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340 Cards in this Set

  • Front
  • Back
msk ankle

inversion sprain of ankle
- tests
- ligaments
INVERSION
lateral ligaments

Do anterior drawer
Talar tilt

#1 Ant talofibular lig
#2 calcaneofibular lig
msk ankle

eversion sprain
lots of swelling and pain after sig trauma - fell from big height
medial lig sprain
needs lots of trauma

deltoid lig

assoc Potts fx medial malleolus (tibia) or fx both malleoli

Medial muscle tendons T, D, Harry.
Tibialis posterior
flex dig longus
flex hall longus
post tibial art, vein, nerve
msk ankle

eversion of ankle and rotated while stumbled

pain, wont bear weight, but not as much swelling as expect for pain/disability
high ankle sprain

+squueze test
point tender over ant post ankle
spongy ankle

separation of tibia from fibular at sydosmoses and interosseus mmb

ant inf tibiofibular lig
msk ankle

ottowa ankle rules
wont walk/limp 4 steps
point tender distal 6 cm malleous ant/post

Do mid-foot also if:
wont walk
tender base 5th MTarsal or navicular (top of foot medial/middle)

Ottowa not for kids so much
Low specificity - false positives

Under 15% ankle inj have fx
msk ankle

+skin lesion

+ h/o trauma, intermittent swelling and grinding, possible fragment talar dome
skin ulcer -> osteomyselitits

Osetochondritis dessecans
msk arthritis

OA
RA
gout
septic joint
OA : pain with wt, better rest NSAIDS,

RA: multi joint, ulnar dev joints MCP

gout : swelling, 1st toe MCP

septic joint: RF IVDA/steroids
rot cuff muscles
msk shoulder
Who: over 40, poor vasc ; lots overhead use
Cause: fall onto shoulder/elbow
Present: pain lateral on deltoid, pain worse at night.
PE: + Neers and Hawkins
Impingement
Usually supraspin, can be infra

Rx: no xray, rest, ROM exercse
msk shoulder
Who: over 40, poor vasc ; lots overhead use
Cause: fall onto shoulder/elbow
Present: pain lateral on deltoid, pain worse at night.
PE: + Neers and Hawkins

Plus wasting infra and and supraspin muscles,
weak ext rotation

less pain passive vs active ROM
complete rot cuff tear

If want sx do MRI

rest.
msk shoulder

Pain ant, diffuse, worse after tennis/golf, baseball.

PE: pain with supination forearm, flex albow.
+ Speeds
biceps tendonitis.

If tear, usually proximal.

repair for comsmetic and for weak supination and flexion.
msk shoulder

Fell on point of shoudler/direct blow to post/lat shoulder.

+crossover test
Sprain/sep AC joint

Rx: ROM stength exercise
msk shoulder

M-aged pt with DM or thyroid dz
Ltime shoudler pain

pain over deltoid and resist ROM

hurts when sleep on that side.
poor passive and active ROM abduct, int and ext rotation/
adnesive capsultitis

PT
steroids IF EARLY
msk shoulder

fall on lateral shoulder
pain, swelling clavicle area
clavicle fx

if post-inf dispalcement can PTX or plexus injury

sling unless a kid
otc
oxymetazoline
topical decongestant

also naphazoline

3 days max
otc
- age for cold meds
- name antihist
- 4 for cold meds
- name antihist: diphenhydramine, chlorphenerimine
- expect: guarifensin
otc
spf meaning
types
SPF: 20 means stay 20x longer w/o burn.
SPF 15: 93% filtered.
SPF 30: 96.7%
dry shirt SPF 7
Water resist: 40' Waterproof: 80min
Do 30 min before sun. Reapply 2 hrs.
PHYSICAL barrier: zinc, titanium
CHEMICAL:

UVA: 320-340 longer wavelength, ages, skin changes, CANCER
mexoryl/ecamsule

UVB: 290-320, epidermis, burns
PABA/aminobenzoic, salicylates, cinnamtes

BOTH: avobenzone, benzopehenones, zinc

Should be 6M old.
otc

analgesics
max dose
APAP:
adult 4 g / 4000 mg day
children 10-15 mg/kg up to 5x day

ASA: adult 4 g/ 4000 mg

Ibu: adult 1200 mg, child 40 mg/kg
SE: ulcer, renal hep failure, HTN, periph edema.

keto: adult 75 mg
naproxen: adult 600 mg
otc
-plan b is what
- DEET
levonorgetrol
a progesterone
red chance preg 85-99%

no CI except est preg
---------------
DEET
10% last 2 hrs
23% lasts 5 hrs
up to 50% safe

KIDS:
recc 10% (last 2 hrs)
safe for over 2M to use 30%

lemon euc or picarin ~ 10% DEET
permetrin for clothes not people
msk knee

How: Injury when sudden decel when foot planted and twisted, pt then falls
Pres: Immediate fast effusion

+Lachman test: pt supine and knee at 15-30 degrees stablize femur and pull tibia forward
ACL tear

Immed fast effusion as artery here.
Pat often feels pop.
msk knee

How: car crash hit dashboard
Pres: knee may be hyperflexed.
PCL tear
msk knee

How: injury in day, wake up next day and swollen.
Pres: knee locks, also clicks of gives way in certain position.

PE: + McMurray > joint line tenderness
meniscus

pain mcmurray
foot full int rotation: lat men
foot full ext roto: med men

mcmurray pain w/o clunk = DJD

PE: also hemartrosis, dec ROM, quad wasting.
msk knee

valgus stress +
MCL

valgus knock kneed
bring foot lateral to knee
msk knee

varus stress
LCL

varus bow legged
bring foot in medial (knee sticks out)
msk knee

How: direct blow to lateral knee,
PE: Joint effusion ABOVE patella,
twisting injury where femur rotates medially with foot planted
patellar dislocation
uncommon.
usually lateral
msk knee

How: direct blow to anterior knee or avulsion to knee

PE: acute fast swelling in joint
patellar fracture
uncommon

for all patellar pathology: INHIBITION TEST
hold superior patella and have pt contract QUAD -> pain
msk knee

Overuse with jumping/kneeling.
quad tendon pain

STep stool test: one foot on floor, other on step of exam table. Lift foot off floor, place back down on heel, pain +
patellar tendinitis
patellofemoral dysfx
chondromalacia patella

ant compartment pain


w/ chondromalacia
PE: + McMurray > joint line tenderness
PLUS more pain with SQUAT
msk knee

joint effusion below patella
prepatellar bursitits
msk knee

wont bear weight or extend knee after a jump
fx tibial tuberosity
acne
whitehead vs black head
comedone, OPEN, blackhead
open follicle with plug, and dark debris
blackhead

comedone, closed,
papule with inflamm, REd
or w/o inflamm, WHITEHEAD

nodule, over 1.5cm
papule under 0.5 cm
acne
rf
RF

Meds: OCP, lithium, INH, pheny, halogen meds, steroids systemic
genes
oil, job at grill

NOT RF: stress, diet

+/- sun
acne

rx
1. assess adherence 1 month to OTC benz peroxide 5-10% (efficacy not dose reltd), improves desquam and antibacterial. open comedones/blackheads and whiteheads, contact derm in some.
2. salicylic acid: OTC 0.5% or 2%., whiteheads, pustular acne, inc cell turnover, NO antimicrob axn
3. top abx = systemic but cant get topical on back. Tetra bad for pregnant people but antimicro and antiinflamm.. Skin peeling.
4. top retinoids/tretinoin: peeling, good for closed comedones, whiteheads. stops new acne not treatment of current ones. Use at night, sun hypersens. TAkes 3 weeks.
5. retinaA: lab draws for lipids. Use if fail others and scarring nodulocystic.
acne
diff dx
rosacea
rosacea
flushing, telange, central face
no comedones

perioral dernatitis: papules, use top steroids on face
prev includes
immuniz
meds: HRT, ASA
screening : CA
education healthy behaviors
prev
woman age 22
TF ages 18-24
pap q3yrs
DPT q10 yrs
chlam test Q2 yrs
HTN Q2 yrs
prev
wmn age 30
TF ages 25-39

pap q3yr
DPT
HTN q2
prev
wmn age 45
TF ages 40-49

* MAMMO Q1-2 yrs starting age 40
pap Q3
DPT
HTN Q2
prev
wmn age 55
TF age 51-65

pap Q3
DP
T
flu vax starting 51
mammo (start age 40)
** colon cancer starts age 51
prev wmn age 68
TF age 66-70

