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187 Cards in this Set

  • Front
  • Back

What word describes a localized pocket of infection or purulent exudate surrounded by inflammation?

abcesses
What word describes a band of fibrous scar tissue forming an abnormal connection between two surfaces or structures (ie binding two loops of intestine together)?
adhesions
What word describes the abnormal destruction of tissues by activated digestive enzymes?
autodigestion (occurs in acute pancreatitis)
What word describes a round mass of food ready to be swallowed?
bolus
What word describes a stone developing in the body?
calculus
What word describes the obstructed flow of bile in the liver or biliary tract?
cholestasis
What word describes thick, semifluid mixture of partially digested food passing out of the stomach into the duodenum?
chyme
What word describes the surgical creation of an artificial opening from the colon onto the abdominal surface?
colostomy
What word describes the production of glucose from protein or fat?
gluconeogenesis
What word describes a hard mass of feces, often impacted, in the intestine?
fecalith
What word defines a polysaccharide, made up of glucose molecules, stored in skeletal muscle or liver?
glycogen
What word describes vomiting blood?
hematemesis (usually called "coffee ground vomitus because of the appearance)
What word describes a double layer of peritoneum that attaches to the back wall of the abdominal cavity and supports the small intestines?
mesentery
What word refers to the number of times a woman or female animal has given birth?
multiparity

What word describes abnormally high amounts of bile pigment (bilirubin) in the blood?

