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54 Cards in this Set

  • Front
  • Back
What is the ALIMENTARY CANAL?
also known as the DIGESTIVE TRACT / GUT / Gastrointestinal Tract (GIT)
- it is the hollow tube from mouth
to anus
- considered to be external to the body
- relaxed is 9 meters long
- digests & absorbs food
Name 3 main ACCESSORY Organs
Pancreas
Gall Bladder
Liver
Name 3 sub-accessory organs
Teeth
Tongue
Salivary Glands
Name the 6 ORGANS OF THE ALIMENTARY CANAL
- mouth
- pharynx
- oesophagus
- stomach
- small intestine
- large intestine - this leads to the terminal opening (anus)
What is SALIVA's PROTECTION function?
- cleanses the mouth
- 1st line of chemical digestion (enzym Amylas breaks down starch)
- moistens food
- dissolving food to taste
What is INGESTION?
Taking food into the digestive tract via the mouth
What is MASTICATION?
chewing / mechanical digestion
What is DEGLUTITION?
Swallowing
What is PERISTALSIS?
(involuntary) Muscular contractions & relaxation that follows a direction
What is MECHANICAL digestion?
Physically prepares food for chemical digestion by enzymes. Mouth - chewing
What is a MECHANORECEPTOR
Stimulate smooth muscle of the GI tract walls to mix LUMEN (an opening) contents and move them along the tract, : Stomach - stretch sends message to brain saying "I am full"
What is a CHEMORECEPTOR
Located in the walls of the GI tract organs: Chemical messages, Ph in Stomach - eg: is more needed?, etc like digestive juices into the LUMEN or hormones into the blood
What is PROPULSION?
moves food through the ALIMENTARY canal, includes swallowing which is initiated voluntarily (peristalsis)
What is CHEMICAL digestion?
complex food molecules are broken down to their chemical building blocks by enzymes secreted into the LUMEN of the alimentary canal. Begins in the mouth and essentially complete in the small intestine.
What is ABSORPTION?
is the passage of digested end products (plus vitamins / minerals / water) from the LUMEN of the GI tract through the MUCOSA cells by active or passive transport into the blood or lymph.
THE SMALL INTESTINE IS THE MAJOR ABSORPTION SITE.
What is DEFECATION?
eliminates indigestible substances from the body via the anus in the form of feces.
TRUE or FALSE
Does the digestive system monitor itself independently of the nervous system?
TRUE
List the ORDER of digestion
- Ingestion (food into mouth)
- Mechanical digestion (chewing <segmentation>)
- Propulsion (swallowing <oropharynx> & Peristalsis <esophagus, stomach, small intestine, large intestine>
- Chemical digestion (stomach)
- Absorption (small intestine - lymph & blood vessels)
- Large intestine
- Defecation (terminal opening <anus>)
What is the GUT's BRAIN?
nerve plexuses, entire length of gut
What is SHORT REFLEXES?
STIMULI ARISES FROM WITHIN THE GIT
What is LONG REFLEXES?
- Intrinsic & extrinsic stimuli
- Involves CNS (autonomic)
Identify the LOCATION of the SALIVARY GLANDS
- parotid gland
- sublingual gland
- submandibular gland
How is salivation controlled?
primarily by the parasympathetic division of the ANS. when we ingest food chemoreceptors & mechanoreceptors in the mouth send signals to the salivatory nuclei in the brain stem
What are CHEMORECEPTORS most strongly activated by?
Acidic substances like vinegar / citrus juices
What are MECHANORECEPTORS most strongly activated by?
virtually any mechanical stimulus in the mouth
If the stomach is full of acid - why does it not EAT itself?
At the top of the gastric pit, we have mucous
What is the stomach PH?
Ph 1-2 VERY ACIDIC
Name the 3 stomach muscles
- Longitudinal layer
- Circular layer
- Oblique layer
Describe the GROSS STRUCTURE of the stomach
Top of the stomach is close to the heart, the cardiac sphincter stops the food from going back up, it can be held in the stomach by the pyloric sphincter.
