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19 Cards in this Set

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Gram negative infection

bacilli and anaerobes account for only 10-20% of infections in soft tisue and bone




most commonly seen in those that are immune compromised, have poor blood supply or have unusual exposures



Cellulitis

ecythma gangrenosum due to pseudomonas aeruginosa




hot tub folliculitis




with abscess following cat scratch accompanied with fever due to pasteurella multocida infectionB



Bite associated cellulitis

animal = streptococcus and staph, pasteurella multocida, capnocytophaga canimorsus




human = strep, staph, anaerobes, eikenella corrodens




treatmnet = irrigation, vaccination for tetanus and prophylactiv Antis

cellulitis case 2

after eating oysters in an alcoholic VIBRIO VULNIFICUS




exam presents with hemorhagic bullae on the extremities




may progress to shock in patients with liver disease




treat with 3rd generation cephalosporin or doxycycline

necrotizing fascitis

older woman with DM, has fever and progressive rash on inner right thigh and vulva




seen earlier with vulvar pruritis




treated with fluid resusication, antibiotics, extensive surgery and reconstruction




usually due to e. coli enterococcus, bacterocides

micro of NF

group A strept




Non group A strept




mixed gram negatives




anaerobes




MRSA

Dx

clinical; usually acute systemic toxicity painful or painless, erythema with swelling progresses to devitalization, and crepitus




management; appropiate antibiotics, srugery debridement and amputation ASAP

Necrotizing myositis

78 y.o. man presented with left elbow pain exam was unremarkable, several hours later severe pain, ecchymoses, blistering and crepitus of left elbow developed, he became hypotensive and unresponsive




antibiotics were begun, had quarter amputation and survived




blood cultures showed clostridium septicum




c. septicum

Myositis from direct inoculation

injection from steroids

Septic arthritis

swelling in joints after developing fever rash and having long term unprotected intercourse




neisseria gonorrhoeae, gram negative diplococci




dissemintaed GC can cause tenosynovitis, dermatitis, polyarthralgia or polyarthritis

dx and rx

culture of the synovial fluid has a sensitivity 20-50%




culture or nucleic acid amplification of mucosal speicmen is more sensitive




use antibiotics and joint drainage

Septic arthritis

50% staph




20-25% streptococcus




gram-negative 5% haemophilus 3% GC

Osteomyelitis

bone infection secondary to




hematogenous spread, long bones in kids, disc space to vertebral bodies in adults




contiguous focus with diabetes foot infection




penetating wounds

Osteomyelitis

staphy




gram negative bacili account for 10-20% via hematogenous spread




salmonella species in children with sickle cell disease




pseudomonas aeruginosa following puncture wounds of the foot




significant minority of contigous focus (often mixed anaerobes, staphy, strepto infections




mycobacteria

dx rx

blood and bone culture




treat with prolonged course og high dose antibiotics with surgical debridement if necessary

Lymphadenitits

regional= local infection with lymphangitic spread, GAS, enteric GNR, rare, Bartonella henselae - cat scratch fever, francisella tularensis tularemia, bacillus anthracis - anthrax nocardia species




generalized systemic infection viral infections or toxoplamosis

Cat scratch disease

bartonella




health 7 year old girl with swelling behind her left ear




no systemic illness




she had regular contact with cats and remembered being scratched 2 weeks earlier

Clinical cat scracth

lymphadenopathy, papule




heaptosplenic involvement




fever of unknown origin




dx with warthin starry silver stain




treat with macolides doxy and fluroquinolones

Zoonosis

dead rabbit




ulcer on thumb




francisella tularensis, tranmission via tick and deer bites in infected animales




clinical mainfestation as ulceroglandular , glandular, oculoglandular and orophaynfeal