* PNA vax once
flu yearly (age 51+)
DPT
mammo Q1-2 (start 40)
colon cancer starts 51
** osteoporosis screen age 60, DEXA 65
prev wmn age 74
TF
age 71+

flu
colon cancer until age 75
mammo Q1-2yr
osteo screen
prev men
25
TF men 21-34

HTN Q2yr
DPT
prev men age 40
TF men age 35-49
HTN Q2
DPT
** Chol Q5 yrs starting age 35
prev men 55
TF men 50-64
*colon cancer start 51
chol Q5 starts 35
DPT
* flu yearly starts 50
prev men
70
TF men 65 - death

colon cancer until age 75
flu vax
PNA vax starting age 65
DPT
** AAA if ever smoked
TF lifestyle type reccs
MVI folate women daily 30 yrs
3 smoke detectors, change batt yearly
bike helmet
dental Q6M, yearly xray
brush teeth and floss, change brush Q3M
TF
Insuff Evidence low risk

Dont screen asymto
Insuff ----------
dementia, DM , Drugs
fam viol, oral cancer , skin cancer
glaucoma, suicide, thyroid
prostate CA, lung CA

dont screen---------
Car art stenosis, PAD
scoliosis, testisular Ca,
EKG, stress echo
ovarian Ca, pancreactic CA
prev older
stroke
osteo fx
stroke
a fib use warf
control sys HTN

CV: ASA after 50, control HTN

osteo
exercise, bal and gait training, reduced use restraits, envir mods
DEXA after 65
height at every visit, loss of 2inches suggest osteo,
Recc Ca 1200 mg day and 400-600mg vit D daily
prev oldeuntil
older have
more automony
more use CAM, OTC
greater belief self eff
prev older
mammo
pap
breast exam
prostate
mammo: Q1-2 yrs until 75 then Q2-3 yrs, no upper limit if life expec over 4 yrs

pelvic: d/c over 65-70 if 3 paps nml, unless SA for STDs

breast: yrly

prostate: TF no DRE/PSA over age 75, often no recc Rx asympto men over age 75
prev

DM screen
Screen DM if HTN 135/80
prev older adult
ID
flu after 50
PNA after 65
tetanus
Zoviraz once at 60
prev older adult

ADLS
DEATH
dress eat ambulate
toilet hygience

get-up-and-go test:
get up from chair stright back, walk 10 feet, return and sit.
Nml 10 secs. ~ ADLS and fall risk.
prev older adult

IADL
SHAFT
shop, housekeeping, accounting,
food prep, transportation
prev older
drug coverage
1 stay medicare, decline drug coverage
2 stay enroll drug coverage plan
3 opt out medicare, enroll govt mgt plan with drug bene's

Meidcare does not dover H&P, eyes, teeth, feet, TETANUS
msk
deep hip buttock pain when walk, ok when sit

nml SLR, nml reflexes
spinal stenosis - claudication

under 25% +SLR or less reflexes
msk

38 wmn
tingle numb little finger, all of ring finger,

weak flexion of fingers and wrist

able to spread fingers fine
C8 : sensory loss pinkie and ring finger
and motor loss flex wrist and fingers.

Know C8 not Ulnar as interossei nml, and sens loss of ALL of ring finger not just partial.

carpal tunnel would have weak apposition of thenar/hypothenar

c6 is thumb and index finger.

c7 middle finger sensory, narrow band ventral forearm
msk mgt

1. MSK pain
2. worseing night pain, no trauma
1. NSAIDS, PT
2. MRI for cancer, esp if older breast cancer age
msk
whiplash
from hyperextension

1. films exclude fx
2. spurling test: specific not sens, painwhen turn head to side of injury
3. nml to have crepitus when push larynx back against vertebra, if gone, hematoma
msk
55 man
-less sensation radial side thumb and index finger
- nml triceps reflex
- diminished biceps reflex
- diminished elbow flex, and supination

What nerve/root ?
c6:


biceps is c5, brachioradialis is c6
tripceps is c7

If not better, next step B4 referrral to sx is MRI.
msk

55 yo man with DM
2 days severe back pain in thoracic spot
fever 100
WBC 16K
Stat MRI and neurosx conslt

epidural abscess
msk

45 yo healthy wmn
pain left hip below iliac crest 3 wks
radiates down ant thigh

can evert hip w/o pain
nml reflex, and SLr

tender distal iliac crest over prominence of hip bone
trochanteric bursititis
inject steroids or local
sports cv
describe murmur of hypertropic cardiomyopathy

Pulm stenosis
A sound of S2 louder vs Pulmonic

diamond shaped murmur

Louder with valsalva
Quieter with squat (pulm sten louder)


PS: loudest upper L sten, radiates neck and post lung fields

Need R heart cath b4 sports,
sports
to test steroids

female althlete triad
test-to-epitestosterone ratio

triad: amenn, eating d/o,osteoporosis
sports
concussion
grade 1
confused, amnesia less than 30 min,
No LOC
RX: can return to play if asym for 1 wk, stop if sx's again

grade 2
confusion with amnesia
LOC less than 5 min
amnesia less than 24 hrs
Rx: stop play, can return when asy for 1 wk

grade 3
LOC over 5 min
OR amnesia over 24 hrs
Rx: stop play 1 mnth, resume if asx 1 wk of play
msk carpal tunnel is what nerve ?

scaphoid bone aka
MEDIAN nerve

scaphoid bone aka carpal navicular, pa in snuffbox and when clench hands; immobilze 2 wks even if xray negative.
msk fight bite
cover gram negs (past and eik)
and gram pos

tetanus if needed
nsaids

look for 5th Metacaral
msk
ant dislocation hum head assoc w?
fx post lat humerus

if no fx, check radial and ulnar pulses and neuro,
then relocate
msk
review imaging for AC separation
?
msk tennis elbow
lat epicondyle - where brachioradialis goes
over use, worse with handgrips


can use glucocort
msk
20 yo female althlete
intermitt bil knee pain after volleyball, worse sitting w/ knees flexed to study

no effusion, no joint line tender,
yes lat subpatellar tenderness
patellofemoral instability
it tracks wrong and causes pain

OsgoodSch wld be pain on tibial tuberosity
msk

common finding with ACL tear
ACL tear:
+ ant drawer, swelling
+lachman

See also medial coll lig tear:
medial/lat joint line tenderness
* Valgus deformity with pressure applied
msk knee

* teen boy knee gets crushed by guy falling and knocking him over
* valgus test: 10 mm opening in flex and 8 mm in extension

no effusion, tender on joint line
neg lachmann
VALGUS:
bring foot out (knee in)

MCL tear or MCL/ACL tear
same boy but varus test positive
varus test: bring
(knee out) foot in
msk back

- walking shorter on one side
- antalgic gait
shorter on bad side
msk back

Pain c/w sciatica

and myofascial
Sciatica: radiates low back to butt to posterolateal leg
lumbsacral N compression

myofascial:
worst 1 hr after awaken/sit/stoop
worse with flexion/stoop - contracture
msk back
spondylo listhesis
listhesis : vert moves forward on one below it
msk back
how to do SLR per AHRQ
Hand on knee so fully extended.
Relax leg.
Hand cupped under heel, raise leg slowly.
+ Pain before hamstring strectched enough to move pelvis.

Ask where pain is.

then DORSIFLEX ANKLE -> if aggrevates or not the pain BELOW KNEE and then better when foot plantar flexion.

then try internal rotation of leg-> + worse c/w sciatic nerve.


Pain in other leg, more specific, less specific, radiculopathy. Looking for pain BELOW KNEE.
msk back What root/N

PAIN/numb: buttock down thigh and lateral leg
Motor: dorsiflex foot
R: Nml reflexes.
L5
PAIN: buttock down anterior thigh and lateral leg to side of foot.
NUMB: lateral shin
Motor: dorsiflex great toe, dorsiflex foot
Test : Cannot heel walk.
R: Nml reflexes.
LWW FM bk p 597
msk back what nerve/R

SENS PAIN: buttock, strip down back of thigh and calf (to lat foot)
NUMB: upper calf
MOTOR: plantar flex of foot.
Reflex: diminsh ankle jerk.
S1
LWW FM bk p 597
SENS PAIN: buttock, strip down back of thigh and calf (to lat foot)
NUMB: upper calf
MOTOR: weak plantar flex great toe and plantar flex of foot.
Reflex: diminsh ankle jerk.
msk back

S PAIN: low back, anterior thigh, front shin
MOTOR: extend quad
L4
LWW FM bk p 597
S PAIN: low back, anterior thigh, front shin
S NUMB: inside thigh at knee
MOTOR: extend quad
R: diminsh knee jerk
msk back
pain still there after one month
- no sign N root -> do EMG, if +, MRI
- signs N root -> MRI/CT is possible sx
- prior sx do MRI w/ con to tell hernia vs old scar
msk back
pt a truck driver
SX: back pain, worse when gets out of chair, limb with shorter leg/anaclitic gait
PE: SLR abn, pain hip flexion, trouble extending leg when sitting, pain on anterior thigh to palpation
Iliopsoas syndrome