hyperbilirubinemia
What is another word for jaundice?
icterus
What word describes a surgical procedure that creates an opening from the ileum through the abdominal wall to function as an anus?
ileostomy
What word describes a blockage of the bowel with stool that results in severe constipation?
impaction
What is another word for chewing?
mastication
What word describes abnormally dark tarry feces containing blood?
melena (sign of an upper GI bleed)
What word describes small, hidden amounts of blood detectable in a stool test?
occult
What is another word for itching?
pruritus
What word describes the location behind the peritoneal membrane against the abdominal wall?
retroperitoneal
What word is a term used in anatomy that refers to a series of ridges produced by folding of the wall of an organ? (Most commonly the term is applied to the internal surface of the stomach)
rugae
What word defines a rumbling sound made by the movement of gas in the intestines heard from a distance?
borborygmus
What inflammatory lesion is associated with streptococcus sanguies and present as small painful lesions on movable mucosa, buccal mucosa, the floor of the mouth, the soft palate, or the lateral borders of the tongue?
aphthous ulcers
What term describes frequent bulky, greasy, loose stools that are foul in odor?
steatorrhea (characteristic of malabsorption syndromes - celiac disease or cystic fibrosis)
What is another word for stenosis?
stricture
What word describes a painful spasm of the anal sphincter along with an urgent desire to defecate without the significant production of feces?
tenesmus (associated with irritable bowel syndrome)
What is the condition called in which part of the stomach protrudes into the thoracic cavity?
Hiatal Hernia
What is the word that defines the formation of gallstones?
cholelithiasis
What is the word that describes the inflammation of the gallbladder and cystic duct?
cholecystitis
What is the word that describes the inflammation usually related to infection of bile ducts?
Cholangitis
What is the word that describes the obstruction of the biliary tract by gallstones?
Choledocholithiasis
What type of jaudice is the result of excessive destruction of red blood cells?
Prehepatic
What type of jaundice occurs with disease or damage to hepatocytes?
Intrahepatic
What type of jaundice is caused by the obstruction of bile flow into the gallbladder or duodenum?
Posthepatic
What stage of Cirrhosis in alcoholic liver disease is defined as enlargement of the liver and is often asymptomatic and reversible with reduced alcohol intake?
Initial stage / fatty liver
What stage of Cirrhosis in alcoholic liver disease is defined as inflammation with cell necrosis and fibrous tissue formation (an irreversible change)?
Second Stage / Alcoholic hepatitis
What stage of Cirrhosis in alcoholic liver disease is defined as fibrotic tissue replacing normal tissue with little normal function remaining?
Third Stage / end-stage cirrhosis
What enzyme is defective in celiac disease?
gliadin (breaks down gluten)
What word describes megacolon in children?
Hirschsprung disease
What word describes the twisting of the intestine?
Volvulus
Dehydration, acidosis, and malnutrition are complications associated with what two general conditions?
Anorexia and vomiting
What can be stimulated by distention, irritation, inflammation of the digestive track?
Nausea
What can be stimulated by smells, visual images, pain, and chemical toxins and/or drugs?
Nausea
Where is the vomiting center located?
medulla
What are the 6 steps of vomiting reflex?
Deep inspiration, closing glottis & raising the soft palate, ceasing respiration, relaxing the gastroesophageal sphincter, contracting the abdominal muscles, and reverse peristaltic waves
What is the presence of blood in the vomitus called?
Hematemesis (coffe ground)
What is the presence of yellow or green stained vomitus indicate?
Bile from the duodenum
What does a deep brown color volmitus indicate?
Content from lower intestine
What does recurrent vomiting of undigested food indicate?
Problem with gastric emptying or infection
What can prolonged diarrhea lead to?
Dehydration, electrolyte imbalance, acidosis, and malnutrition
What term describes watery stool resulting from increased secretions into the intestine from the plasma which is often related to infection and includes limited reabsorption due to reversal of normal carriers for sodium or glucose?
Large-volume diarrhea (secretory or osmotic)
What term describes stools that may contain blood, mucus, or pus while often accompanied by abdominal cramps and tenesmus and is often due to inflammatory bowel disease?
Small-volume diarrhea (tenesmus = painful spasm of the anal sphincter along with an urgent desire to defecate without the significant production of feces)
What term describes red blood that usually originates from lesions in the rectum or anal canal?
Frank blood
What are possible causes of gas?
Swallowed air, bacterial action on food, food or alterations in motility
What condition is associated with less frequent bowel movements than normal, small hard stools, can be acute or chronic, and sometimes associated with decreased peristalisis?
Constipation
What are common causes of constipation?
Weakness of smooth muscle due to age or illness, inadequate dietary fiber, inadequate fluid intake, failure to respond to defecation reflex, immobility, neurologic disorders, some antacids or iron medications, obstructions caused by tumors or strictures
Loss of hydrochloric acid from vomiting often results in?
Metabolic alkalosis
