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27 Cards in this Set

  • Front
  • Back
signs of spasticity, hypereflexia, and babinski signs are all signs of what involvement?
CNS disease
what is the most common brain tumor?
brain metastases
what are common signs of a brain Met or any tumor?
headache or cognitive impairment, if things evolve quickly Stroke, Hemmorrhage, seizure and or hydrocephalis
what is the most common cause of brain met?
lung cancer
what cancer has the highest popensity to cause brain met?
how does cancer spread to the brain?
hematogenous=blood flow
where are cancers commonly found in the brain in terms of gross location and arteries?
they are found where there is the most blood flow and also in b/t grey/white matter b/c that is where the arteriols are found
what are more common in brain tumors neurological signs or symptoms?
what is the most common type of headache involved in brain tumors?
tension type headache (bilateral) but accompanied with neurological signs
if the headache with a brain tumor is unilateral, where is the tumor?
why would a patient receive steriods as a first line treatment in brain mets?
they reduce the swelling in the brain and in lymphoma, the steriods may even break down the tumor
what are signs and symptoms of a spinal epidural metastases?
local and radicular pain in >95% of patients
what is the most common spinal region involved in spinal epidural mets?
where are most of the spinal mets coming from?
lung breast and prostate
what would you see in a spinal tap with a leptomeningeal mets?
elevated protein, pleocytosis, and lucky if you see the cancer cells
what is the most common source for leptomeningeal mets?
leukemia and lymphoma (or the non solid tumors) then after that are breast and lung
on neurologic examination, if you find there are multiple CN involvement which pass through the same formen, what tumer is most likely in this case?
leptomeningeal mets at the base of the skull
where would the tumor be if the brachial plexus is involved?
apex of the lung, compression on the plexus
what organs are commonly involved with lumbar plexus compression?
prostate, uterus, cervix, kidney
how are chemotherapy treatments neurotoxic?
they poinson the spindles, which is the transport system of the nerve for nutrients
what nerves will be effected with chemotherapy?
distal nerves because the microtubial spinals are not functioning properly to provide nutrients to the distal nerves
what does a PET scan measure?
activity and blood flow (metabolic activity) which is a way to differntiate between mets involvment or symptoms from radiation
what are signs and symptoms of radiation necrosis from chemotherapy?
behaves like a tumor with
increasing headache
increasing neurological deficits
mass effects
what differentiates between radiation necrosis and tumor?
PET which will allow to differntiate between metabolic activity
what is more common in brachial plexus radiation therapy?
pain and swelling
what region of the plexus is more commonly effected first in radiation therapy?
upper not the lower because the clavical protects the plexus
what is the most common neuropathy in chemotherapy?
peripheral involving distal and symmetric