Fix or get lordosis.
msk back

Hx: moving backs of mulch (stoop w. twisted torso)
Sx: pain mid buttock or low abd or groin or SI/trochanter

PE: pain to palp buttock by sacrum, and lateral by gluteal fold
Quadratus lumorum
Top myofascial pain syndrome
This m stablizes spine on pelvis and aids lateral bend.
msk back

unilat pain on SI joint
R/O Ank spondy
Schrober test: 2 marks (L5) should move apart with bend

Sacroiliac dysfx:
manip and sx help
msk back

activity reccs

return to work
+grad stretch and walk early
* 2-3 wks after onset low impact 10-20' daily then increase to 45' slowly

+ Most jobs RTwork 2-3 days w/o lifting
+ Phy active jobs in 1-2 weeks: caution rotate, rest, lifting.
+ sitting jobs: work up from 10-20' to 60' over 1-3 months
msk back
physical modalities
Manipulation : ok, stop if no help in 4 wks
PT : good
"slow sit back": push self up, roll spine down table. Helps flexors abs and hips. Do TID
msk back
Hx: fell onto butt
Sx: pain low back and down one leg to foot/tingle; painful to sit- lift one buttock up; walks with anaclitic gait
PE: pain with forced int rotation of leg at hip
PIRIFormis syndrome
Most sens test = rectal exam.

# Freiberg test is another diagnostic sign that elicits pain upon forced internal rotation of the extended thigh.
# The Beatty maneuver reproduces buttock pain by selectively contracting the piriformis muscle.4 The patient lies on the uninvolved side and abducts the involved thigh upward; this activates the ipsilateral piriformis muscle, which is a hip external rotator and, when the hip is flexed, an abductor.
# A painful point may be present at the lateral margin of the sacrum OR over trochaeric bursa/grt trochaner/lateral buttock

Exercise by cross foot over other leg, push down thigh.
msk back
this streches what ?
piriformis
msk back
this stretches what ?
q l
msk treatment myofascial pain
1. Aceto, NSAIDs
2. opiods no better than non-opiod
(no muscle relaxants- dont work)
3. maybe epidural injections/lido/Us trgigers, +/- evidence, try if to avoid sx
msk back
peds red flags
under age 4
kids asks to skip gym etc
over 4 wks
fever
postureal shift trunk/splints
limits motion
neuro change - rare root changes in kid
msk back
consult
acu: chronic
masage: myofacial
chiro: acute w/o radic in 1st month

sx: hernia disk and nerve roots if no improve 6 wks - 8 wks. Immed for bowel/bladder, prog neuro impair.

neuro: myelopathy, UMN, obscure cause

PMR: no change, no red flags

Anes: steroids
msk treatment myofascial pain
1. Aceto, NSAIDs
2. opiods no better than non-opiod
(no muscle relaxants- dont work)
3. maybe epidural injections/lido/Us trgigers, +/- evidence, try if to avoid sx
msk back
peds red flags
under age 4
kids asks to skip gym etc
over 4 wks
fever
postureal shift trunk/splints
limits motion
neuro change - rare root changes in kid
msk back
consult
acu: chronic
masage: myofacial
chiro: acute w/o radic in 1st month

sx: hernia disk and nerve roots if no improve 6 wks - 8 wks. Immed for bowel/bladder, prog neuro impair.

neuro: myelopathy, UMN, obscure cause

PMR: no change, no red flags

Anes: steroids
uri
adult
7 days been sick: had runny nose cough 3 days, better for day and half, then sick again.
thick rhinorrhea
decongestants not working
teeth hurt
sinusitis - suggest bacterial

double sickening
also poor transillum
facial pain w/ lean forward
cough at night
low smell sense
unilat facial pain
COPD
who gets O2
PaO2 under 55 mmHg
55-59 but with cor pulm, pulm HTN, or high RBCs
60 with sleep apnea or desat with exercise.

Suppl to paO2 of 60 or pulse ox 90%
COPD triage staging and when to refer
Spiro

FEV1 > 50% -> No ABG

FEV1 35-50% -> do ABG for eval of O2 need. Possible consult.

FEV1 under 35% -> ABG for O2 eval -> Pulm consult.

ALso consult for pulm rehab for:
over 2 hx or ED visits or sx that limit function.
COPD nutr
loss wt wtih nml serum albumin

suppl l carntine
COPD
OTC meds
abx
No cough meds
Only expect and mucolytics in acute exac.
chr bronchitis in acute can get Strep PNA, Hib, Morax catar, only use abx short term. no role for prophy.
COPD meds
intermittent
persistant
intermittent
SA inhaler br.dilator PRN: albuterol or ipratropium

persistant
SA or LA br, dilator inhaler DAILY
plus a SA PRN
OR
combo dilator+ICS
(ICS does not help long term disability or death but reduces exacerbations)

Inpatient for low O2 or high CO2

Can add theophylline
dm
5 features of metabolic syndrome
central obesity
DM2
HTN
low HDL
high Trigly

Others: PCOS, NASH, high uric acid, high PAF1, sleep apnea.
dm
gest dm
1. risk of DM2
2. screening
3. Rx
4. Goals
1. 50-70% chance DM2 later
2. screen 1hr GTT wk 24-28
3. Rx ins and metformin (catB)
4. Goals:
fasting under 90
2 hr post prandial under 120
DM
macrovasc comps
microvasc
MACRO
altheroscleorosis- CAD, PVD
Risk of CAD/stroke 2-4x

MICRO
retina, micro renal, neuropathy (hypotension, auto, tachy, gastrochesis)

T1 more retina
T2 more macro CVD, PVD
DM prevention
DM2
1: diet, exer, metformin
2: lower bg, ACE, weight control,
lipid contorl, control HTN
DM screening
TF:
None asymto
Screen HTN
High risk: obese, fam hx, gest,
other part of ins resistance syndrome

ADA
45+ Q3yrs
baby over 9 lbs , parent/sib DM
gest, sedentary
obese > 20% IBwt sp central
recur candida, prior glu tol probs
Parts ins resist: HTN, HDL < 35, tri > 250
Dm usual presentation
tired, weight loss due to hypergly

less common to see PU/PD polyphagia
DM
1. lab crit to diag
2. other labs drawn at diag
1. CRITERIA to DIAG
* one random over 200 plus sx'a
* 2 fasting over 126
* 2 2hr post prandial over 200
Any combo

DEF IGT: fasting 110-126, 2 hr 140-200

2. lipid, renal (K, creat, BUN), UA for ptn, A1c
Blood glu:
note fingerstick 7% higher than venous blood draw. (capillary blood more art vs venous)
If starting statin LFTs
Occ ECG is concern silent MI
occ c peptide if concern T1 vs 2.
DM goals for glu levels
...........ADA Endo Assoc
fast 130 110
pprand 180 140
A1c 7 6.5
DM
diet
exercise
ADA 1500-1800 cal start

to lose wt less 500 cal day than food history
fat 30% with 10% less sat fats
chol under 300
[ if chol/lipids an issue sat <7% chol < 200, if tri high then monounsat]
[ if nephro ptn at 10%]
Etoh lowers Bg
salt under 2000 if HTN
-------------
If microvasc - stress before exercise and prefer swimm, walk vs impact
DM which oral meds drop A1c the most
metfo, sulfonuea, repaglilnide 1.5-2%
thiazolidinedione 1%
acarbose 0.7-1%
DM oral meds effect weight and lipids ?
metformin(neutral or dec), incretin injectible : dec weight
sulfonureas (glip), insulin, thiazolid (pioglit), meglit (repag): gain weight
no change: sitegliptin , ?pramlitide, maybe metf
metformin and thizolidindiones: dec TG and inc HDL slightly
DM meds
which cause low glucose
aka cause ins secn ?
which dec ins resistance ?
Cause ins secn
sulfonureas so low BG.
repag/meglit - less low BG than sulfonurea
incretin but only if high BG

Do not cause low BG, no ins secn
metformin

Dec ins resistance
metformin, thiazin,

Acarbose: now low BG on own, can low BG with sulf/meglit. Does not cause ins release, delays absorb sugars.
DM meds
Monitors metformin ?
What monitors for piogliazone and rosiglitazonev ?
SE acrabose ?
Metformin: need good renal, liver, no CHF.
glitazones: LTFs before Rx and then moniter.
acrbose: gas, diarr as act on brush border
DM new meds
pramlitide
sitegliptin
incretin
8 pramlitide/amylin: slow gastric emptying, dec glucagon, dec A1c 0.5%
* sitegliptin/DPP-IV: slow GLP-1 breakdown, Doesnt delay gastric emptying, no wt loss, dec A1c 0.5-1%
* incretin: injectible SQ pre meals BID, glucagon like peptide : enhanced gluc relase only if glu high. SLow gastric emptying so feel full and loss weight.
DM
how to start insulin
Divide avg fasting glu by 18
Or
divide body wt in kg by 10

If to low, inc by 3 unit incements every 3-4 days.
Give half of needs long acting daily.
DM renal dz
Mainten
Goal BP under 130/80 or even 120/80
yearly urine dip alb and
serum creat if abn then ACE.