Severe vomiting leading to the loss of bicarbonate from the duodenal secretions often results in?
Metabolic acidosis
What type of visceral pain is associated with inflammation and ulceration in the upper digestive tract?
Burning sensation
What type of visceral pain is associated with stretching of the lliver capsule?
Dull, aching pain
What type of visceral pain is associated with inflammation, distention, and stretching of the intestines?
Cramping or diffuse pain
What type of visceral pain is associated with recurrent smooth muscle spasms or contractions that are a response to severe inflammation or obstruction?
Colicky (usually severe pain)
What term describes the type of pain that is identified over an area of inflammation when pressure is released?
Rebound tenderness
What type of pain is described as steady, intense, often well-localized abominal pain that includes involvement or inflammation of parietal peritoneum?
Somatic pain
What type of pain is perceived at a site different from the origin?
Referred pain
What type of pain results when visceral and somatic nerves converge at one spinal cord level?
Referred pain
What two diagnostic test may use radioactive tracers?
CT and MRI (can be used for liver and pancreatic abnormalities)
What is the congenital disorder that arise in the 6th or 7th week of gestation, results in feeding problem of the infant, impairs speech development, and is usually multifactorial in origin?
Cleft lip and cleft palate
What is the causative organism in thrush?
Candida albicans
What conditions predispose a person to developing thrush?
People on broad spectrum antibiotics, people undergoing cancer therapy, immunocompromised, diabetics
What is the causative microbe of Syphilis?
Treponema pallidum
What are the characteristics of the primary stage of Syphilis and how long does this stage last?
Characteristics include chancre (painless ulcer) on tongue, lip, or palate. This stage lasts 1 to 2 weeks
What are the characteristics of the secondary stage of syphilis?
Red macules or papules on palate (highly infectious)
What is the general treatment for syphilis?
Penicillin
What are the two causative microbes included in dental caries?
Streptococcus mutans and Lactobacillus
What chemical is mentioned as being responsible for dental caries?
Lactic acid
What is the "treatment" for caries?
Fluoride
Inadequate oral hygiene and toothbrush trauma which can lead to plaque build up are associated with what dental problem?
Gingivitis
Infection and damage to periodontal ligament and bone is associated with what dental disease?
Periodontal disease
What is the predisposing condition for periodontal disease?
Gingivitis
What is the pathology of periodontitis?
The organisms enter the gingival blood vessels and travel to the connective tissues and bone of the dental arch
What is the term that describes the thickening of the outer layer of skin?
Hyperkeratosis
What type of hyperkeratosis is described as a whitish plaque or epidermal thickening of the mucosa that occurs on buccal mucosa, palate, or the lower lip and can result in squamous cell carcinoma?
Leukoplakia
What is the common type of oral cancer?
Squamous cell carcinoma
What are the characteristics of a person that is likely to get squamous cell carcinoma? Where does it often occur?
Those who are smokers, have preexisting leukoplakia, or abuse alcohol often are at higher risk of getting squamous cell carcinoma. This often occurs at the floor of the mouth and lateral borders of the tongue
What patients are predisposed to acquiring Kaposi sarcoma?
aids patients
Lip cancer has a better or worse prognosis than most other cancers?
Better
What gland is most often affected in sialadenitis (inflammation of the salivary glands)?
Parotid
What virus infects the parotid glands and has a vaccine available?
Mumps
Noninfectious parotitis is usually caused by?
Lack of adequate fluid intake and mouth care in adults
What are the three main causes of dysphagia?
Difficulty swallowing is usually caused by neurologica deficit, muscular disorder, and mechanical obstruction
What type of cancer is esophageal cancer?
Primarily squamous cell carcinoma
What are the common associated chronic irrations with esophageal cancer and where does it usually occur?
Usually occurs at the distal end and is associated with chronic esophagitis, achalasia, hiatal hernia, alcohol abuse, and smoking
What is failure of the lower esophageal sphincter (LES) to relax due to lack of innervation called?
achalasia
What term describes part of the stomach protruding into the thoracic cavity?
Hiatal Hernia
What is the more common type of hiatal hernia in which part of the stomach and gastroesophageal junction slide up above the diaphram?
Sliding hernia
What is the type of hiatal hernia in which part of the fundus of the stomach moves up through an enlarged or weak hiatus in the diaphram and may become trapped?
Rolling or paraesophageal hernia
What are the signs associated with Hiatal Hernia?
heatburn, pyrosis, frequent belching, increased discomfort when laying down, substernal pain that may radiate to the shoulder and jaw
What term describes the periodic reflux of gastric contents into distal esophagus causing erosion and inflammation?
GERD or gastroesophageal disease
The severity of GERD, or gastroesophageal disease, depends of what?
Competence of the lower esophageal sphincter and delayed gastric emptying
Inflammation of the gastric mucosa with possible ulcers or bleed is characterized in which condition?
Acute gastritis
