |
TRUE OR FALSE: Glass reagent bottles are not for alkalis or bases |
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Standard solution |
Solution of known concentration |
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Analyte |
Substance in a sample being analyzed |
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Equivalence point |
When the amount of added titrant is chemically equivalent to the amount of analyte in the sample |
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End point |
When a physical change occurs that is associated with the condition of equivalence |
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colorless |
Phenolphthalein color on acidic side |
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pink |
Phenolphthalein color on basic side |
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red |
methyl red color on acidic side |
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yellow |
methyl red color on basic side |
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yellow |
bromophenol blue color on acidic side |
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violet |
methyl violet color on basic side |
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yellow |
alizarin yellow color on acidic side |
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red |
alizarin yellow color on basic side |
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phenolphthalein |
The indicator used in the neutralization titration of acetic acid with sodium hydroxide |
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Direct titration |
Titrant is added to analyte until a reaction goes to completion |
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Residual or back titration |
Excess reagent is added to the analyte and the excess is determined |
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Blank titration |
It is to be conducted with the use of same quantities of the same reagents treated in the same manner as the solution or mixture containing the portion of the substance under assay, but with the substance itself omitted |
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Normality |
It is defined as the number of equivalents of solute per liter of solution |
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Primary standard |
Standard used for solids |
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Sodium carbonate |
What is the primary standard used in the standardization of 0.1N sulfuric acid |
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Content uniformity |
Assures that the strength of a therapeutic product remains within specified acceptance limit |
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Content uniformity test |
Used to establish within limits that a product has uniform amounts of AI in batch preparations of pharmaceutical dosage |
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95% - 105% |
USP specification for individual assay of NaHCO3 |
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85% - 115% |
USP specification for content uniformity of NaHCO3 |
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Quantitative transfer |
Transfer of a substance from one container or vessel to another without losing the content |
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Methyl red |
Assay of sodium carbonate tablets indicator |
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Faintly pink color |
Assay of sodium bicarbonate tablet end point |
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0.1N H2SO4 |
Assay of sodium bicarbonate tablet titrant |
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Methyl red |
Standardization of 0.1N H2SO4 indicator |
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sodium carbonate |
Titrand used for the standardization of 0.1N H2SO4 |
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0.1N H2SO4 |
Titrand used for the standardization of 0.1N NaOH |
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Milk of Magnesia |
Antacid suspension; white viscous liquid |
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Magnesium hydroxide |
Active constituent of Milk of Magnesia |
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0.1N NaOH |
titrant used in the assay of milk of magnesia |
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methyl red |
Indicator used in the assay of milk of magnesia |
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7-8.5% |
assay of milk of magnesia USP limit |
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Yellow |
Assay of milk of magnesia end point |