No EBM benefit to prophy use ACE.

Values on 24 hr collect OR spot
- nml < 30 mg/ 24 hr < 30 microg/mg
- microalb 30-300
- clin albuminurai over 300
DM retina
yearly exam
laser for PROLIF retinopathy

exudates, hemm, microanuer, neovasc
Dm lipid goals
total chol under 180
Trigl under 150
HDL over 45
LDL under 100 OR says ATP-III under 70

plus daily ASA
DM meds
fasting control
post prandial
FASTing
DM
metformin
Metformin = biguanide
USE: 1st line obese DM2
MOA: dec fasting, dec liver glu prod, de circ ins levels
Does not cause ins release, no hypogly.
SE: lactic acidosis, avoid CHF, liver renal fail, hypoxia, creat over 1.4
MoniteR: LFT, creat, cbc, b12
Other Effects: neut/wt loss, dec LDL and trigly
DM
thiazolidinedione
= pioglitazone rosiglitazone
MOA: inc ins-recptr, dec ins resistance, dec fastng glu, dec liver glu prod, inc muscle uptake, dec circ ins levels,
SE: weight GAIN
SE: liver probs, edema legs
Moniter: LFTs before start
DM sulfonureas
glipizide, chlorpropamide, tolbutamide, tolazamide, gynase, glimipride
MOA: ins secretalogues
Inc insul secn -> cause hypogly, dec fasting glu, may dec ins resist
SE: weight GAIN

USE: ok 1st line non-obses, add on with metformin
DM
repaglinide
a meglitinides
MOA: ins secretalogues, acts like sulfonurea, less hypogly; additive w/ sulfon and metfor,
USE: post prandial control, fast onset and lasts 2 hrs
DM meds
category of pioglitazone rosiglitazone
thiazolidinedione
DM med
name a meglitinides
= repaglinide
DM meds
acarbose
acarbose and meglitol both
a-glucosidase inhibotors
MOA: act brush border inhibit complex carb breakdown, delay absorb; delay not block absorb.
SE: gas, D, anemia
SE: as mono no hypogly but see w/ combo
DM maintenance surveillane
Yearly
microalb, dilate eyes, flu vax,

Q3M : A1c

Each visit: feet, BP ortho
DM how to start on insulin
Avg fasting glu mg/dl Divide by 18
OR
divide avg body wt by 10

Start long acting daily
HTN
when is syst vs dias bad ?
define iso syst HTN ?
Define pre HTN
Syst HTN bad after age 50.
Dias bad under 50
Isolat sys HTN : over 140/under90
PreHTN: 120-139/80-89
HTN
pt HTN
high LDL
not essential HTN
HTN as part of ins resistance
Other causes/things ask HPI:
estrogen meds, NSAIDS, triptans, decongest
HTN
PE signs co-arc
Nml between arms 10mm
CoArc between R brachio - L subclav: over 10 diff
CoArc above L subclav: weaker leg pulse vs arm

carotid bruits= ATHeroscle
HTN eye
Note: cant see vessel walls just blood column. So if art thicker wall, see narrow column.

Early: art narrow (thick wall), nicking, inc light reflex off art wall
LATE: hemm, copper wire(chol wall), silver wire (ca walls)
HTN due to pri aldo
high Na
low K
Same with Cushings: high glu,
HTN
diet
low Na, trial for 2 wks for response
INCREASE CA, K (positive ions/cations)
HTN
meds diuretics
HCTZ - thiazides, 1st line
SE: low K, worse BGlu
No good if creat >2

LOOP- lasix
USE: heart failure nad HTN

K sparing spiro
Use with HCTZ to lessen K loss, rarely used solo

DIUERTIC SE:
inc chol, inc Bglu, inc uric acid, tired, impotence
lipid
xanthelasma
xanthoma
xanthelasma
xanthoma on eyelid

xanthoma: yellow subdermal lipid full macrophges
lpid
prev lipid hyper
30-50% americans
Screen:
TF
men over 35, wmn 45
younger if RF CAD
ATP
Q5yrs after age 20
(fam hx high lipids, early cardiac death, stroke, claud, or mult RF CAD)
lipids
diet
3-7 day diet record
remove high fat, high chol foods
can lower by 5-15%
Goals - need counseling for this
under 200 mg day chol
ptn 15% cal
sol fiber 10-15g
total fat 30% cal,
mono up to 20%, warm-olive peanut
poly up to 10% temp corn canola
sat under 7% tropical - palm, coconut
lipid
most imp part interview
fam hx
lipid
what is measure what is calc
measure
total, TG, HDL
CALC
LDL: total=TG/5+LDL+HDL
VLDL=TG/5 as long as under 400
lipid how to get a pre-rx baseline
measure twice, at least week apart
fast 9-12 hours

unfasted: total up by 10 pts
TGs much higher
lipids
raise lipids
Raise LDL:
hypothy
nephrotic (also TG)


Raise TG
Chr renal fail
DM high TG low HDL
OCP, thiazides, pred
alcohol
pregnant

Drop HDL
etoh, sedentary
lipid
set pts target lipid
Determ RF, one point each
men over 45, wn 55, or posmeno
smoker
HTN
DM
CHD relative
HDL under 35

0-1 point: LDL under 160
2+ points under 130
2nd prevent/DM: under 100, or 70

Best TG under 150, high is +200
Best total under 200, high is 240
HDL under 40 is low
lipid
meds statin effects
Dec total chol, dec LDL, dec tri
AE: GI, h/a, myalgia,
Monitor LFT if pain CPK, fasting lipid
lipid
niacin
For increasing HDL
Effect: inc HDL, and good for all others
AE: bad glu, flush, ab pain, N/V. GOUT
Mon: LFT, uric acid, glu, fasting lipid
lipid
fibrates
gemfibrozil (gallstones)
clofibrate, fenofibrate

Use: High TG over 400
Effect: drops TG, inc HDL,
** some pts can inc LDL
CI: renal and hep probs
AE GI h.a derm,
* w. statins myalgia/rhabdo
Moniter: CPK, PT/PTT/INR, fasting lipids
lipid
bile acid seqiuest
cholestyramine colestpol
Por GI tol
Effect: drop LDL, inc HDL,
Rare inc TG
AE: GI, interfere absorb drugs, (dig)
lipid
diet for hdl d/o
diet TG d/o
use mono unsat fats
total fats 30% cal
TG: low FAT
lipid
pt on statin
has diffuse myalgia, no fever
stop meds (stain/ fibrate)
hydrate
serum CPK
UA for myoglobin/ptnuria
renal profile
If abn hydrate and fix lytes
Prav and fluvas less myalgia than others.
lipid
when check kids BP
what about kid with high lipids
age 3 check BP
child with high lpids: r/o 2ndry, refer, bile seq ok at age 10
Ped ranges:
total 200, ldl 130, hdl 35
tg 150
lipids
CAM
chromium inc HDL
fish oil help art, hyper TG
garlic lower LDL and TG
niacin lower TG and inc HDL
spy: lower LDL and TG
HTN urgency vs emergecy
HTN urgency
high stage II and sx's h/a SOB epistax, anx
HTN emer
>180/120, acute-> end organ damage
HTN in pts with ins syn vs NOT
pts ins resist if lost weight, exer may not need meds.
HTN
CCB
Less metabolic SE
may inc death in some pops: heart block, worsen heart failure,
h/a, constipation
periph edema
HTN
B blocker
brspasm, bradycardia
heart failure dec CO and exer tol
tired, depr
impotent

NOt great if young or exercising
HTN ACE ARBs renin Inhib
ACE
Great DM2 and good heart failure
AE: cough, HIGH K, angioedema
CI renal art stenosis, preg