Atrophy of the stomach mucosa with possible loss of secretory glands, reduced production of intrinsic factor, and sometimes accompanied by H. pylori infection is characterized by which condition?
Chronic gastritis
What is the condition characterized by inflammation of stomach and intestine?
Gastroenteritis
What are the possible causes of gastroenteritis?
Usually infection but can include allergens to foods or drugs. Usually is self limiting
What is the etiology of Peptic Ulcer Disease?
H pylori
Where does PUD (peptic ulcer disease) normally occur?
Proximal duodenum and antrum of the stomach
What is the predominant factor in duodenal ulcers?
Increased acid secretions
In PUD, what are the causes of increased acid-pepsin secretions?
Increased gastrin secretion, increased vagal nerve stimulation, increased sensitivity to vagal stimuli, increased number of acid-pepsin sectretory cells in the stomach (genetics), increased stimulation of acid pepsin secretion by alcohol caffeine or certain foods, interference with normal feedback mechanisms, rapid gastric emptying
In PUD, what are some external causes of ulcers?
Ulcerogenic susbstances (NSAIDS, alcohol), glucocortcoids, and inadequate blood supply induced by stress, smoking, or shock.
What are the signs and symptoms of gastric and duodenal ulcers?
Epigastric burning or localized pain usually following stomach emptying
What are the treatments for gastric and duodenal ulcers?
Reduction of exacerbating factors, combination of antimicrobial and proton pump inhibitors to eliminate H pylori
What are complications associated with peptic ulcers?
Hemorrhage (first sign of PUD), perforation (results in peritonitis) , and obstruction(from scar tissue)
What kind of ulcer is usually associated with severe trauma (burns, head injury) or systemic problems (hemorrhage or sepsis)?
stress ulcers
What type of ulcer is usually rapid in onset with multiple ulcers forming within hours of precipitating event?
Stress ulcers
Where does gastric cancer usually occur and in what kind of tissue?
Usually occurs in the antrum or pyloric area. The tissue is usually the mucous glands
What are the causative agents of gastric cancer and what is the prognosis?
Diet is a key factor in gastric cancer, particularly smoked foods, nitrities, and nitrates. Genetics also plays a role.
What term describes loss of control of gastric emptying with the contents passed onto the duodenum without complete digestion?
Dumping syndrome
In dumping syndrome, hyperosmolar chyme draws fluid from vascular compartment into the intestine. What does this result in?
Intestinal distention, increased intestinal motility, decreased blood pressure, anxiety, and syncope.
Does hypo or hyper glycemia occur 2 to 3 hours after a meal in dumping syndrome?
Hypoglycemia
What is the treatment for dumping syndrome?
Frequent small meals that are high in protein and low in simple sugar carbs
What is the condition that primarily appears several weeks after birth that is characterized by projectile vomiting following feeding, firm mass felt in at the pylorus, and a lack of weight gain?
Pyloric stenosis
What do gallstones generally consist of?
Cholesterol, bile pigment, mixed content with calcium salts
What are the risk factors for gallstones?
Fat, female, high cholesterol in bile, high cholesterol intake, multiparity, any external estrogen or progesterone intake, hemolytic anemia, alcoholic cirrhosis, biliary tract infection
What are the signs and symptoms of large calculi obstruction of gallbladder duct?
Radiating pain, N&V, jaundice
What are 5 types of hepatitis?
Inflammation of the liver, alcoholic (fatty liver), idiopathic (fatty liver), viral hepatitis, infection elsewhere in the body (infectious mononucleosis or amebiasis), and chemical or drug toxicity
What word defines progressive destruction of the liver?
Cirrhosis
What are the common causes of cirrhosis?
Alcoholic liver disease, billary cirrhosis (immune disorder), postnecrotic cirrhosis (from chronic hep or long exposure to chemicals), metabolic (genetic)
In what ways does cirrhosis degenerate the liver function?
Extensive diffuse fibrosis interferes with blood supply, leads to possible bile backup, loss of lobular organization
What condition is associated with a decreased removal and conjugation of bilirubin, decreased production of bile, impaired digestion and absorption of nutrients, decreased production of blood-clotting factors, impaired glycogen metabolism, impared conversion of ammonia to urea, decreation inactivation of hormones and drugs, and decreased removal of toxic substances, reduction of bile entering the intestine, backup of bile in the liver (obstructive jaundice), blockage of blood flow through the liver (portal hypertension), and congestion of the spleen (increased hemolysis), inadequate storage of iron and b12, congestion in intestinal walls and stomach, development of esophageal varices, and development of ascites?
cirrhosis
What are ascites?
Accumulation of fluid in the peritonel cavity
What signs and symptoms are characteristic of initial cirrhosis?
Fatigue, anorexia, weight loss, anemia, diarrhea, dull aching pain in the upper right quadrant
What are the s&s of advanced cirrhosis?
Ascites and peripheral edema, increased bruising, esophageal varices, jaundice, encephalopathy
What are possible treatments for cirrhosis?
Avoidance of alcohol or specific cause, dietary restrictions, balancing electrolytes, paracentesis, antibiotics to reduce intestinal flora, liver transplant
What are two types of liver cancer?
Hepatocellular carcinoma and secondary (or metastatic) cancer (originates elsewhere)
What is the pathology of pancreatitis?

