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35 Cards in this Set
- Front
- Back
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A dsynfunction in the hypothalamus is a (primary/secondary/tertiary) endocrine disease
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Tertiary endocrine disease
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A dsynfunction in the pituitary is a (primary/secondary/tertiary) endocrine disease
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Secondary endocrine disease
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A dsynfunction in the peripheral gland is a (primary/secondary/tertiary) endocrine disease
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Primary endocrine disease
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(primary/secondary/tertiary) are often the most severe because they often involve complete absence of the peripheral hormone
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Primary
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Hypothyroidism is a state where.....
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no enough thyroid hormone is produced
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Hypothyroidism causes an (increase/decrease) in metabolism
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Decrease
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Hypothyroidism cases metabolites called ...... which are compounds of sugar and proteins to build up
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glycosaminoglycans
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A build up of metabolites inside cells causes an (increase/decrease) in water and mucus
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increase forming oedema
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Growh hormone causes an (increase/decrease) in glucose uptake in muscle
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decrease
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Growh hormone causes an (increase/decrease) in lipolysis in adipose tissue
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increase
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Growh hormone causes an (increase/decrease) in gluconeogenesis in the liver
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increase
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Growth hormone's combined effect is ______/_________
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insulin resistance
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GH release is ....
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pulsatile
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Hypopituitarism is a deficiency of GH in children and results in
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pituitary dwarfism
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A GHRH analogue, ________ is used as a diagnostic test for GH secretion
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sermorelin
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An excess of growth hormones leads to _______________ in children
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pituitary gigantism
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An excess of growth hormones leads to _______________ in adults
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Acromegaly
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What is the peptide analogue of somatostatin used to treat disease where GH is in excess called?
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Octreotide
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What is the dopamine agonist used to treat disease where GH is in excess called?
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bromocriptive
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What is the inhibiting factor of prolactin release?
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dopamine
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The term for prolactin secreting pituitary tumour
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Prolactinomas
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If gonadorelin is given in pulses:
The results is a (stimulate for release or inhibit gonadotropin ) |
Stimulate for release
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If gonadorelin is given continously:
The results is a (stimulate for release or inhibit gonadotropin ) |
inhibit gonadotropin
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What is the name for synthetic GnRH?
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gonadorelin
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What are the 3 agonist used to treat endometriosis and in the short term use in the prevention of endogenous ovulation
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Buserelin
Luoprelin Naferlin |
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What are the 2 antagonists used in oncology to decrease the amount of testosterone in patient with advanced sympatomatic prostate cancer?
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Cetrorelix
Abarelix |
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_________ is a testosterone derivative that inhibits the relase of gonadotrophins used when decreased sex hormone would be beneficial
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Danazol
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What is the main disorder associated with ADH secretion?
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Diabetes inspidus
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What are the 2 main groups in which diabetes insipidus can be seperated into?
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Central
Nephrogenic |
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caused by loss of pituitary secretion of ADH and can be treated with ADH analogue such as demopressin
= (Central/Nephrogenic) Diabetes inspidus |
Central
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caused by impaired response to ADH at the renal collecting duct. Often acquired and treated by fluid replacement
= (Central/Nephrogenic) Diabetes inspidus |
Nephrogenic
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The term for the tetracycline antibiotic which appears to block ADH binding to its receptor.
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Demeclaycycline
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Carbetocin is an oxytocin used to?
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enhance labour and treat post-partum haemorrage
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Atrosiban & barusiban is used to?
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reduce myometrial contraction for pre-term labour
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In tumours oxytocins acts as a
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growth regulator through g-coupled transmembrane receptor
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