ARBS no cough, HIGH K, angioedema

renin inhibitor: aliskiren, blocks making AngI
HTN
a blocker peripheral
a agonist central
labetolol
per a blocker terazosin
BPH
SE syncope, post hypo, tired

central alpha blockers
clonidine hydralzine methyl dopa
sedate, dry mouth, tired, imp
clon-rebound HTN

labetolol
combbo a and b blocker
hard to control HTN
HTN
AA
preg
AA: diur, CCB
Preg: methyl, beta, diur, hydralzine for emergency
NO ARB/ACE
pv
prev
prev: 25% couples, 11-22% womn primary care clinincs
phys role: abuse not norm, affects health, document injuries
screen for child abuse
pv
hx taking
avoid: abuse, violence
say: hit, hurt, threaten, are safe, how argue
AFRAID
assault, fear, rape, accused (things didnt do), isolation/intimidation, degraded (name calling, dismissed needs food clothing)
pv warning imminent danger
escaltion freq/severity
inc use etoh/drug either party
weopan in home
threat suicide either
abuse kids pets
pv preg
screen ea trimester
more common hep bor gest DM
vag
prev STI teens
Rx partner w/ STI
CDC 5 P's
1/4 teens get STI
W. + partner Rx women empiricly.
CDC 5 P's: partener, prevent preg, protection from STIs, practices, past hx STIs
vag
RF yeast
DM glu control
steroid use
use lower dose est in OCPs
HIV
vag
sx chemically vaginitis
d/c wh yellow
leukkorrhea
scant-> copius
>10wbc/hppf, no lactobacilli
inflmm
may or may not be maloder
vag
wet prep
low power wbc rbc hyphae
high lacto, clues, trich
vag atropic rx's
top need prog is have uterus
cream
ring for 90days
patch- les sfluc than oral
oral can cz N on empty stomach
vag
yeast inf preg
nystain tabs
mental
prev
Pri Prev
Sec Prev
-mental illness > HTN but under-recog
most fam exper Ment Ill
- anx and dep top 10 dx fam med
-Pri Prev: exer, less stress, strong self image> sleep, diet, no drugs, social support
- Sec Support: not validated, meds and therapy
mental
somatization
- one or mult visits
- avoid stone turning
- dont crit for not being stoic
- somat-mental AND mental to somatic (paralysis->depr)
mental
-cog therapy
-examine beliefs, shift irrational beliefs , to shift behavior
mental
-situational anx
- under 6M, reaction to acute event
- SI: just thoughts of death of suicide, OFTEN NOT intent/lplans
mental
Maj Depr
RF suicide
-diag: recur episodes last 2 weeks
50% recur after one episode.
- RF suicide (not just depr)
few supports, mult stressors, chronic medical conditions, substance abuse, senior age
mental
SAD
maj depr (2 weeks) related to season
can be late spring/summer & vegatating
OR
winter, atypical w/ sleep, irriatble, eating, rejection sensitivity
Rx: light rx>no rx; unsure whether meds or light better
mental
bipolar
BAD: depr and mania
dysthymia
cyclo: 2 yrs many hypomania episodes w/ depr mood periods
mental
GAD
OCD
PTSD
social
GAD: 6M worry concern Rx: buspirine an azapirine, non addicting
OCD: obses and comp, Rx: high dose SSRIs
PTSD:incl anhedonia, anger irritable avoidance startle detachment sleep issues
social/Soc Anx d/o: fear soc sit frightening/disabling
mental
depr history taking
abuse, meds, surgeries,somatic d/o
mental anx meds
ace-i, antidepr,
--
caffeine, decong
low glu w/ insulin

---ANX and DEPR
dronabinol, digoxin, steroids, stimulents
mental depr meds
Depr
alpha blockers, cancer meds, seizure meds, disopyramide, antihistamine, hydralazine, levodopa, metoclopromide, OCPs, procainimide

------
barbs, benzos, beta blockers,
medrozyprogest, narcs reserpine


---ANX and DEPR
dronabinol, digoxin, steroids, stimulents
mental
thyroid test ?
TSH hypothy -> silent hypo looks just like depr but depr goes away wiht treatment

thyroxine for hyperthy
mental
antidepr meds
wait 2-3wks b4 change dose.
2M for max effect. refer by 3M if not better.
proxac ahs one weekly drug
-TCAS: worse prostate hyper, constipation, hypotension, tacycardia, antichol, tremor, weight gain
- SRRI: same effect, less SE, long sex SE but others go away, N/D h/a agitation insom/sleepy
-MAOi: diet limits, drug-drug
mental
bipolar
mood stable first, if also depr can add anti-depr
- stable:
carb (check levels, check blood count for bone marrow supression)
gabapentin, lithium - check thy and renal and levels
olazapine: risk tard dysk
valproic acid: levels nad LFTs
aripiprazole: tard dysk
- 2nd line stable: topamx, tiagabine, lamotrigine
mental
kids
senior
preg
CAM
kids: need higher dose anti-psych, abuse can have same sx's as mental illness
Elderly: SA more successgul. Rx depr can help dementia. Use lower dose SSRI.
preg: SSRI ok, no stablizer when breastfeeding
CAM: st joh 300 mg TID
obese
weight classification
over wt bmi 25, 65% adults
obese 30
- class 1 30-35
- class 2 35-40
over 40 / class 3/ extreme obesity

extreme 15% Afr Amer women

Waist: over 40 men , over 35 womn
sinus
etiol

Define persist vs recurrnet
#1 viral
#2 bact: usually pos viral URI
- Strep PNA
- H inf
- Morax CAtarr (occ psudo, gr a strep, staph, anen, fungi)

Persist = after 21-28 days abx
Recurr: 3/more x year
sinus
rhinititis def
INFLAMMATiON not infecton
allergic
infectious
medicoamentosa
oocuap: chemical
vasomotor: no ientifiable allergen
sinus
films
for recurrnetl
*water view
ap view face nose raised 2-3 inches, chinon film ONLY for MAX sinusitis
*recurrent:
nasal cytology for eos, immunodef studies: ig types, hivtootal complemtn, complement
*films: CT=4 views films in cost
Signs film: mucosal thick, loss air space vol max sinus, opac or air fluid volumes
sinus anat adult vs kid
adults:
max, ethmoid
KIDS:
get max 1st (0-12M)
ethmoid * sinusitis
sphenoid * 4yrs old
sinus rx
amoxi 5-7 day. if not clear 14 days.
may take 8 wks treatment if chronic.
irragation, saline. decongeatants. steam

** NO anthistamine as these THICKEN mucus. Ok after resolves if have hay fever.
ha
aura ?
20--30% have aura
-fortification spectrum = jagged bright lines assoc w. visual migraine
- scotoma: black spot visual field assoc migaine aura
ha
cluster
not familial
ha temp arteritis
inc ESR
ha
dont imaging
prior identical ha
nml vitals
no acute neuro abn
supple neck
alert cog intact
imorovemtn w/o meds
ha daily, worse am, N, abd sx's, insomnia, resltelss, down, poor memory, hard concentrate
rebound, now taking med daily
ha
blur vision, sudden, N/V tearing worse wit stress
acute angle glaucome sarted antichol med
ha ci triptans, ergotamine, DHE
ischmic heart dz: angina, prior mi, silent ischemia, printzmetals
unont HTN, prior stroke, epilepsy, preg, raynauds, comp migraine (neuro deficit)
geri
IADLs
phone, travel, shop, make meal, housework, take meds, finances
geri ADL
physical ADLs
bath, dress, grrom, toileting, continence, transferring, walk, eat
SCale Indenpend, Assist, depend

Screenin functional problems simplfied:
hear, vision,
arm: touch back head and pick up spoon, fail -> OT
leg: get up and gom in under 20 sec and reach test (9-19 inches), fail -> PT
geri
MSE
Mood Asssessment
MSE
Folstein, MoCa(cube, clock, name, recall,attn, oreint)
time place orienation, regiatration, attn calc, recall , language, comrehension, read, write, visiospatial

