Nervous System: Cancer Of The Nervous System

Front 1

signs of spasticity, hypereflexia, and babinski signs are all signs of what involvement?

Back 1

CNS disease

Front 2

what is the most common brain tumor?

Back 2

brain metastases

Front 3

what are common signs of a brain Met or any tumor?

Back 3

headache or cognitive impairment, if things evolve quickly Stroke, Hemmorrhage, seizure and or hydrocephalis

Front 4

what is the most common cause of brain met?

Back 4

lung cancer

Front 5

what cancer has the highest popensity to cause brain met?

Back 5

melanoma

Front 6

how does cancer spread to the brain?

Back 6

hematogenous=blood flow

Front 7

where are cancers commonly found in the brain in terms of gross location and arteries?

Back 7

they are found where there is the most blood flow and also in b/t grey/white matter b/c that is where the arteriols are found

Front 8

what are more common in brain tumors neurological signs or symptoms?

Back 8

signs

Front 9

what is the most common type of headache involved in brain tumors?

Back 9

tension type headache (bilateral) but accompanied with neurological signs

Front 10

if the headache with a brain tumor is unilateral, where is the tumor?

Back 10

ipsilateral

Front 11

why would a patient receive steriods as a first line treatment in brain mets?

Back 11

they reduce the swelling in the brain and in lymphoma, the steriods may even break down the tumor

Front 12

what are signs and symptoms of a spinal epidural metastases?

Back 12

local and radicular pain in >95% of patients

Front 13

what is the most common spinal region involved in spinal epidural mets?

Back 13

thorasic

Front 14

where are most of the spinal mets coming from?

Back 14

lung breast and prostate

Front 15

what would you see in a spinal tap with a leptomeningeal mets?

Back 15

elevated protein, pleocytosis, and lucky if you see the cancer cells

Front 16

what is the most common source for leptomeningeal mets?

Back 16

leukemia and lymphoma (or the non solid tumors) then after that are breast and lung

Front 17

on neurologic examination, if you find there are multiple CN involvement which pass through the same formen, what tumer is most likely in this case?

Back 17

leptomeningeal mets at the base of the skull

Front 18

where would the tumor be if the brachial plexus is involved?

Back 18

apex of the lung, compression on the plexus

Front 19

what organs are commonly involved with lumbar plexus compression?

Back 19

prostate, uterus, cervix, kidney

Front 20

how are chemotherapy treatments neurotoxic?

Back 20

they poinson the spindles, which is the transport system of the nerve for nutrients

Front 21

what nerves will be effected with chemotherapy?

Back 21

distal nerves because the microtubial spinals are not functioning properly to provide nutrients to the distal nerves

Front 22

what does a PET scan measure?

Back 22

activity and blood flow (metabolic activity) which is a way to differntiate between mets involvment or symptoms from radiation

Front 23

what are signs and symptoms of radiation necrosis from chemotherapy?

Back 23

behaves like a tumor with
increasing headache
increasing neurological deficits
mass effects

Front 24

what differentiates between radiation necrosis and tumor?

Back 24

fMRI
PET which will allow to differntiate between metabolic activity

Front 25

what is more common in brachial plexus radiation therapy?

Back 25

pain and swelling

Front 26

what region of the plexus is more commonly effected first in radiation therapy?

Back 26

upper not the lower because the clavical protects the plexus

Front 27

what is the most common neuropathy in chemotherapy?

Back 27

peripheral involving distal and symmetric