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8 Cards in this Set

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  • Back
Class of acetaminophen
Analgesic, Antipyretic
Acetaminophen brands
APAP, Tylenol, Paracetamol
Acetaminophen MOA --> analgesic
inhibit synthesis of prostaglandins in CNS (via COX-1&2 inhibition) and peripherally blocks pain impulse generation
Acetaminophen MOA --> antipyretic
Direct inhibitory action of endogenous pyrogen on hypothalamic heat-regulating which increases heat dissipation via sweating and vasodilation
Acetaminophen Indications
analgesia, antipyretic
Acetaminophen dosing for children (>12) and MDD
10-15 mg/kg/dose q 4-6h prn
MDD 2600mg
Acetaminophen dosing for adults and MDD
325-600mg q 4-6h prn
650-1000mg q 4-6h prn
MDD 4000mg/day
Acetaminophen Warnings/Contraindications
Alcohol intake, hepatic dysfuntion, warfarin