Mood Assessment
Depression Scale
satified life, int activities/hobbie, qual life, boredom, spirit, fear, happy, outside activity, memory, desire live, worthiness, energy, life sit, view others
geri
warning signs live alone
any one
not eat right, personal hygiene, not dress for day, meds mistakes, housekeeping poor, falls or cant ambulate w/o aid, security concern/vulnerable, mental issues (fear, depr, agitat, calling 911/family alot), less independant wit finance/laundry/shop , lacks socialization
geri
PT
PT : Ms Phd
prevent loss mobility, reduce pain, restore function,.
gait, funct mobility, balance, posture, therpay exercise strengthen, neuromusc re train, wound care, leg injury, MSK injury, transfers
geri OT
BS or phd
ADL, adaptive equipment, cognition safety,
FINE MOTOR, splinting, arm function
visual perception, eval home
geri speech
dysphageia, augmentation, cognition, voice
geri all
behavior, inhibit casting (OT), family ed, recc d/c, strenthen and endurence
asthma
sx's 2x week, under 1x day
night time 3x month
FEV1 85% predicted
mild persistant
more than 2x month, under 1x day
night time under 2x week
FEV at least 80%

no peak flow
Use inhaled steroids say most- budesonide or cromolyn.
asthma
daily wheeze
night time 3x week
mod persist
asthma
dialy sx's
night time 4x week
use pred 3x year
severe persist
asthma Peak flow
gender, age, height
asthma
SE corticosteroids
thrush, dysphonia,
o\possible growth , bone demineral, early cataract
asthma
exercise
PRN albuterol
OR perexercise albut or cromolyn
\wors 5-10 min after stop
asthma
leukotrien meds:
mast cell:
leukotrien meds: montelukast
mast cell: cromolyn
eye
chalazon
* chalazon: focal lid swelling
mebomioin gland
compresses, topical abx
* diffuse lid swelling
cellilitis: IV ax and srugery
eye
orbital cellulitis
ptoposis
pain , dec vision, EOmvts abn,
bad pupil reflex as optic N swelling
eye
corneal abrasion
* trauma FB, -> topical abx, ppolytrim, daily f/u
* complicated/infection -> infilatrate, lens wearere refer
DEC VISION REFER
eye h/a
phtophobia deep eye pain
clicary flush: circum iris red
pupil assymetry
iriditis
pupil smaller on bad eye
pain in bad eye when shine light in other eye
svere eye pain
N/V, h/a, light halos, dilated pupil, hazy cornea,
acute angle glaucoma
high IOP
derm
non florinated/halogenated
hydrocort, elocon, westcort
Better for face, groin, baby.
SE: telang, candida atrophy, stria, delay healing, discolor, HPA supress, grow retard, HTN, ICP, glaucoma, cataracts
derm
ezcema
10% children. igE
perioral sparning, dennies (folds lowerlids), palmar markings
As age: FLEXOR creases.
Many outgrow with puberty.
Pri Prev: breast milk, no cow milk beef until 6M, no smoke, no day care until 2Yrs.
Sec Prev: bath, irritant avoidance
Rx ASA, moisture, cetaphil, avveno,
More severe: opt streroids.
2nd line: immunomodulators tacro/picrolimus, ok for face, intertirginous w/o risk atrophy if over age 2.
Do NOT use oral steroids.
derm aka neuroderm
lichen simplex chronicus
lichenified, skin colored.
SEVERE itching
back beck, top foot
linear
Rx steroid cream
derm
erosion:
ulcer:
fissure :
rash
erosion: to epidemis
ulcer: to dermis
fissure : to dermis
derm
Rx wet itching
benadryl, atarax,
domoboro/astringent: Alum sulfate and Ca acetate
derm
Rx dry itching
eucerin, aveeno, alpha-keri, less baths
derm
dyshydriosis rx?
topical steroids
papulovesicual, between finger, soles, palms.
Mild-sev itching.
RF: dermatitis-atopic, contact, ring worm
derm psoriasis
silver scales
Auspitz sign: pick and pinpoint red bleeding
EXTENSOR
(vs ecema FLEXOR)
Rx: steroids, tar, PUVA, mtx
derm
lichen planus
polygonal purple shiny, if place oil on it white lacy pattern.

Post TRAUMA, minimal scaling vs psoriais, linear at wrist. Occ oral or genitalia.
SEVERE ITCHING.
Poor Rx, try topical steroids.
derm
pityros
nonrx, wait 6-12 weeks.
derm
pemphigus vulgaris
Etiol: AI acantholysis to auto-ab
DecS: oral-> face, trunk, Symmetric.
Nikolsky: rub nml skin and then get blister.
EASILY BROKEN.
rx: pred and gold, can be fatal
derm
bullous pemphigoid
bulla on red base, FLexural or intertrigonous
Rx: oral steroids
derm
derm herpeti
symm groups vesicles scalp and butt,
wide spread
IgA
derm
blister after minimal trama
epidermolyis bullosa
derm
erythema multiforme
acute inflamm vascular
bug, drug, chem, systemic
TARGET, symm.
Can be mucus mmb
If severe steroids

NOT erythme chronicum migrans w/ lyme- central clearing and arthriris
derm eryth nodosum
shin, subQ fat inflamm
tender and red nodule
: TB , med, blasto, lupus
derm
palp purp petiche
mening, rocky tn, cancidan, strep, HSP
derm
brown to groin
erythasma
corynebacterium minutissimum
woods light coral red,
RF DM obese,
minimal itching
derm drug rxn rash
morbilliform
trunk out, symm, no palms/sole
supportive
derm ID
*measles: starts at hairline, drips down, koplick
* rubella: adenopathy
* rosella infantum: fever but look well, rash after fever
* ethy infectiousum: 5th, parvo, slapped cheek
*coxsakcie: hand foot mouth
derm bugs
chigger: redbug, harvest mite, bad itch at edge of clothes, burrows solution, antiitch

fleas: rxn to bite, burrows soln, anti itch

scabies: belt line, excorations, permetrin, lindane
derm kawasaki
Rx ASA mucocut LN syndrome, myocard, liver, renal, risk cor Art
derm tinea's
* t capitis: if kerion 4- wks griseo, keton
* t pedia: topical, #1 dermatophyte infection. 4wk rx
* t versicolor** pitysporum furfur, borwn, hypopig in summer, Selsun, antifungals
t cruris: ventilate clothes, powders, sharp border not on scrotum (VS candida: on scrotum, indefinate borders) Both +KOH, 2-3 wk rx,

Tinea capitus recurrance #1: siblings still has it. Check fomites !

Need oral meds: non local body, nails, hair, immunocomp.
Watch liver and interactions.

treat body and jock for 2 weeks after no sx's, topical ok.
Once start rx can go to school.
GRiseo: daily with fatty meal for 4-6 wks for 2 weeks after lesion gone.
Terbin: shorter course.
M canis: green under lamp, longer rx.

Kerions: antistaph abx, oral pred, f/u
derm
blasto
leprosy
B : warty growth, pustules
L: waxy, no sensation, dapsone
derm
vitiligo
cholasma
halo nevus
V: PUVA psoralen
C: depigment with hydroquinone
Lentigines: reina A, hydrquinone
halo nevus: gone on own
derm
discoid lupus
AI sharp demarc, center plaque /hyperkeratotic, atrophic, cheek.
Often with telangiectasia.
Not itchy usually.
hypo/per pigment.
VS systemic lupus, malar red and alopecia
derm
sclerodemra localized
sarcoid
dermatomyositis
slcro: white plaques, thick skin,
sarcoid: eryht nodosum, waxy face papules, eyelid, nares
d: gottens papules: knuckes, Rx oral c seorid
derm
papular circ or semi circ flesh colored
back o fhands or feet
ventral arms and legs
doesnt itch/minimal
granuloma annulare
derm
steroid potency
steorid type I>V
conc
vehicle (lotion < cream< gel< oint)
area applied to

Absorbtion more with: prolonged use, lg area skin damage, occlusion
Classify based on vascoconst assay.

Cream: pt prefer.
Lotion: hairy spot
Gel: stick but irriate inflamed area
Oint greasy, stick well and moisture for dry scaly lesion.
derm abx
1g cephalo : cephalexin
dicloxacillin
mucopiricin less severe
EZCEMA: bx r/o MRSA
derm
preg
- fungal
- scabies
- antihist
-fungal: all C, try topical
- scabies: sulfur
- loratidine, cetirizine
derm child scabies
NO lindane infant
under 2M sulfur ointment, 6% for 3 nights.
Over that permetrin
derm CAM
primrose oil, chamomile, witch hazel, jewelweed impatiens
derm contact derm
irritant mroe common than allergic
Patch: True Pos allergic dermatitis = itching, vesicle, rash lasting over 24 hrs, rash extends beyond site of application
derm
when oral rx poisen ivy
over 25% body
severe itching blistering
face hands genitals

60mg/day adults 1-2mg/kg kids
give at least 10 days
derm scabies
treat all house and sittes
DRYER
bag for 10-14 days
For naive it caan take 10-30 to gets sensitized to get itch VS days

RX
- child over 2M old lotion head to soles
- adol: neck down esp intertrig, nail, butt cleft, gentials. wash off in AM (8-14hr)

ALT: lindane 1%, MORE TOXIC - seizure esp young , old.
ALT ivermectin PO

Even if kill mite, ITCH FOR WEEKS., nodules for MONTHS.