autodigestion of the tissue.



Proenzyme trypinogen activates to trypsin and activates other proenzymes into active foarms


Does the pancreas have a capsule?

No. Pancreatitis can lead to tissue destruction in local tissues beyond pancreas.

What are possible etiologies of acute pancreatitis?

Gallstones, alcohol abuse, intake of a large meal

What are the S&S of acute pancreatitis?

The primary symptoms are epigastric pain radiating to the back. Signs include shock, lowgrade fever, abdominal distention and decreased bowels sounds.

What is the treatment for acute pancreatitis?

Oral intake is stopped, treatment for shock and electrolyte imbalance if present, analgesics for pain

What is the name of the most common form of pancreatic cancer that arises from the epithelial cells in the ducts?

Adenocarcinoma

What is the prognosis for pancreatic cancer?

95% mortality rate

What is the name of the disease associated with malabsorption, is primarily a childhood disorder, seems to have a genetic link, and is a lack of a functional protein that breaks down gliadin?

Celiac disease (unable to process gluten-giladin is breakdown of gluten.)

What physiological effect does celiac disease have upon a person who ingests gluten?
A toxic effect on the intestinal villi that cause atrophy of the villi with subsequent malabsorption and malnutrition occurs
When does celiac disease generally occur?
4 to 6 months of age when cereals are added
What is the treatment for Celiac disease?
gluten free diet. Inestinal mucosa returns to normal after a few weeks without gluten
What are manifestations associated with Celiac disease?
Steatorrhea, muscle wasting, failure to gain weight, irritability, malaise
What are two types of chronic inflammatory bowel disease?
Crohns disease and ulcerative colitis
When does crohn's diesease usually occur? Ulcerative colitis?
Crohn's usually occurs during adolescence while ulcerative colitis occurs in the second or third decade.
Where in the digestive tract does crohns occur?
May occur in any area. Frequently occurs in small intestine
In crohns disease, affected areas of inflammation that are separated by areas of normal tissue are referred to as what?
"skip lesions"
What is a treatment for crohns disease?
Glucocorticoids
What is the pathophysiology of crohns disease?
Progressive inflammation and fibrosis often causing obstructed areas. Damaged walls impair processing and absorption of food. Inflammation stimulates intestinal motility. Adhesions between loops and fistulas may form.
Where does ulcerative colitis normally start? Where does it progress to?
Rectum then progresses through the colon
What are treatments for IBD?
Anti-inflammatory drugs, antimotility drugs, nutritional supplements, antimicrobials, surgical resection (colostomy or ileostomy)
There are 9 steps to appendicitis, what is the first?

Obstruction of the appendiceal lumen by a fecalith, gallstone, or foreign material

There are 9 steps to appendicitis, what is the second?

Fluid builds up inside the appendix which leads to microorganisms proliferating

There are 9 steps to appendicitis, what is the third?

Appendiceal wall becomes inflamed with purulent exudate formed. Appendix is swollen.

There are 9 steps to appendicitis, what is the fourth?

Ischemia and necrosis of the wall occurs which results in increased permeability

There are 9 steps to appendicitis, what is the fifth?

Bacteria and toxins escape into the surroundings

There are 9 steps to appendicitis, what is the sixth?

Abscess may develop which may lead to inflammation and pain temporarily subsiding

There are 9 steps to appendicitis, what is the seventh?

Localized infection or peritonitis develops around the appendix that can spread along the peritoneal membranes

There are 9 steps to appendicitis, what is the eighth?

Increased necrosis and gangrene occurs in the wall due to increasing pressure within the appendix

There are 9 steps to appendicitis, what is the nineth/

Appendix rupture r perforates releasing its contents into the peritoneal cavity leading to generalized peritonitis

What is the treatment for appendicitis?

Surgical removal of appendix and antimicrobial drugs

What are the S&S of appendicitis?

General periumbilical pain, N&V, LRQ pain with rebound tenderness at McBurneys point

What are the S&S of appendicitis after peritonitis develops?

Board-like abdomen, tachycardia, hypotension (from toxins in blood)

What is the word that describes an outpouching (herniation) of the mucosa through the muscular layer of the colon?

Diverticulum

Where do diverticulum form?

gaps between muscle layers

What are the treatments for diverticulitis?

Antimicrobials, dietary modifications to prevent stasis

What causes inflammation and infection in diverticular disease?

The stasis of material in the diverticula

What S&S are associated with stasis of material in the diverticula?

LLQ Cramping, tenderness, nausea, vomiting, slight fever, elevated WBC count

What age group does colorectal cancer normally occur in?

> 55

In colorectal cancer, what do most malignancies develop from?

Adenomatous polyps

What are risk factors for colorectal cancer?

Familial multiple polyposis, long term ulcerative colitis, genetic factors, environmental factors (ie low fiber, high fat and sugar diet)

What are the S&S for colorectal cancer?

Change in bowel habits (alternating diarrhea and constipation), bleeding, fatigue, weight loss, anemia

What is the treatment for colorectal cancer?

Surgical removal and/or chemotherapy, radiation

Where is the most common place for an intestinal obstruction?

Small intestine

What can cause an intestinal obstruction?

Mechanical obstructions (tumors, adhesions, hernias, tangible obstructions) and function/adynamic obstructions (impairment of peristalsis) that include spinal cord injury leading to lack of propultion of the instesint referred to pararlytic ileus.

What are possible causes of chemical peritonitis?
Enzymes released with pancreatitis, urine leaking from a ruptured bladder, chyme spilled from a perforated ulcer, bile escaping from the ruptured gallbladder, any foreign material in the cavity
What are possible causes of bacterial peritonitis?
Direct trauma to the intestine, ruptured appendix, intestinal obstruction and gangrene
What are the signs and symptoms of peritonitis?
Sudden and severe generalized abdominal pain, vomiting, abdominal distention, localized tenderness, dehydration, hypovolemia, low blood pressure, tachycardia, fever, leukocytosis
What are the treatments for peritonitis?
Massive antimicrobial drugs, possibly surgery
What are the possible treatments for intestinal obstruction?
Treatment of unnderlying cause, fluid and electrolyte replacement, surgery, antimicrobial therapy
What are S&S of large intestine obstruction?
Constipation, mild abdominal pain, abdominal distention, anorexia, vomiting, finally severe pain