Name the 5 SECRETIONS of the stomach
- hydrochloric acid (HCI)
- Pepsinogen
- Lingual Lipase
- Intrinsic Factor
- Enteroendocrine cells
State the FUNCTION of HYDROCHLORIC ACID
- secreted by Parietal cells
- extremely acidic
- denatures dietary proteins
- kills bacteria
State the FUNCTION of PEPSINOGEN
- secreted by chief cells which is the inactive form of Pepsin
- most important protein digesting enzyme
- once Pepsin is present, it also catalyses the conversion of Pepsinogen to Pepsin
State the FUNCTION of LINGUAL LIPASE
- released by the intrinsic salivary glands
- may digest some triglycerides (type of fat found in your blood) in the stomach
State the FUNCTION of INTRINSIC FACTOR
- secreted by Parietal cells (stomach epithelium cells)
- is required for intestinal absorption of vit B12
- needed to produce erythrocytes (red blood cells)
State the FUNCTION of ENTEROENDOCRINE CELLS
- release a variety of chemical messenges into the interstitial fluid
- histamine & serotonin & gastrin (a hormone that plays essential roles in regulating stomach secretion & motility {move spontaneously & consume energy})
Describe the 3 phases of GASTRIC SECRETION
- CEPHALIC PHASE : NO FOOD IN SYSTEM; using brain not stomach
(sight & thought of food, stimulation of sight & smell receptors)
- GASTRIC PHASE : FOOD IN STOMACH; getting ready to receive food, stomach starts stretching (stomach distension activates stretch receptors, food chemicals {especially peptides & caffeine} & rising pH activate chemoreceptors
- INTESTINAL PHASE : STARTING TO PUT FOOD INTO INTESTINE; arrive 1st part of small intestine, (presence of low pH, partially digested foods, fats or hypertonic solution in DUODENUM when stomach begins to empty
List the CELLS of the STOMACH
- Mucosus neck Cells
- Parietal Cells
- Chief Cells
- Enteroendocrine Cells
What do the Mucosus Cells of the STOMACH secrete?
- Mucosus Neck Cell
produce a thin, soluble mucus
What do the Parietal Cells of the STOMACH secrete?
- Parietal Cells
secrete HCl which makes the stomach contents extremely acidic, necessary for activation & optimal activity of PEPSIN, it also helps food digestion by denaturing proteins and is harsh enough to kill bacteria. It also secretes Intrinsic factor, which is a glyco protein required for vitamin B12 absorption in the small intestine.
What do the Chief Cells of the STOMACH secrete?
- Chief Cells
produce PEPSINOGEN, the inactive form of the protein-digesting enzyme PEPSIN.
What do the Enteroendocrine Cells of the STOMACH secrete?
- Enteroendocrine Cells
release a variety of chemical messengers directly into the interstitial fluid. Examples, HISTAMINE, SOMATOSTATIN, GASTRIN
What is the CEPHALIC Phase?
sight & thought of food, stimulation of taste & smell receptors
What is the GASTRIC Phase?
stomach distension activates stretch receptors, food chemicals & rising pH activate chemoreceptors
What is the INTESTINAL Phase?
presence of low pH, partially digested foods, fats or hypertonic solution in duodenum when stomach begins to empty.
Explain how gastric activities (gastric, motility & emptying) are regulated.
Stomach contractions not only accommodate its filling and cause emptying, but they also compress, knead & continually mix the food with gastric juice to produce chime.
Is SEROTONIN more prevalent in the brain or stomach?
stomach
When does RECEPTIVE RELAXATION occur?
in both anticipation of and in response to food movement through the oesophagus and into the stomach; the process is coordinated by the swallowing centre of the brain stem & mediated by the VAGUS nerves acting on serotonin.
What is GASTRIC ACCOMMODATION an example of?
it is an example of smooth muscle plasticity; to be stretched without greatly increasing its tension.
What does GASTRIC CONTRACTILE ACTIVITY exhibit?
in the oesophagus, the stomach exhibits PERISTALSIS. Normally each "wave" squirts 3ml or less of CHYME into the small intestine.
Describe the REGULATION of GASTRIC EMPTYING
- the stomach usually empties completely within FOUR hours after a meal;
- fluids pass quickly through; solids linger, remaining until they are well mixed with gastric juice & converted to a liquid state;
- gastric emptying depends mostly on the contents of the DUODENUM;
- the stomach & duodenum act in tandem; as chyme enters the DUODENUM, receptors in its wall respond to chemical signals & to stretch, initiating the enterogastric reflex & hormonal mechanisms that inhibit acid & pepsin secretion.
- when chyme entering the DUODENUM is fatty, food may remain in the stomach 6 hours or more.
The enzymatic breakdown of any type of food molecule in water is called
hydrolysis
The terminal portion of the small intestine is known as the
ileum
You have just eaten a meal high in complex carbohydrates. Which of the following enzymes will help to digest the meal?
a. amylase
b. cholecystokinin
c. gastrin
d. trypsin
a. amylase
which BRANCH of the ANS is most important to GASTRIC ACTIVITY?
Parasympathetic