F/u 2m for rx failure exam/r/o
5% permethrin
obese
bmi
weight kg
OVER
height meter SQUARED
under 1% have endo or 2ndry cause
obese
kids
*BMI over 85th at risk over weight
BMI over 95thile overweight
(early sign: cross 2 ile, rapid gain)
* 3/4 stay overwt as adult
*Focus wt maintenance.
*If stay overwt and comorbid,
loss of 2-4 lbs month.
1 hr exercise/day
obese waisr circum
WAIST: men over 40
women over 35
lower asian, AA, mexican
reltd CardioVAsc dz even if not obese

SKIN fold: anthropometric, tape and calipiers for muscular w/ BMI over 25
obese CA
colon, panc, GB
breast, uterus, cervix, prostate
obese exer
-sedentary adult 150 min/week
-FOr weight loss better is: 200-300/wk.
-best sustained 30min
-resist doesnt lose wt
- Posibly CV assessment if over 40, and younger if DM HTN unless already had on in office visit.

-kids: 1 hr day, under 2 hrs screen time day, None if under 2 yrs.
obese
wt loss goal
10% dec body wt over 6M at rate of 1/2 - 1 per week.

deficit 500 cal/day. One lbs=3500 cal
obese
CI
SE
CI severe med illness, severe obese, eat d/o need medical help
SE: cholecystitis if loss over 2 lb week or DM, maybe ursodeoxy acid.
obese
effect low calorie high fiber carb diet
if refined carbs
raise trigly lower hdl in some
obese
* effect low carb diet
* veggie
* high ptn lower insulin
less hunger,
may be easier to follow as elim lots foods.
* veggie: very ow fat, acceptable


Not recc if high fat, low fiber and nutr
obese
meal replacements
* replace: 1-2 meals frozen or liquid/creal/soup
obese
overall low calorie goal diet
low calorie diet 1200-1500 cal for 18 lb wt loss over 20 weeks
Over time, more reduction in cal for contd weight loss.

VERy LOW calorie: 600-800
- need app supressants and vit suppl/
- liquid sev weeks
loss 10-20 lbs over 12-16 wks
No better at one year.
obese beh mod
best learn in groups
higher retention, more wt loss.
obese
sx
- when refer
- outcome
refer: bmi 40 or 35 with comps after try 6M in wt loss program.
outcome: resolve DM, HTN apnea lpids.
Loss 25-44 kg/48-96 lbs , peaks at 2 yrs.
Preg ok but wait 12-18M.
obese sx types
Band/vertical band gastroplasty
just restirctive
- loss half excess body weight at 2 yrs.
- MM 0.1, 5%
Roux Y
malabsorb and restrict, better compliance as overeat causes bad sx's. Loss 60-70% excess wt.
MM 0.5 and 5%
Need suppl Ca B12 iron folate

RAre now bioliopanc diversion duod switch
obese suppl
Pot bad simmetics : PPE ephedra, bitter orange, country mallow, guarana, yerba mate.
No good: chromium, chitosan, guar, spirulena, butyrate, psyllim, yhimbe, st john, dandelio, theophylliine cream. DHEA, saacara

May be good and safe:
glucomannan, hydroxycitric acid, pyruvate, conj linoleic acid
obese meds
ALong with diet exercise
BMI over 30 OR 27 w. co morbid esp if plateu or rebound

rarely addmore than 5kg to diet/exer.
Rebound when stop med.

Orlistat: inhibit panc lipase. block absorp fat vits, so need vit.

sibutramine: NT reup inhib. Appetitie supressent. Cause inc BP and HR. CI if on SSRI or incont HTN or heart dz

older app supressents: phenteramine, diethylproprion : less data LT safety
Off mkt unsafe: fenflur, dexfenflur

Other wt loss meds: topiramate, zonisamide, fluvoxamine, high dose bupropion, metformin, exenatide
cam
herbs that interfere with clotting
ginkgo
garlic
ginseng


asa coumadin warfain
om
myringitis
omedia w/ effusion
my: red TM w/o effusion
OME: fluid in middle ear, no sx local or systemic illness
sub
discontinuation
wdrawl
wernickes
discontin: not due to toler or addiction but those can be present, avoid with taper

wdawl: sx's from subt that you are dependant on - phy or psych

Wernicke: THIAMIN
sub 5 As'
ANTICIPATE - all vulnerable, pri prevent, guide young
ASK and revisit
ASSSESS- those dependent foramt of use, comps,
ACCEPT- pts ds prob, dont say you hit kid when drunk(moralize)
ADVISE to stop, give reasons
ASSIST- in quitting
ARRANGE f/u, review relapses, (revisit assist)
APPLAUD all attempts at ea visti for 2 yrs.
sub CAGE
1. cut down
2. people Annoyed you by critisizing drinking
3. ever felt Guilty/bad about use
4. had drink first thing in AM to steady nerves or get rid of hangover
sub
Signs to assess for sub abuse
-parent complains sig beh probs in kid, assess kid and parent for subst abuse
-fam hx bipolar
sub TWEAK

(not in reading)
1. How many drinks does it take to make you feel high?

2. Have close friends or relatives worried or complained about your drinking in the past year?

3. Do you sometimes take a drink in the morning when you first get up?

4. Has a friend or family member ever told you about things you said or did while you were drinking that you could not remember?

5. Do you sometimes feel the need to cut down on your drinking?

The maximum score on the test is seven points, with the first two questions counting for two points each and the last three one point each. Note about question 1: If a woman responds that it takes three or more drinks to feel high, she scores two points. If she responds "less than three," she scores zero on the question.

A total score of two or more on the test is an indication of harmful drinking and further evaluation is indicated.
sub
labs abn w/ etoh
high ALT :ASP ratio 1.5
high PT PTT, low alb
high GGT
Panc: high amy lip
High trigly and uric acid
sub
smoking cess meds - MOA, CI
BUPROPION: antidep, CI eating d/o and seizures. SE: restless, insom, nausea,. Start 1 wk pre quit.
VARENICLINE: nic-R blocker. Caution h/o depr link suicide.
Nic replace: Use 8 weeks. gum SE nausea.
sub
alcohol meds
drug if liver fail
drug if renal fail
DISULFRAM: inhin Et dehydr. Useful those who relapse. Cause flush/N/V/h/a.CI: CAD, liver fail, pregnant, demented, HYPOTHYROID

NALOXONE: reduces relapse. CI pts on opiods, in acute withdrawl, hepatitis or liver failure.

ACAMPROSATE: maintain abstan. Reduces discomfort. CI: RENAL impairment, watch for depr.suicide

Drug liver fail: acamp
drug renal: naloxone, disulfram
otc
expire
2-3 yrs post manufacture
DOD: 90% good at 5 yrs except insulin, nitro, reconst antibiotics
otc
diarr
(text: 3 loose stools day)
kaopectate
pepto
Was attapulgite: water absorber, kids over 6, non-systemic, preg CI: bloody. mucus.
ACtion: dec # stools, harden

Bismuth subsalicylate: Pepto
antisecretory E Coli, anti-inflamm
CI: kids fever flu c pox Reyes, preg, renal failure, ASA allergy
otc
diarr
cause
warning sign
Causes: acarbose, SSRI, abx, dieur, PPI, thyroxine.
Warn: high fever, blood, over 3 days, eld, IC, severe abd pain
otc diarr
loperimide
polycarbophil
LOPER:
slow motility. Useful IBS
CI fever, bloody mucus, (on abx, h/o liver dz)

POLY: absorbs water like gel.
otc
consti def
medical:
"unsatif defecation fro infreq stool or diff stooling"
-12 weeks of 12M
ROME III
- strain or lumpy 1/4 stools
- sense incomplete evac or bloackage
- manual manuver
- under 3x week
Nml stool 3x day to 3x week.

ROME vs Doctor: ONLY 26% meeting Rome poop under 3x weeks.
VS patient: under 1x day, hard stool
otc consti causes
med:verap, narc, antichol, TCA, diur, antacid, clonidine, l dopa, laxtive abuse
Endo: hypothy, DM
Neuro MS Park paraplegia
CV sclero amyloid
preg, diet/exer low
obst
otc const w/u
*DRE
*colonscope: anor, wt loss 10#, anemia, new after age 50, blood stool
*warning: fever, N/V, IBs, cancer, old
* Lab thy, Abd, CBC, DRE guiac, scope
No red flags use OTC treatment, lifestyle, fiber (psyllium, beta glucan oat), laxatives.
otc consti
bulking lax
high fiber absorb water
SE bloat, fluid overload, impaction
psyllium metamucil
citracel methylcelluolse
benefiber guar gum
fiber sure inulin
polycarbophil
otc consti
osmotic lax
draw fluid in
mag salt: MOM, sodium phos (fleets enema), CI renal failure
lactulose, sorbitol, PEG
SE: bloat, gas, cramp
otc const
stim lax
alter mucosal perm, can addit and kill neurons
biscodoyl dulcolax
senna, casara/senokot
otc consti
supposotory
glycerin, biscodoyl
can irritate
otc consti
stool softener
Need lots fluids
DEc surface tension, inc bulk, allow fat and water to mix. binds bile salts.
Colace/docusate
mineal oil if not aspiration risk/demated and not pregnant.
biscodoyl is ?
stimulent
docusate is
stool softener
methylcellulose is
bulking
peg
osmotic
lactulose
osmotic
guar
inulin
bulking
senna casara
stimulent
otc
enema
and SE
phosphate, water, min oil, soap
SE trauma, HYPER PHOSPHATEMIA
herb
bad preg
hormonal: black cohosh, sawpalmetto
echinecea
kava
st john (also not for kids)
herb
bad heart
aconite, ephedra, licorice
avoid ginseng
low bp with black cohosh
herb
bad liver
** KAVA 25 cases severe liver toxicity
echinacea hepatitis
pennyroyal, comfrey, bush tea,
chapparral, germander, celandine, jin bu juan,
SENNA, skullcap-VALERIAN
Lipokinetics- has yohimbine
herb
bad neuro
aconite, ephedra (stroke, seizure)
pennyroyal (also bad liver)
ST john with SSRI-> Sero syndrome
VAlerian & kava additive with seds-hyp

h/a ginkgo and soy
herb
nephotox
aristochic acid = mu tong
aescin = horse chestnut seed
herb bad diabetes
ginseng and DM meds -> hypogly
herb bad bleeding
feverfew, garlic (anti-plt), ginger, ginkgo
ginseng + warfarin
herb
black cohosh
Useful hot flashes
Takes 5 weeks to work. dont use over 6M.
SE GI upset, hypotension.
CI preg-> miscarry.

Also soy, short term, modest effect for only 6 weeks. food safer than isoflavones.
SE: constip, bloat, N, allergy.

Not tested:chaste tree berry, dong quai, ginseng, even primrose oil, motherwort, red clover, licorice.
herb
saw palmetto
BPH: works ST, less good vs finasteride.
SE: ha, gi upset, diarr.
False + on PSA.
herb
garlic
Sterm bene lipid and anti=plt
SE: stomach upset.
Stop 7 days pre-surg as anti-plt -> bleed.
herb ginseng
Effects dementia, intermitt claudication.
Less good mem loss, tinnitus
SE: gi upset,h/a, allergy on skin
herb
st johns
depr use hypericin extract
SE: dry mouth, dizzy, consti, photosen
CI: preg, child, lactate
Interacts to cause sero synd: SSRI, MAO,
Interacts p450 up-reg: decreases DIGOXIN, AIDS prot inhib, OCPs, thephylline, WARFARIN
herb
ephedra
SE: HTN tachy, palps, MI, death.
Worse with symmimetics. Digoxin, guanethidine, MAO.
herb
echinacea
interacts immunusupre > dec action.
stop 3 wks pre-op
herb
OA
mild-mod OA
Takes 5 weeks to work.
glucosamine: **RAISE GLU IN DM, from FISH
chondroitin: from shark/cows, mad cow or metals

SE:GI upset, heartburn/N/
ALLERGY SHELL FISH
otc regs for meds otc
1938 fda drugs safe pre-marketing
1970 package insert
1972 FDA also OTC
1994 diet suppl health and educ act: suppl are food, no need to register, prove safety or efficacy.
prev
when screne for depr
adol 12-18
vax
vax age 4-6
dtap #5
polio #4
mmr #2
(varicella #2)
vax type hep b
3 dose (4 if combo)
fraction inactive IM
Who: ewnborn, adol, travel, liver dz, dialysis
born 2m 6m-2yr
CI: yeast allgy
100% effective
vax rota
2 dose 2m 4m
vax dtap
5 doses last at 4 yrs
Then age 11-12 booster TdaP if not had it yet.
2m, 4m, 6m, 15-18m, 5 yrs.
IM fractional inactv toxoid
risk pertu enceph
vax hib
Kids under 5
3-4 doses
2m, 4, (6m), 15m,
conj fractional polysacc
vax pneuma
Either SC/IM
Under 2 but over 6 wks: PCV
conjugate polysacc fractional
- all kids 4 doses: 2,4,6,12M
- at least one dose kids under 5

Over 2yrs sick, re-vax with
polysacc PPSV
vax flu
fract inactiv IM
Over 6M up to 18 yearly.
Nasal if over 2 under 50, not pregnant.
CI egg allgy
vax MMR
live subQ
Must be over 1 yr.
2 doses 1 yr 4 yr
LAsts 17 yrs, SE fever rash
OK HIV cd>200
vax hepA
whole inactiv IM
2 dose 1 yr 2 yr (3 in combo)
highest prev native Amer, lowest Asians
Who: liver dz, blood d/o, monkeys, travel, risky behav
vax meningitis
MENACTRA MCV4
fractional poly conj w/ diptheria, IM
Syllabus: 11yr-55yr
CDC: 2-55
All at 11-12, college dorms
2-11 no spleen etc.
CI: prior GBS

Menomune MPSV
subQ
under 2 (11), over 55
vax polio
whole inactive 4 doses
2,4,6-18m,4yr
vax hpv
fract inacti toxoid VLPs IM
3 dose $360
Who: 11-12, 13-18 catchup, less data 18-26
Myth: ok preg, no need pap or testing
95% effective,better natural inf
vax zoster
live atten subq
60-69 best efficacy
- dec 50% zoster, dec 40% neuralgia
- use before get zoster
- Risk giving c pox

CI: it is live - preg, tb, aids, pred,leul
ALL neomycin
vax tdap
IM fractional
tet, diptheria is toxin in formalin, 5 pertussis proteins
One time 19-64
age 11-12
If unvax: give Tdap, dt, dt
SE: arthus
vax IM vs subQ
IM: tetanus, hepB and A, flu, HPV, manactra

SC: MMR, varicella + zoster, menomune

Either: penumococcal
vax varicella
live atten subQ
2 dose: 1 yr, 4 yr
Who: born post 1986, health care, relative IC, teacher,
CI: preg, ALL neomycin, geltain, IC, TB
AE: 1% local pox, 4% mild general rash, zoster

87% effective
change
motiv interview tools
ready change ruler
agenda chart
Motiv Interviewing
- import confidence ruler
-decision balence score
Non Direct Interventions
probe priority to change
explore futures
-for ambiv
---double side reflect
----validate pts experience
----simple reflect
-for resistance
----emph pts responsibility and choice
----simple reflecton
change
stages of change
precontemp
contemp
prep
action
main and relapse
change
will act in 6m:
will act in 30 days -
acted in last 6M:
acted over 6M ago -
change
will act in 6m: contempalte
will act in 30 days - prep
acted in last 6M: action
acted over 6M ago - maintenance
change
denial, immune to harm, no control
unaware of harm
unwilling to try
PreContemplation
Do: give info of risks

Motivational interviewing- pre and comtemplation, understanding, empathy not admonish/confront.
- why change, what signs it is prob, have tried change b4.

No: rah rahs
change
"...but..."
may do something in next 6mnths
ambivalent
contemplation
motivational interview:why now, barriers, what keeps using, what helps change now, reason to not hcange now. what are needs to change now.
With resistance: empathy, thought provoking ?'s, "yes but..".
, health beliefs, CBT
open to info and education
Do: give ideas on facts for change,
Id supports for change
change
changing brands
beginning to set goals- quit date
action in next 30 days
Preparation
DO: praise, help set goals,
discuss plan for change.
Use CBT.
discuss coping and envir strategies and behav skills.
change
changed but under 6m
action
Do: CBT, reenforce committment.
encourage and praise.
ask about sucess and difficulties.
Id risks for relapse.
change for over 6m
main and relapse
encourage and praise.
(ask about sucess and difficulties.)
support, remove cues relapse.
If relaspse: motiv interview, what learned re self and process, Focus on sucess (they did quit x days), set new goals.
change
belief model
cult and spiritual relate to opinions on prevention and treatment and infl hleath related decisions. may be greatest influence.
Indiv act to prevent/change unhealthy behaviors IF they:
-perceive suspectibility
- perceive severity
(above both relate to threat of dz)
- peceived benefits if act
- per barriers lower than action